BMJ Editor Condemns Scare Mongering Over Bird Flu
Main Category: Bird Flu / Avian FluArticle Date: 29 Jun 2007 - 1:00 PDT
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In this week's BMJ, Deputy Editor Tony Delamothe attacks the continued scare mongering over bird flu.
Somewhere, I imagine, there's a small group of people proud to be counted among the Friends of Avian Flu, or FAF for short, he writes. I suspect they have a catchy mission statement, such as "Keeping the nightmare alive," and lapel badges of vaguely bird-like shape.
Their challenge is to keep bird flu forever in the public eye. This should be getting harder, as influenza H5N1 is proving particularly resistant to undergoing the killer mutation that would allow efficient human to human transmission of the virus.
Ten years after the strain first appeared in humans, it has killed just 191 people, despite millions of people and poultry living in very close proximity in South East Asia. Although these deaths are a tragedy for the victims and their families, it's well to remember that a similar number of people die on the roads world wide every 84 minutes, he says.
Traditionally, we've blamed the drug companies for talking up the risks of diseases, or even inventing diseases, but this is not the case with bird flu. The track record of oseltamivir (Tamiflu) as a treatment for H5N1 is decidedly mixed. Yet FAF, he says, has incorporated this pharmaceutical failure into its story: for bird flu, The Drugs Don't Work. Be afraid. Be very afraid.
FAF also knows that the best way to generate column inches is high profile scientific conferences with well oiled media machines, and this week's BMJ reports some of the familiar observations from a conference, such as the inevitability of the pandemic and the possibility of drug resistance. But others, he says, were relatively new: the terminological mutation from "avian flu" to "pandemic flu," in recognition of H5N1's failure to mutate genetically.
While H5N1 had been groomed for stardom, the story has shifted: now any influenza strain can become pandemic, with further details unknown, he says.
As influenza pandemics occurred in 1918, 1957, and 1968, another one is likely. But, he asks, why should we be any more worried in 2007 than in 1997 or 2017? Couldn't those responsible for planning the next pandemic do their planning a little less publicly and put the frighteners on the rest of us at the appropriate time?
"Editor's Choice: FAFfing about"
http://www.bmj.com
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How To Prep For An Unknown
posted by Gaudia Ray on 29 Jun 2007 at 3:40 amBird Flu (as it appears all human flu starts in birds), and when in humans is termed Pandemic Flu, thus http://www.pandemicflu.gov, has 2 major aspects: severity and probability of occural. This creates a major dilemma, with an unsolvable preparatory response until the event facts are in place, and unsolvable then because the time window will probably be too short.
Fact: Flu transmits asymptomatically, with incubation being about 3 days during which time the R0 can vary quite dramatically, but the people infected have no knowledge that they have become ill.
Fact: A guesstimate by the CDC of duration will be 4 - 8 weeks, and with a goal of extending it much longer as this it is hoped will lower the time of crisis spike thereby allowing scarce health care resources to be spread over a longer period of time. The UK Pandemic Plan presents historical evidence that pandemics extend 16 - 17 weeks, and the reason it will be shorter this time is due to a belief that "modern medicine" and communications will raise consciousness and that human behavior will dramatically change from what it was and what it is.
Fact: Vaccine availability, under current technological ability, is reported to be in 12 to 24 weeks for the "first" amounts of vax to be distributed.
As you can see, when a pandemic occurs, its first wave will peak in 3 to 7 weeks, and it will be on its own ameliorating long before the first vax in response to that strain will ever begin to reach the public. So, we can expect no real help from vax during a pandemic.
Fact: H5N1 kills in an average of 8.5 days from first symptom appearance. H5N1 has spread during the past 2 years into nearly half the countries on this planet, most recently in Germany, this week. H5N1 has been found in pairings involving siblings, families, friends, healthcare workers, all with disease onset dates being 3 days apart which we know indicates human to human transmission, and which means that some strains of this virus are evolving into H2H communicable, and it's been found in family groupings
What is a rational response to the facts above? It's a simple question. If the pandemic is severe, like the mortality rates we have seen over the past 10 years, mortality rates that on the low side kill 40% and on the high side kill 85% of those infected (who have access to effective antivirals and hospital technology), then exposure to that pandemic level (with a CDC estimated 25-35% penetration into the population in each wave) would result in a quick breakdown in modern social services due to both the reality of infection itself in 25 - 35% of the population (a max of 20% of the populace all sick at one time), the need and desire to provide health care, and the impossible-to-avoid then-fear of exposure to a high virulence disease that kills so quickly.
The hoped for drop in virulence has not occured...yet. Neither has there been a dying out within the human populations. Instead, we are seeing modulating and sustained virulence levels, and we have seen the disease expanding its geographic inclusion. We in the USA are very fortunate as H5N1 is not yet identified in the Americas. But jet travel will bring it here when it becomes pandemic in any other country, asymptomatically.
It's up to you to decide if you want to prepare in advance. Clint Eastwood said, "Are you feeling lucky?" If you believe there will be easily available enough resources for you to store so you can weather the pandemic without exposure to others (that being the one sure way to avoid getting sick), then don't think anything further. If you think that a pandemic will interrupt the flow of water, fuel, food, electricity, phone, transportation services, then you may choose a different path than doing nothing.
The smartest flu experts have stocked up on non-comestible supplies to last them many months, and some have plans to protectively sequester; but they're probably too close to the developments of this flu, and they're biased as they believe what they see and what they project as experts in the field, and too many of those people believe H5N1 is a real and probable virus that will be more efficient in its infection in humans when it evolves further, so, they who think that H5N1 will pass over into our species are questionable roll models. Instead, like in hurricaine preparation, many will do nothing inspite of the real, measurable risks.
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