Stem cells transplanted to where your tooth fell out will soon make a new tooth for you

Main Category: Stem Cell Research
Article Date: 04 May 2004 - 0:00 PDT

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'Stem cells transplanted to where your tooth fell out will soon make a new tooth for you'

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Researchers in London have been awarded a grant of Ł500,000 ($820,000) to develop human teeth from stem cells. This could spell the end of dentures. The scientists who work at King's College London, UK, have set up a company called Odontis.

Odontis plans to research on humans in two years time. Its scientists have managed to grow new teeth in mice.

In this technique, if you lose a tooth, stem cells would be programmed to develop into teeth. They would then be transplanted into your jaw, where you lost tooth was (in the gap). Two months later you would have a brand new fully-developed tooth that you created yourself.

The scientists believe that if everything goes well, this technology could become available to the general public in about five years' time.

Humans have 32 teeth. In the UK most people over 50 have lost, on average, twelve teeth.

Professor Paul Sharpe, King's College London, said "A key advantage of our technology is that a living tooth can preserve the health of the surrounding tissues much better than artificial prosthesis. Teeth are living, and they are able to respond to a person's bite. They move and in doing so they maintain the health of the surrounding gums and teeth."

Experts believe the cost to the patient will be no more than what it costs now to have a synthetic implant.

Article adapted by Medical News Today from original press release.
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Visitor Opinions (latest shown first)

design intervention

posted by seaton on 3 Sep 2010 at 12:06 am

Hi there

I am researching for my final years industrial design project and have been researching tissue engineering as an emerging area

I am wondering what kind of products this type of technology, procedure and support system will require in the future????

any design ideas

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Teeth - titanium is forever

posted by Ken Arenson on 4 May 2004 at 2:30 am

"...a living tooth can preserve the health of the surrounding tissues much better than artificial prosthesis...", Professor Paul Sharpe.

Chronic gum disease is a condition of remission and exacerbation but it relentlessly loosens teeth over time by attacking connective ligamentous tissue that holds the tooth in place. If the tooth to be replaced by stem cell technology was lost to such disease, what will prevent the same disease from destroying ligamentous tissue around the new, living, tooth? Contrast that with the fact that the gum and bone tissue in which titanium implants are imbedded are resistant to recurrent gum disease, for reasons that are not yet elucidated. Although the bridge and superstructure wears out very fast, in my experience, the implants appear to last indefinitely, while stem cell teeth may be gone in a few years. Now, give me stem cells for teeth that are resistant to gum disease -- that would be the killer app.

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