Copyright 2009 Medical News Today Latest Acid Reflux / GERD News From Medical News Today. http://www.medicalnewstoday.com/sections/gerd/ admin@medicalnewstoday.com (MNT Admin) editors@medicalnewstoday.com (MNT Editors) en-us Wed, 04 Nov 2009 18:00:00 PST http://www.medicalnewstoday.com/articles/169848.php http://www.medicalnewstoday.com/articles/169848.php Catalent Pharma Solutions, one of the leading advanced drug delivery technology providers to the pharmaceutical industry, announced that the U.S. Food and Drug Administration (FDA) has granted marketing approval for Metozolv™ ODT (orally disintegrating tablets) metoclopramide HCL utilizing Catalent's Zydis® fast dissolve technology. Metozolv™ ODT was developed by Wilmington Pharmaceuticals and licensed to Salix Pharmaceuticals. Acid Reflux / GERD Mon, 02 Nov 2009 03:00:00 PST http://www.medicalnewstoday.com/articles/169467.php http://www.medicalnewstoday.com/articles/169467.php Despite being highly effective and beneficial for many patients, unexpected consequences are emerging in patients who are prescribed proton pump inhibitors (PPIs) for reflux diseases. Physicians are warned to monitor these effects and prescribe these medications carefully, according to a new commentary published in the November 2009 issue of Otolaryngology -Head and Neck Surgery. Acid Reflux / GERD Tue, 27 Oct 2009 05:00:00 PST http://www.medicalnewstoday.com/articles/168842.php http://www.medicalnewstoday.com/articles/168842.php Boston Medical Center (BMC) surgeons are now offering patients an incisionless alternative to laparoscopic and traditional surgery for treatment of acid reflux or GERD. Using the new procedure known as EsophyX TIF (Transoral Incisionless Fundaplication), surgeons can repair or reconstruct the valve between the esophagus and stomach, effectively stopping GERD. BMC is the only hospital in New England offering this new treatment. Acid Reflux / GERD Tue, 27 Oct 2009 01:00:00 PST http://www.medicalnewstoday.com/articles/168747.php http://www.medicalnewstoday.com/articles/168747.php In two new studies, presented at the American College of Gastroenterology's (ACG) 74th Annual Scientific meeting in San Diego, researchers explored the connection between high stress, high exposure occupations and long-term gastrointestinal disorders. GastroIntestinal / Gastroenterology Tue, 27 Oct 2009 01:00:00 PST http://www.medicalnewstoday.com/articles/168762.php http://www.medicalnewstoday.com/articles/168762.php New data being presented at the American College of Gastroenterology (ACG) 2009 Annual Scientific Meeting in San Diego showed that treatment with KAPIDEX(TM) (dexlansoprazole) delayed release capsules over a four-week period resulted in a statistically significant greater percentage of nights without heartburn in subjects with non-erosive gastroesophageal reflux disease (GERD), compared to placebo (p Acid Reflux / GERD Mon, 26 Oct 2009 01:00:00 PST http://www.medicalnewstoday.com/articles/168636.php http://www.medicalnewstoday.com/articles/168636.php Gastroesophageal reflux disease (GERD) is the most common esophageal disorder, and frequently encountered in the primary care setting. Accumulating evidence has confirmed the excellent efficacy and safety of proton pump inhibitor (PPI) therapy in patients with all grades of GERD, making these agents the mainstay of treatment. However, the possible impact of changes in body weight(BW) or body mass index (BMI) in reflux patients while on long-term PPI therapy has not been examined. Acid Reflux / GERD Wed, 21 Oct 2009 01:00:00 PST http://www.medicalnewstoday.com/articles/168056.php http://www.medicalnewstoday.com/articles/168056.php XenoPort, Inc. (Nasdaq:XNPT) announced today that it has initiated a Phase 2b clinical trial of arbaclofen placarbil (AP), also known as XP19986, in patients with gastroesophageal reflux disease (GERD) who remain symptomatic despite treatment with a proton pump inhibitor (PPI). The trial is a multi-center, randomized, double-blind, placebo-controlled study designed to assess the efficacy and safety of AP as adjunctive therapy to PPIs. Ronald W. Barrett, Ph.D. Acid Reflux / GERD Fri, 09 Oct 2009 00:00:00 PST http://www.medicalnewstoday.com/articles/166754.php http://www.medicalnewstoday.com/articles/166754.php H2 Blocker drugs, such as Famotidine, Cimetidine and Ranitidine, approved in the U.S. for acid reflux (heartburn), pose no significant risks for the fetus according to a large collaborative cohort study by researchers at Ben-Gurion University of the Negev. The study published in the Journal of Clinical Pharmacology provides significant reassurance for the safety of the fetus when H2 blocker drugs are given to women to relieve acid reflux during pregnancy. Acid Reflux / GERD Mon, 28 Sep 2009 02:00:00 PST http://www.medicalnewstoday.com/articles/165416.php http://www.medicalnewstoday.com/articles/165416.php Addex Pharmaceuticals (SWISS: ADXN), the allosteric modulation company, announced the completion of enrollment in the Phase IIb trial of ADX10059 as a monotherapy in patients with gastroesophageal reflux disease (GERD), the cause of heartburn and other symptoms. ADX10059 is a first-in-class reflux inhibitor that works by reducing activation of the metabotropic glutamate receptor 5 (mGluR5) through negative allosteric modulation (NAM). Acid Reflux / GERD Fri, 18 Sep 2009 01:00:00 PST http://www.medicalnewstoday.com/articles/164343.php http://www.medicalnewstoday.com/articles/164343.php Could medicines used for depression also treat chronic, severe indigestion? Scientists at Mayo Clinic suspect they can and, backed by funding from the National Institutes of Health (NIH), they are testing that premise in a nationwide clinical trial. "Nerve cells are found throughout the body, and just as their dysfunction in the brain can cause depression, we suspect overly sensitive nerves in the gut can produce this very uncomfortable indigestion," says Nicholas Talley, M.D., Ph. GastroIntestinal / Gastroenterology Tue, 15 Sep 2009 03:00:00 PST http://www.medicalnewstoday.com/articles/163911.php http://www.medicalnewstoday.com/articles/163911.php A popular stomach-acid reducer used to prevent stress ulcers in critically ill patients needing breathing machine support increases the risk of those patients contracting pneumonia threefold, according to researchers at Wake Forest University School of Medicine. Hospital-acquired pneumonia is the leading cause of infection-related deaths in critically ill patients. It increases hospital stays by an average of seven to nine days, cost of care, and the risk of other complications. GastroIntestinal / Gastroenterology Tue, 15 Sep 2009 02:00:00 PST http://www.medicalnewstoday.com/articles/163907.php http://www.medicalnewstoday.com/articles/163907.php Thomas Jefferson University Hospital is the first hospital in Philadelphia, and the Delaware Valley, offering endoluminal fundoplication (ELF) an incisionless surgical treatment option to provide long-term elimination of gastroesophageal reflux disease (GERD), one of the most common gastrointestinal diseases affecting hundreds of thousands of people, in which the esophagus becomes inflamed by digestive acid backing up from the stomach, resulting in heartburn. Acid Reflux / GERD Tue, 15 Sep 2009 00:00:00 PST http://www.medicalnewstoday.com/articles/163859.php http://www.medicalnewstoday.com/articles/163859.php The Pediatric Adolescent Gastroesophageal Reflux (PAGER) Association has been helping families learn about acid reflux since 1992. The medical name for the disease is gastroesophageal reflux. It means stomach + esophagus + backwash. "Acid reflux in children is often overlooked," says Beth Pulsifer-Anderson, Director of PAGER Association. Acid Reflux / GERD Thu, 10 Sep 2009 04:00:00 PST http://www.medicalnewstoday.com/articles/163497.php http://www.medicalnewstoday.com/articles/163497.php Fears about the cancer causing effects of the second most prescribed group of drugs in the Western world have been put to rest, following the largest ever study into their use. 'Proton pump inhibitors' (PPI) are the most commonly used treatment for chronic acid reflux, or 'heartburn', a painful burning sensation in the chest, neck and throat which is experienced by almost a third of people in developed countries. Acid Reflux / GERD Thu, 10 Sep 2009 00:00:00 PST http://www.medicalnewstoday.com/articles/163484.php http://www.medicalnewstoday.com/articles/163484.php Dyspepsia, also known as indigestion or upset stomach, is a term that describes discomfort or pain in the upper abdomen. It is not a disease. Dyspepsia is a group of symptoms which often include bloating, nausea and burping. Indigestion is usually caused by stomach acid coming into contact with the mucosa of the digestive system - the sensitive protective lining of the digestive system. GastroIntestinal / Gastroenterology Wed, 09 Sep 2009 04:00:00 PST http://www.medicalnewstoday.com/articles/163367.php http://www.medicalnewstoday.com/articles/163367.php Patients with upper gastrointestinal (GI) complaints visit their general practitioner (GP) more often than patients with other conditions. Researchers writing in the open access journal BMC Family Practice found that people with dyspepsia, heartburn, epigastric discomfort and other upper-abdominal complaints had almost twice as many GP contacts, which were ultimately associated with problems in all organ systems. Acid Reflux / GERD Tue, 08 Sep 2009 03:00:00 PST http://www.medicalnewstoday.com/articles/163239.php http://www.medicalnewstoday.com/articles/163239.php PEDIATRIC CHRONIC COUGH LINKED TO REFLUX AND ALLERGIES New research shows that chronic cough in children is most often caused by gastroesophageal reflux and allergies. Researchers from Tulane University in New Orleans, LA, evaluated 40 patients aged 5 to 12 years with chronic cough (> 8 weeks in duration) with no obvious cause. Each patient underwent extensive multispecialty testing. Respiratory / Asthma Wed, 02 Sep 2009 06:00:00 PST http://www.medicalnewstoday.com/articles/162691.php http://www.medicalnewstoday.com/articles/162691.php There has been much debate about the relationship between gastroesophageal reflux disease (GERD) and sleep. Three new studies in Clinical Gastroenterology and Hepatology explore GERD's effect on sleep quality and the health-care system as well as how a widely prescribed sleeping pill may mask the disease. Clinical Gastroenterology and Hepatology is the official journal of the American Gastroenterological Association (AGA) Institute. Acid Reflux / GERD Tue, 11 Aug 2009 05:00:00 PST http://www.medicalnewstoday.com/articles/160365.php http://www.medicalnewstoday.com/articles/160365.php Recently, the number of patients with GERD has increased in Japan. However, there have been few reports about the pathological findings in the esophageal squamous epithelium, and there are differing opinions among pathologists about the findings considered characteristic of chronic reflux esophagitis.　 Dr. Acid Reflux / GERD Sun, 09 Aug 2009 00:00:00 PST http://www.medicalnewstoday.com/articles/160159.php http://www.medicalnewstoday.com/articles/160159.php Surgery without an incision is now possible. Yesterday Goshen General Hospital and Drs. Mark Ranzinger and Norbert Schwer, of Gerig Surgical Associates and medical staff at Goshen General Hospital, became the first hospital and surgeons in Indiana to perform an incisionless surgery to treat heartburn. Acid Reflux / GERD Mon, 03 Aug 2009 00:00:00 PST http://www.medicalnewstoday.com/articles/159594.php http://www.medicalnewstoday.com/articles/159594.php Gastroesophageal reflux diseases , or GERD, affects about 10 million people in the United States, yet the cause and an unexpected increase in its prevalence over the last three decades remains unexplainable. Now, researchers have discovered that GERD is associated with global alteration of the microbiome in the esophagus. Acid Reflux / GERD Mon, 03 Aug 2009 00:00:00 PST http://www.medicalnewstoday.com/articles/159598.php http://www.medicalnewstoday.com/articles/159598.php Patient satisfaction with their medications and the quality of interactions with their doctor reflect the success of gastroesophageal reflux disease (GERD) therapy, according to a new study in Clinical Gastroenterology and Hepatology, the official journal of the American Gastroenterological Association (AGA) Institute. Acid Reflux / GERD Sat, 18 Jul 2009 01:00:00 PST http://www.medicalnewstoday.com/articles/157951.php http://www.medicalnewstoday.com/articles/157951.php FD, a common non-organic disease in the world, greatly affects a patient's quality of life. However, treatment of FD is still controversial and no single therapy is uniformly effective, due, in part, to absence of a reliable evaluation instrument. The Nepean Dyspepsia Index (NDI), measuring both symptom scores and impairment of the dyspepsia-specific health-related quality of life in FD patients, has been designed to diagnose FD and has been translated into several languages. Acid Reflux / GERD Fri, 17 Jul 2009 05:00:00 PST http://www.medicalnewstoday.com/articles/157944.php http://www.medicalnewstoday.com/articles/157944.php Expectant mothers who are obese are much more likely to suffer from minor complications such as heart burn and chest infections during pregnancy, a study suggests. Research by the University of Edinburgh found that obese mothers-to-be were nearly 10 times more likely to suffer from chest infections, and more than twice as likely to suffer from headaches and heartburn, compared with pregnant women of a healthy weight. Pregnancy / Obstetrics Mon, 13 Jul 2009 02:00:00 PST http://www.medicalnewstoday.com/articles/157268.php http://www.medicalnewstoday.com/articles/157268.php EndoGastric Solutions (EGS), the recognized leader in the emerging field of Natural Orifice Surgery (NOS), announced that the American Society of General Surgeons (ASGS) has published a position statement endorsing its Transoral Incisionless Fundoplication (TIF) procedure for the treatment of GERD. Acid Reflux / GERD