HPA Statement On Pseudomonas, UK
Main Category: Infectious Diseases / Bacteria / VirusesAlso Included In: Dermatology; Urology / Nephrology; Water - Air Quality / Agriculture
Article Date: 21 Nov 2007 - 1:00 PDT
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There has been some recent media interest in Pseudomonas infections . Pseudomonas are bacteria which are normally found in soil and ground water. Pseudomonas infections rarely affect healthy people and would be most likely to affect those who are already very sick.
The majority of Pseudomonas infections are treatable with antibiotics.
These bacteria can cause a range of infections from mild skin infections to urinary tract infections . They can also cause a variety of bloodstream infections , particularly in patients with serious burns and those who are severely immunosuppressed such as cancer and AIDS patients . Most infection cases are reported from intensive care, burns, spinal injuries or cancer units.
Pseudomonas infection may be spread by transfer of the bacteria from contaminated sources or medical equipment to patients. Unlike MRSA, Pseudomonas survives poorly on healthy skin and unlike Clostridium difficile is not a significant resident of the bowel and does not give rise to diarrhoea.
On occasion cross infection may occur between patients with Pseudomonas on a hospital ward or intensive care unit but often to a considerably lesser extent than that seen with MRSA and C difficile . Outbreaks of infection across and between hospitals are also very rare.
Actions to help prevent patients contracting Pseudomonas include effective hand hygiene, and good infection control measures.
It is not mandatory to report cases of Pseudomonas , however the Health Protection Agency monitors cases of blood poisoning which represent the serious end of the infection. In the last year, there were 3663 compared to 3306 reported in 2005.
The increased rate of reporting of cases of Pseudomonas is comparable to the increase seen for all blood poisoning via the HPA's voluntary surveillance scheme. The increase is partly due to better reporting, surveillance and testing and may also reflect a changing hospital population, with more patients who are vulnerable to infection through conditions which compromise their immune systems being treated.
For more information about Pseudomonas , see the HPA's website - click here.
http://www.hpa.org.uk
Visit our infectious diseases / bacteria / viruses section for the latest news on this subject.
MLA
15 Feb. 2012. <http://www.medicalnewstoday.com/releases/89441.php>
APA
http://www.medicalnewstoday.com/releases/89441.php.
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Infections Caused By Chemotherapy
posted by Gregory D. Pawelski on 21 Nov 2007 at 4:43 pmBacterial infections (with pseudomonas being a very common offender) have been a recognized risk of chemotherapy since the 1940's. In fact, the number one cause of chemotherapy-related mortality (save for the likely probability that it induces mutations in genetically unstable cancer cells to produce a more aggressive cancer cell) is infection, resulting from immunosupression. There are several mechanisms of immunosuppression, the most obvious being the predictable reduction in the white blood cell count following most forms of chemotherapy. The main justification of having medical oncology be a medical specialty unto itself is the expertise it requires to push the envelop with toxic drugs to kill the tumor without killing the patient. The second mechanism of immunosuppression is a reduction in lymphocytes and plasma cells, which also assist in fighting infections.
It's analogous to the old medical specialty of syphilology. There was a big medical specialty called syphilology which existed because of the expertise it took to give toxic cocktails of the various (mostly ineffective drugs). The formulas were quite complicated, but they persisted until the discovery of penicillin, which finally killed off not just the syphillis spirochete but also the specialty of siphilology. I would hopefully expect that something like this will happen with medical oncology, and I would be thrilled if it happened while I was still around to see it.
Source: http://www.poxhistory.com/
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