Copyright 2008 Medical News Today Latest Alzheimer's / Dementia News From Medical News Today. http://www.medicalnewstoday.com/sections/alzheimers/ admin@medicalnewstoday.com (MNT Admin) editors@medicalnewstoday.com (MNT Editors) en-us Tue, 13 May 2008 12:00:00 PDT http://www.medicalnewstoday.com/articles/107332.php Results of a US study of elderly men and women with a family history of Alzheimer's suggest that the nonsteroidal anti-inflammatory drugs (NSAIDs) naproxen and celecoxib did not improve cognitive function and the investigators recommended against using them to prevent Alzheimer's. Tue, 13 May 2008 03:00:00 PDT http://www.medicalnewstoday.com/articles/107180.php Your fate can be determined by tiny events. Imagine you live in the city and you walk everywhere to get exercise - you are healthy and not afraid of getting mugged. You almost never eat breakfast so you don't stop at the donut shop on the way to work, until one day the manager replaces the girl at the counter with her pretty red-haired younger sister. This seemingly unimportant change in your world is just enough to overcome your ability to resist high-fat temptation. Tue, 13 May 2008 01:00:00 PDT http://www.medicalnewstoday.com/articles/107172.php In terms of the number of people affected, neurological diseases that contributed to decline in neuronal function are sometimes considered the newest healthcare epidemic. With the number of cases of neurodegenerative conditions expected to grow dramatically, driven by the aging population in developed countries, this therapeutic area represents one of the most compelling in both commercial and human terms. Tue, 13 May 2008 01:00:00 PDT http://www.medicalnewstoday.com/articles/107127.php One in three people over 65 will die with dementia and too many of them are subjected to an undignified and unnecessarily painful death. This is often because staff lack the specialist training to provide good care at the end of someone's life. It is vital that all people, not just those with cancer, benefit from good palliative care. The number of people living with dementia in the UK is set to soar to more than a million in less than twenty years. Mon, 12 May 2008 03:00:00 PDT http://www.medicalnewstoday.com/articles/107049.php Research Highlights: Mechanism of action of compound found to induce neurotransmitter activity in brain cells The findings may lead researchers to develop potential novel therapies to treat Alzheimer's disease, amyotrophic lateral sclerosis, Huntington's disease, Mon, 12 May 2008 02:00:00 PDT http://www.medicalnewstoday.com/articles/106989.php "Obesity doubles the risk of Alzheimer's" is the headline in the Daily Express. It and other news sources report new research which found that people who are obese have an increased risk of all types of dementia. Being underweight "increased the risk of any kind of dementia by 36 per cent, while being obese increased it by 42 per cent. For Alzheimer's disease, being obese increased the risk by 80 per cent", the newspaper says. Fri, 09 May 2008 10:00:00 PDT http://www.medicalnewstoday.com/articles/106983.php Eisai Limited, the licence holder of Aricept® (donepezil hydrochloride) and Pfizer Limited, its co-promotion partner, announced today that the Court of Appeal has released its decision on the consequential issues arising from Court of Appeal's recent ruling that the process by which the National Institute for Health and Clinical Excellence (NICE) decided to restrict anti-dementia medicines for newly diagnosed patients with mild Alzheimer's disease was procedurally unfair. Fri, 09 May 2008 01:00:00 PDT http://www.medicalnewstoday.com/articles/106816.php Two projects by South Essex Partnership NHS Foundation Trust (SEPT) to promote dignity and independence for people who suffer from dementia were highly commended at this year's East of England Health and Social Care Awards. The innovative projects 'Lasting Memories' and 'My life Story' were launched in December 2007 and work closely with patients, their carers, families and friends to improve their quality of life. Fri, 09 May 2008 00:00:00 PDT http://www.medicalnewstoday.com/articles/106692.php A set of molecules found in certain plants appears to have a beneficial effect in brain tissue associated with Alzheimer's disease, according to a new study conducted in mice. The study was led by researchers at the University of South Florida and Cedars-Sinai Medical Center. An article in the Journal of Cellular and Molecular Medicine is available online.Terrence Town, Ph.D., one of the senior authors of the study, is available to provide more information about this study. Fri, 09 May 2008 00:00:00 PDT http://www.medicalnewstoday.com/articles/106690.php Obesity may increase adults' risk for having dementia, according to researchers at the Johns Hopkins Bloomberg School of Public Health. Their analysis of published obesity and dementia prospective follow-up studies over the past two decades shows a consistent relationship between the two diseases. The results are published by The International Association for the Study of Obesity in the May, 2008 issue of Obesity Reviews. Thu, 08 May 2008 03:00:00 PDT http://www.medicalnewstoday.com/articles/106755.php Alzheimer's disease (AD) is an incurable disease that is increasing in prevalence and will increase even more rapidly as the Baby Boom generation enters the age of highest risk. The available AD drugs are only partially effective in some patients. New strategies are urgently needed. Thu, 08 May 2008 02:00:00 PDT http://www.medicalnewstoday.com/articles/106658.php Samaritan Pharmaceuticals (OTCBB:SPHC), a biopharmaceutical company committed to commercializing new innovative therapeutic drugs, has received notification that the claims in the patent application for "Neuroprotective Spirostenol Pharmaceutical Compositions" covering Caprospinol (SP-233) have been allowed by the Australian Patent Office. The hallmark of Alzheimer's disease is plaque formation in areas of the brain that control memory and thinking skills. Thu, 08 May 2008 01:00:00 PDT http://www.medicalnewstoday.com/articles/106643.php Being obese can increase the risk of Alzheimer's Disease by as much as 80 percent, according to a study in the May issue of Obesity Reviews.But it's not just weight gain that poses a risk. People who are underweight also havean elevated risk of dementia, unlike people who are normal weight or overweight. Wed, 07 May 2008 03:00:00 PDT http://www.medicalnewstoday.com/articles/106536.php EPIX Pharmaceuticals, Inc. (NASDAQ:EPIX), a biopharmaceutical company focused on discovering and developing novel therapeutics through the use of its proprietary and highly efficient in silico drug discovery platform, today announced that it has begun its Phase 2b program in Alzheimer's disease through the initiation of a clinical trial of PRX-03140, its novel 5-HT4 agonist, in combination with donepezil (Aricept®). Tue, 06 May 2008 00:00:00 PDT http://www.medicalnewstoday.com/articles/106365.php Researchers in the US studying a large patient population have shown that use of the anti-inflammatory and painkiller ibuprofen is linked to lower risk of developing Alzheimer's disease. Patients who used the drug for more than 5 years were 40 per cent less likely to develop the disease compared with patients who did not use that type of drug at all. Mon, 05 May 2008 02:00:00 PDT http://www.medicalnewstoday.com/articles/106254.php Alzheimer's Society comment on new research suggesting tarenflurbil may be effective in halting symptoms of Alzheimer's disease, from the Lancet Neurology. 'This exciting clinical trial suggests a modification of a safe and readily available anti-inflammatory drug has a positive impact on memory and function for people with mild Alzheimer's disease. Mon, 05 May 2008 01:00:00 PDT http://www.medicalnewstoday.com/articles/106142.php The Court of Appeal ruled in favour of the drug companies Pfizer and Eisai, by finding that the National Institute for Health and Clinical Excellence (NICE) should have allowed public access to the health economics model used to determine the cost-effectiveness of key treatments in people with early stage Alzheimer's. Three judges found that the process by which NICE decided to restrict the anti-dementia medicines for newly diagnosed patients with mild Alzheimer's was procedurally unfair. Fri, 02 May 2008 05:00:00 PDT http://www.medicalnewstoday.com/articles/106123.php A study published in the May 1 issue of the journal SLEEP finds that sleep disturbances among Alzheimer patients vary significantly from those of their family caregivers, and that, surprisingly, poor sleep in either the patient or caregiver is not necessarily linked to disturbed sleep in the other.Susan M. Fri, 02 May 2008 04:00:00 PDT http://www.medicalnewstoday.com/articles/106105.php Alzheimer Scotland welcomes the recent findings from Professor Gordon Wilcock's randomised phase II trial of tarenflurbil in patients with mild to moderate Alzheimer's Disease, but cautions that the phase III stage will be crucial in ascertaining its true potential. The Oxford-based scientists, working with researchers across the world, found that there was a dose-related effect on measures of daily activities and function in patients with mild Alzheimer's Disease. Fri, 02 May 2008 02:00:00 PDT http://www.medicalnewstoday.com/articles/106053.php Eisai Limited, the licence holder of Aricept(R) (donepezil hydrochloride) and Pfizer Limited, its co-promotion partner, welcomed today's landmark ruling by the Court of Appeal. The Court found that the process by which the National Institute for Health and Clinical Excellence (NICE) decided to restrict anti-dementia medicines for newly diagnosed patients with mild Alzheimer's disease was procedurally unfair. Thu, 01 May 2008 16:00:00 PDT http://www.medicalnewstoday.com/articles/105887.php According to a study published in the Journal of NeurologyNeurosurgery and Psychiatry,men and women have different risk factors that contribute to thedevelopment of Alzheimer's disease and dementia. The French researchersfoundthat stroke is a main risk factor for men and depression is a criticalfactor for women.The researchers analyzed a sample of almost 7000 people over age 65from three French cities. Thu, 01 May 2008 12:00:00 PDT http://www.medicalnewstoday.com/articles/105988.php New research from France suggests that men and women have different risks for mild cognitive impairment (MCI) and progression to dementia. The researchers suggest stroke is a primary risk factor for men, and depression for women. Thu, 01 May 2008 02:00:00 PDT http://www.medicalnewstoday.com/articles/105938.php Diabetic individuals have a significantly higher risk of developing Alzheimer's disease but the molecular connection between the two remains unexplained. Now, researchers at the Salk Institute for Biological Studies identified the probable molecular basis for the diabetes - Alzheimer's interaction.In a study published in the current online issue of Neurobiology of Aging, investigators led by David R. Schubert, Ph.D. Wed, 30 Apr 2008 17:00:00 PDT http://www.medicalnewstoday.com/articles/105883.php An article published in The Lancet Neurologyrecommends a phase III study for the drug tarenflurbil, amedication given to patients with mild Alzheimer's disease (AD). Thephase II study found that patients who took 800 mg of tarenflurbiltwice daily had better functional ability results than patients takingplacebo. Wed, 30 Apr 2008 01:00:00 PDT http://www.medicalnewstoday.com/articles/105718.php The 23rd Colloque Medecine et Recherche of La Fondation Ipsen dedicated to the Alzheimer series was held in Paris on 28 April 2008. Entitled "Intracellular Traffic and Neurodegenerative Disorders" this meeting gathered fourteen leading researchers focused on the intracellular world.