Biospace Lab Announces A Technological Breakthrough In Molecular Imaging On Non-anesthetized Animals

Main Category: Pharma Industry / Biotech Industry
Also Included In: Veterinary
Article Date: 09 Oct 2007 - 4:00 PDT

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Biospace lab, molecular imaging company for pre- clinical research, is pleased to announce the first scientific publication on studies using the unique In Actio™ module, add-on to its Photon Imager optical imaging system. The study, entitled "Non-Invasive In Vivo Imaging of Calcium Signaling in Mice"* was conducted by biospace lab's collaborators from the Molecular Embryology Unit of the Institut Pasteur in Paris and the CEA-INSERM U803 team (Service Hospitalier Frédéric Joliot) at Orsay, France. Developed by biospace lab, the Photon Imager (F Imager) is an optical imaging system for in vivo bioluminescence and fluorescence studies. Based on a unique detection technology which allows photon counting techniques, the F Imager is the only system available for researchers that allows true real time imaging, and also the analysis of biological data on freely moving animals with its In Actio™ module.

"We are proud to offer this unique optical imaging technology to researchers worldwide, which opens the way to dynamical studies on non-anesthetized animals. The Photon Imager and its In Actio™ module represent a real technological innovation in comparison to tools that are currently available for the measurement and monitoring of molecular, genetic or cellular activity and bio-distribution in laboratory animals. With this system biospace lab consolidates its position as a leader on the in vivo imaging market" said Dr. Serge Maitrejean, COO of biospace lab.

A real technological breakthrough for in vivo bioluminescence and fluorescence studies, the F Imager is based on a unique detection technology which allows the counting of photons from ultraviolet to near infrared at a video frame rate. Researchers thus have much more spatial and temporal data on the biological signals emitted from the analyzed tissues. These data are particularly useful in the study of fast biological events, traditionally difficult to observe in vivo.

Dr. Bertrand Tavitian, Head of the CEA-INSERM U803 team at Orsay and co-author of the publication explained: "This non-invasive imaging technique opens new avenues for the analysis of Ca2+ signaling whenever whole body information in freely moving animals is desired, in particular during behavioural and developmental studies".

* The paper entitled "Non-Invasive In Vivo Imaging of Calcium signaling in Mice" is published on PLOS ONE and is accessible on line here.

Biospace Lab was founded in 1989 by Nobel Prize winner Georges Charpak to provide fellow researchers in biology with innovative imaging tools based on his discoveries in high-energy physics and particle detection. Since Then, Biospace has pursued and created strong links with the medical, pharmaceutical and scientific, communities to bring relevant and creative solutions to biomedical imaging needs.

Biospace lab focuses on high-performance imaging equipment for pre-clinical research in drug discovery and biology. The company has developed in this field a comprehensive portfolio of in vitro, in vivo and now in actio multimodality small animal imaging solutions used by almost every major pharmaceutical company and many prestigious academic centers worldwide.

Biospace lab headquarters, development and production facilities are located in central Paris, France and the company has a subsidiary in Cambridge, MA USA.

http://www.biospacelab.com

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