SuperArray Bioscience Releases Over 36 Pathway-Focused Real-Time PCR Gene Panels For All Stages Of Drug Discovery And Development

Main Category: Genetics
Also Included In: Biology / Biochemistry
Article Date: 03 Aug 2006 - 0:00 PDT


SuperArray Bioscience (http://www.SuperArray.com) announced today that it will feature its real-time RT2Profiler(TM) PCR Arrays at the upcoming Drug Discovery Technology meeting at the Boston World Trade Center and Seaport Hotel from August 8 to 10. The RT2Profiler(TM) PCR Arrays now encompass over 36 different human and mouse pathways or disease states. In these PCR Arrays, SuperArray has combined its expertise in SYBR Green real-time PCR with its leadership in pathway-focused gene expression arrays. The resulting technology is designed for a wide variety of applications including drug discovery.

"Focused gene expression analysis by real-time PCR is increasingly used during the pharmaceutical screening process," said David Martz, Director of Sales and Marketing at SuperArray Bioscience. "From target identification and evaluation, to optimization and development, the expression pattern for specific subsets of genes needs to be characterized and monitored. Our cataloged PCR Arrays focus on disease states and biological pathways important for general candidate screening purposes, like cancer and diabetes, or apoptosis and toxicology. We also produce custom PCR Array plates with gene lists for individual discovery and development projects," continued Martz.

The RT2Profiler(TM) PCR Array is a 96-well plate containing primers for a thoroughly researched panel of relevant, pathway or disease-focused genes plus appropriate positive and negative controls. For a guaranteed assay system, SuperArray strongly recommends taking advantage of their SYBR Green expertise and combining the PCR Arrays with one of their optimized and instrument- specific real-time PCR master mixes.

"With our PCR Arrays and master mixes, researchers are using their real- time PCR instrument just like a microarray. In fact, we will also be presenting a poster at the meeting showing how our toxicology PCR Array provides confirmatory real-time PCR results for the observed liver toxicity of glitazone PPAR-gamma agonist drugs for type 2 diabetes," added Martz.

More information about real-time PCR Arrays may be found on the company's web site at http://www.superarray.com/PCRArrayPlate.php, including a complete list of available pathways, custom design options, and the associated PCR master mixes.

SuperArray Bioscience Corp.
http://www.superarray.com

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