National Ovarian Cancer Coalition Joins The Gynecologic Cancer Foundation In Announcing First National Consensus On Ovarian Cancer Symptoms
Main Category: Ovarian CancerAlso Included In: Women's Health / Gynecology; Public Health
Article Date: 14 Jun 2007 - 0:00 PDT
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The National Ovarian Cancer Coalition (NOCC) today joins the Gynecologic Cancer Foundation and other national organizations in announcing the first national agreement on ovarian cancer symptoms. Often referred to as the "silent killer" due to the common belief that there are no warning signs or symptoms, ovarian cancer is the most deadly reproductive cancer.
The Gynecologic Cancer Foundation led this effort to form a consensus in response to ovarian cancer survivors who long held the belief that there were common symptoms of ovarian cancer. Researchers, including Dr. Barbara Goff, a gynecologic oncologist at the University of Washington, have conducted conclusive research that demonstrates that the following symptoms are much more likely to occur in women with ovarian cancer than women in the general population. These symptoms include:
-- Bloating
-- Pelvic or abdominal pain
-- Difficulty eating or feeling full quickly
-- Urinary symptoms (urgency or frequency)
Women who have these symptoms almost daily for more than a few weeks should see their doctor, preferably a gynecologist.
"This agreement on common symptoms of ovarian cancer hopefully will lead to earlier diagnosis when a cure is more likely," said Dr. Goff. "We know that when women are diagnosed in Stage I of the disease, it is 90% curable. Unfortunately, until now there has been no agreement on common symptoms, allowing women to go undiagnosed, despite visits to the doctor, until it was too late."
"Because there is no screening tool, it is crucial that the medical community has come to a formal consensus that symptoms of ovarian cancer exist and the appropriate action needs to be taken immediately when women discuss them with physicians," says Jane Langridge, chief executive officer of NOCC. "Ovarian cancer is taking far too many lives and we hope these findings jumpstart public dialogue and awareness to ultimately improve survival rates."
It is estimated that more than 22,000 women will be told they have ovarian cancer this year and more than 15,000 will die from this deadly cancer. Ovarian cancer ranks fifth in cancer deaths among women. At present, about 80% of these cancers are not diagnosed in their early stages, leading to a reduced chance of survival.
"In response to the lack of awareness of ovarian cancer symptoms, NOCC recently launched the 'Break the Silence' campaign to educate women about the signs and symptoms of the disease, and to encourage them to pay attention to their bodies and proactively engage in discussions with their physicians," says April Donahue, president of NOCC.
This consensus will facilitate a coordinated educational effort that will result in both physicians and women considering ovarian cancer when women experience these symptoms.
The National Ovarian Cancer Coalition is a 501 (c)(3) charitable organization that provides help and hope about ovarian cancer with public education and awareness, state divisions, a toll-free Help Line, comprehensive web site, peer support, publications and special projects. The National Ovarian Cancer Coalition's mission is to raise awareness and promote education about ovarian cancer.
The Gynecologic Cancer Foundation (GCF) is a non-profit organization whose mission is to ensure public awareness of gynecologic cancer prevention, early diagnosis and proper treatment. In addition, the Foundation supports research and training related to gynecologic cancers. GCF advances this mission by increasing public and private funds that aid in the development and implementation of programs to meet these goals.
National Ovarian Cancer Coalition
http://www.ovarian.org
Visit our ovarian cancer section for the latest news on this subject.
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Ovarian Cancer Symptoms
posted by Gregory D. Pawelski on 17 Jun 2007 at 2:17 pmThere is no consistently reliable, accurate screening test to detect ovarian cancer. For women known to be at a high risk for ovarian cancer, doctors use the blood test CA-125, as well as a pelvic exam and transvaginal ultrasound, to detect cancer. But the CA-125 test, though somewhat good at detecting recurrences of cancer, is not good enough by itself to screen the general population. Be mindful of blood clots (particularly if on estrogen replacement therapy). Certain cancers like ovarian can increase levels of substances that help blood clot.
One of the most promising new approaches that may deal with early detection of cancer is called Proteomics (Protein Expression Analysis), the study of proteins in the cells, tissues and body fluids. Even before a tumor can be felt, some researchers have found, the tumor begins secreting a distinctive pattern, or fingerprint of proteins. Here, you go beyond genes (DNA, the Genomic Analysis or structure of the human genome) and beyond Gene Expression (the measure of RNA content, like Her2/neu in breast cancer) to measure the actual proteins themselves.
Some scientists like to do stuff that they consider to be "cutting edge." There is a whole lot of high tech/cutting edge machinery which has been developed to look at Genomic Analysis (structure of the human genome) and Gene Expression Analysis (measuring RNA content), with Protein Expression Analysis (Proteonomics) and Disease Analysis (CT/PET scanning) moving in that direction. Disease Analysis has major limitations (requiring treating the patient to get data).
Protein Function Analysis (are proteins present, active or inactive) and Cell Function Analysis (cell culture testing) involve pretty old fashioned technologies and maximum "art." It takes a whole lot of hands on work and experience, which is why some scientists have screwed it up in the past (twenty years ago) and people have not been keen to get into it themselves. But it's like anything else relating to bioengineering, with enough time, attention to detail, experience, and effort, it is possible to make progress and to develop something which is useful.
The most important thing women can do is to take care of their health. Get to your doctor for a yearly exam. Your physician needs to see you when you are healthy and well in order to help dignose anything when there is a problem. Don't wait until it's too late.
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