Lack Of Oxygen Is Probable Cause Of Infant Birthmarks

Main Category: Pediatrics / Children's Health
Also Included In: Pregnancy / Obstetrics;  Dermatology
Article Date: 08 Jan 2008 - 3:00 PDT

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A hemangioma is a benign tumor of cells that line blood vessels, appearing during the first few weeks of life as a large birthmark or lesion. A study published in Pediatric Dermatology reveals that a disturbance of oxygen depletion was found in placentas of babies who developed infantile hemangioma (IH).

Researchers reviewed placental samples from 26 pregnancies with babies who weighed less than 3.5 pounds, 13 consisting of newborns who developed IH after birth and 13 healthy preterm infants who did not have IH.

Only one of the infants without IH showed an abnormal placenta. The higher ratio of placental anomalies in babies with IH suggests that reduced oxygen to the placenta contributed to fetal stress, and that stress led to infantile hemangioma development.

"Our results suggest that disturbed placental circulation is a factor underlying the development of hemangiomas in very low weight newborns and indicates that placental examination is essential for clarifying the physiologic changes leading to IH in babies with normal birth weight," the authors conclude.

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This study is published in the journal Pediatric Dermatology.

Juan Carlos López Gutiérrez, M.D., Ph.D., is affiliated with La Paz Children's Hospital in Madrid.

Pediatric Dermatology answers the need for new ideas and strategies for today's pediatrician or dermatologist. As a teaching vehicle, the Journal is still unsurpassed and it will continue to present the latest on topics such as hemangiomas, atopic dermatitis, rare and unusual presentations of childhood diseases, neonatal medicine, and therapeutic advances.

Wiley-Blackwell was formed in February 2007 as a result of the acquisition of Blackwell Publishing Ltd. by John Wiley & Sons, Inc., and its merger with Wiley's Scientific, Technical, and Medical business. Together, the companies have created a global publishing business with deep strength in every major academic and professional field. Wiley-Blackwell publishes approximately 1,400 scholarly peer-reviewed journals and an extensive collection of books with global appeal. For more information on Wiley-Blackwell, please visit http://www.blackwellpublishing.com/ or http://interscience.wiley.com/.

Source: Amy Molnar
Blackwell Publishing Ltd.

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