Beyond The Abstract - The Value Of Combined Use Of Survivin, Cytokeratin 20 And Mucin 7 MRNA For Bladder Cancer Detection In Voided Urine

Main Category: Urology / Nephrology
Also Included In: Cancer / Oncology
Article Date: 20 Jan 2008 - 0:00 PDT

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UroToday.com - This study analyzed the clinical value of combined use of survivin, cytokeratin (CK) 20, and mucin (MUC) 7 mRNA in the detection of bladder cancer patients in China. The group evaluated these three markers in voided urine using traditional RT-PCR. It is confirmed that the overall sensitivity and specificity of the three markers were all higher than voided urine cytology. Combined the 3 markers with voided urine cytology gave a higher sensitivity than that of the biomarker alone. It may be a new choice for the detection of bladder cancer in urine combined using the three markers and may partly replace of the cystoscope.

Written by

Pu XY,MD, Wang ZP,MD, Chen YR, MD, Wang XH, MD, Wu YL, MD, and Wang HP, MD, as part of Beyond the Abstract on UroToday.com. This initiative offers a method of publishing for the professional urology community. Authors are given an opportunity to expand on the circumstances, limitations etc... of their research by referencing the published abstract.

Link to full abstract

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