Stem Cell Innovations Cites Two Recent Government Documents Supporting The Use Of Cell-Based Assays For Toxicity Testing

Main Category: Stem Cell Research
Article Date: 25 Oct 2007 - 5:00 PDT

email to a friend   printer friendly   opinions  

Stem Cell Innovations (SCLL.OB) (SCI) noted that two recent government panels, one in the US and one in the UK, advocate the use of cell-based assays for toxicity testing. The Company's human liver-based ACTIVTox® and stem cell-based PluriCell™ systems are specifically designed for this purpose.

The National Research Council, part of the US National Academy of Sciences, published a report entitled "Toxicity Testing in the 21st Century: a Vision and a Strategy" promoting the use of cell-based models for toxicity testing. Another report entitled "Stem Cells in Predictive Toxicology", published by the Dept of Health and the Dept of Trade and Industry in the United Kingdom, specifically encouraged the establishment of stem cell-based assays to speed and standardize toxicity testing.

"These two reports, one in the US and one in the UK, affirm SCI's strategy of using human cell-based assays, rather than animal models, to assess toxicity in new drugs and chemicals,' said James H. Kelly, PhD, CEO of Stem Cell Innovations. "The UK report, in particular, cites liver, heart and neural models as the top priority, corresponding exactly to those established at SCI." The Company's ACTIVTox is a high throughput, human liver-based system used to identify and eliminate toxic liabilities in new drugs. It is currently available as either a kit or a service. Customers can run the assays in house or ship compounds to SCI for evaluation. The Company's PluriCell stem cell-based system is being used to develop both neural and cardiac models.

The NRC report can be found here. The UK Dept of Health report can be found clicking here.

About Stem Cell Innovations, Inc.

SCI is a cell biology company with an office in Scotch Plains, N.J., and facilities in Houston, TX. The Company's ACTIVTox system is a human liver based model for high throughput toxicity testing. Stem Cell Innovations proprietary, human pluripotent stem cells, known as PluriCells, have the potential to aid in drug discovery, toxicology, and cell therapy. Stem Cell Innovations is in the process of making its patented pluripotent cell lines, which are eligible for federal funding in the U.S., widely available to universities and other not-for-profit institutions to rapidly advance stem cell research.

Stem Cell Innovations is positioned to become a leading provider of toxicology testing and discovery systems for the pharmaceutical, chemical, and nutraceutical industries around the world. The development of the proprietary PluriCell technology greatly expands the Company's currently marketed ACTIVTox toxicology offerings.

Additional information is available at http:// www.stemcellinnovations.com.

ACTIVTox and PluriCells are Trademarks of Stem Cell Innovations, Inc.

Forward Looking Statement

This release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. The Private Securities Litigation Reform Act of 1995 provides a "safe harbor" for forward looking statements. Forward-Looking statements are not statements of historical facts, but rather reflect our current expectations concerning future events and results. We use words such as "expects", "intends", "believes", "may", "will" and "anticipates" to indicate forward-looking statements. Because these forward-looking statements involve risks and uncertainties, there are important factors that could cause actual results to differ materially from those expressed or implied by these forward-looking statements, including, but not limited to, those risks and uncertainties detailed in the Company's periodic reports filed with the Securities and Exchange Commission. We caution that these risk factors may not be exhaustive. We operate in a continually changing business environment, and new risk factors emerge from time to time. We cannot predict these new risk factors, nor can we assess the effect, if any, of the new risk factors on our business or the extent to which any factor or combination of factors may cause actual results to differ from those expressed or implied by these forward-looking statements.

If any one or more of these expectations and assumptions proves incorrect, actual results will likely differ materially from those contemplated by the forward-looking statements. Even if all of the foregoing assumptions and expectations prove correct, actual results may still differ materially from those expressed in the forward-looking statements as a result of factors we may not anticipate or that may be beyond our control. While we cannot assess the future impact that any of these differences could have on our business, financial condition, results of operations and cash flows or the market price of shares of our common stock, the difference could be significant. We do not undertake to update any forward-looking statements made by us, whether as a result of new information, future events or otherwise. You are cautioned.

http:// www.stemcellinnovations.com

• Additional
• References
• Citations