Copyright 2008 Medical News Today Latest Cholesterol News From Medical News Today. http://www.medicalnewstoday.com/sections/cholesterol/ admin@medicalnewstoday.com (MNT Admin) editors@medicalnewstoday.com (MNT Editors) en-us Wed, 09 Jul 2008 01:00:00 PDT http://www.medicalnewstoday.com/articles/114307.php A great deal of scientific evidence shows that cholesterol-reducing medications known as statins can help prevent coronary artery disease. Although the safety of these medications has been well documented, as many as 40 percent of patients who receive a prescription for statins take the drug for less than one year. Tue, 08 Jul 2008 04:00:00 PDT http://www.medicalnewstoday.com/articles/114258.php The American Academy of Pediatrics has issued new cholesterol screening and treatment recommendations for children. The policy statement, "Lipid Screening and Cardiovascular Health in Childhood," recommends cholesterol screening of children and adolescents with a family history of high cholesterol or heart disease. It also recommends screening patients whose family history is unknown or those who have other factors for heart disease including obesity, high blood pressure or diabetes. Tue, 08 Jul 2008 03:00:00 PDT http://www.medicalnewstoday.com/articles/114223.php More and more people are aware of 'cholesterol' and how it increases the risk of heart disease. Some even know their cholesterol levels and may be controlling them through diet and lifestyle changes or with medication. Cholesterol is made in the liver and too much can cause arteries to fur up, but not all cholesterol is bad. Thu, 03 Jul 2008 02:00:00 PDT http://www.medicalnewstoday.com/articles/113803.php A new study from the UK suggests that low levels of the "good" HDL cholesterol is linked to poor memory, and decline in memory, in middle aged adults. The study is the work of researchers at University College, London, and is published in the 30th June issue of the Arteriosclerosis, Thrombosis and Vascular Biology journal of the American Heart Association. Thu, 03 Jul 2008 02:00:00 PDT http://www.medicalnewstoday.com/articles/113759.php Researchers at the University of Reading have found that an over-the-counter Artichoke Leaf Extract (ALE) from the globe artichoke plant can lower cholesterol in otherwise healthy individuals with moderately raised levels. Cardiovascular diseases are the chief causes of death in the UK, and are associated with raised circulating levels of total cholesterol in the plasma. Once plasma cholesterol reaches a certain level, drugs such as statins are often prescribed to help reduce it. Tue, 01 Jul 2008 07:00:00 PDT http://www.medicalnewstoday.com/articles/113484.php Low levels of high-density lipoproteins (HDL) - the "good" cholesterol - in middle age may increase the risk of memory loss and lead to dementia later in life, researchers reported in Arteriosclerosis, Thrombosis and Vascular Biology: Journal of the American Heart Association. Observing 3,673 participants (26.8 percent women) from the Whitehall II study, researchers found that falling levels of HDL cholesterol were predictors of declining memory by age 60. Tue, 01 Jul 2008 03:00:00 PDT http://www.medicalnewstoday.com/articles/113434.php One of the functions of High Density Lipoprotein (HDL) is to transport cholesterol from the arteries back to the liver to be degraded. It is clearly important to have enough of this transporter available. This study shows that if there is not enough High Density Lipoprotein to transport cholesterol and other lipids around the body, it can not only increase your risk of heart disease but also affect your memory and may increase your risk of getting Alzheimer's disease. Sat, 28 Jun 2008 00:00:00 PDT http://www.medicalnewstoday.com/articles/113176.php Almonds, as well as being high in vitamin E and other minerals, are also thought to have other health benefits, such as reducing cholesterol. Recently published work by the Institute of Food Research has identified potential prebiotic properties of almonds that could help improve our digestive health by increasing levels of beneficial gut bacteria. Our digestive system maintains large population of bacteria that live in the colon. Wed, 25 Jun 2008 11:00:00 PDT http://www.medicalnewstoday.com/articles/112753.php Spending on statins, drugs used to reduce artery-clogging cholesterol, increased 156 percent between 2000 and 2005, according to the latest News and Numbers from the federal Agency for Healthcare Research and Quality. Statins can reduce a person's risk of heart attack or stroke by lowering "bad" cholesterol and triglycerides, another fatty substance in the blood, and raising "good" cholesterol levels. Mon, 23 Jun 2008 02:00:00 PDT http://www.medicalnewstoday.com/articles/112368.php Pfizer Inc announced that it has entered into an agreement with generics manufacturer Ranbaxy Laboratories Ltd. of India and certain of its affiliates to settle substantially all their patent litigation worldwide involving Lipitor, the world's most-prescribed cholesterol-lowering medicine. Under the terms of the agreement, Ranbaxy will have a license to sell generic versions of Lipitor and Caduet in the United States effective November 30, 2011. Sun, 22 Jun 2008 02:00:00 PDT http://www.medicalnewstoday.com/articles/112228.php Next Pharmaceuticals announced the results of their placebo-controlled, randomized, double-blind clinical trial, which revealed multiple heart health benefits of Flavoxine. The published study concluded that Flavoxine significantly reduced LDL-cholesterol and triglycerides, while it significantly decreased blood pressure and fasting blood glucose. Wed, 18 Jun 2008 00:00:00 PDT http://www.medicalnewstoday.com/articles/111611.php A variation in the way the body processes a single protein may explain why some people don't respond well to drugs that lower "bad" cholesterol, according to a report in Circulation: Journal of the American Heart Association. The gene variation, called alternative splicing, explained 9 percent of the drugs' decreased power to reduce low-density lipoprotein (LDL) in study participants compared to people with the standard processing pathway. Tue, 17 Jun 2008 01:00:00 PDT http://www.medicalnewstoday.com/articles/111477.php Metabolex, Inc., a biopharmaceutical company focused on the discovery and development of proprietary new medicines for the treatment of metabolic diseases, announced that it has completed enrollment in a 180-patient Phase 2 trial of MBX-8025 in overweight or obese patients with high cholesterol and triglycerides. Sat, 14 Jun 2008 00:00:00 PDT http://www.medicalnewstoday.com/articles/111182.php Researchers have discovered an unknown regulator of fat and cholesterol production in the liver of mice, a significant finding that could lead to new therapies for lowering unhealthy blood levels of cholesterol and fats. Wed, 11 Jun 2008 01:00:00 PDT http://www.medicalnewstoday.com/articles/110647.php Incyte Corporation (Nasdaq:INCY) announced clinical results presented today at the American Diabetes Association 68th Scientific Sessions of its Phase IIa trial of INCB13739, an orally bioavailable inhibitor of the 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) enzyme. These results showed that 28 days of treatment with INCB13739 significantly improved hepatic insulin sensitivity and decreased plasma LDL- and total-cholesterol levels in patients with type 2 diabetes. Mon, 09 Jun 2008 14:00:00 PDT http://www.medicalnewstoday.com/articles/110455.php PanGenex Corporation (Pink Sheets: PGXC) announces the product launch of LIPIDEME™, an all-natural nutraceutical formulated with scientifically proven ingredients and the first product on the market to combine the triglyceride-lowering power of Omega-3 fatty acids with the cholesterol lowering ability of phytosterols and tocotrienols - plus the free-radical fighting capacity of Coenzyme Q10 (CoQ10). Dr. Eric J. Sat, 07 Jun 2008 11:00:00 PDT http://www.medicalnewstoday.com/articles/110205.php A research team has uncovered the likely target of niacin (vitamin B3) in the liver, which should provide a clearer picture of how this vitamin helps maintain adequate HDL-cholesterol levels in the blood and thus lower the risk of heart disease. While niacin can increase plasma HDL levels, the mechanism of how it works has been mysterious, although it's believed that niacin does not actually increase HDL production. Thu, 05 Jun 2008 00:00:00 PDT http://www.medicalnewstoday.com/articles/109833.php A new study in the June issue of Cell Metabolism, a Cell Press publication, sheds light on the action of the drug ezetimibe (trade name Zetia), which is used to treat high cholesterol. Ezetimibe is unique among cholesterol-lowering drugs in that it works by cutting the amount of cholesterol taken in from the diet rather than by blocking cholesterol's manufacture in the body. Wed, 28 May 2008 00:00:00 PDT http://www.medicalnewstoday.com/articles/108892.php Thanks to powerful cholesterol-lowering statin drugs, driving down low-density lipoprotein (LDL), or "bad" cholesterol, has been the primary approach to improving cholesterol levels. But there's more to the story of cholesterol and cardiovascular risk than LDL alone. Another key player is high-density lipoprotein (HDL), the "good" cholesterol. Higher levels of HDL are associated with lower cardiovascular risk. Wed, 21 May 2008 04:00:00 PDT http://www.medicalnewstoday.com/articles/108250.php University of Minnesota researchers have discovered that people with high oxidation levels of the low-density lipoprotein (LDL) particle that carries cholesterol throughout the blood are much more likely to develop metabolic syndrome - which can lead to a considerably increased risk of developing heart disease. Researchers measured oxidized LDL in more than 2,000 generally healthy people aged 33-45 (average age 40) in an ongoing study, called CARDIA. Sat, 17 May 2008 01:00:00 PDT http://www.medicalnewstoday.com/articles/107838.php Results of a new analysis of the Treating to New Targets (TNT) study show that intensive low-density lipoprotein (LDL) cholesterol-lowering in patients with stable coronary heart disease (CHD) whose systolic blood pressure was less than 140 mmHg reduced the risk of major cardiovascular events, including heart attack, stroke and resuscitated cardiac arrest, by 42 percent compared with less intensive LDL lowering and uncontrolled blood pressure of 140 mmHg or higher. Led by John B. Fri, 16 May 2008 03:00:00 PDT http://www.medicalnewstoday.com/articles/107609.php Poor cholesterol management may not only affect a man's risk for prostate cancer, but also his risk of biomedical recurrence after prostatectomy, according to new data from Duke University. Fri, 09 May 2008 01:00:00 PDT http://www.medicalnewstoday.com/articles/106815.php Randox produces high quality apolipoprotein tests for the diagnosis, monitoring and research of cardiovascular disease and related conditions. Apolipoproteins are essential components of lipoproteins, for example HDL and LDL, responsible for transporting cholesterol and triglycerides around the body. Six apolipoprotein tests are available from Randox: Apo A-I, Apo A-II, Apo B, Apo C-II, Apo C-III and Apo E. Thu, 08 May 2008 01:00:00 PDT http://www.medicalnewstoday.com/articles/106647.php LifeCycle Pharma A/S (OMX:LCP) announced positive results from the company's Phase II clinical program with LCP-AtorFen, a fixed-dose combination product of atorvastatin and fenofibrate for the treatment of mixed dyslipidemia. LCP-AtorFen is a convenient single tablet with a once-daily dosage profile and is without food effect. "The Phase II clinical program confirmed that LCP-AtorFen was safe and well-tolerated. Sat, 03 May 2008 02:00:00 PDT http://www.medicalnewstoday.com/articles/105948.php In polarized Caco-2 cells, cholesterol was depleted by a combination of synthesis inhibition and plasma membrane extraction with complexing agents. This led to an increased sorting of CEA to the basolateral surface. Interestingly, polarity was not significantly affected by this approach. The association of CEA to lipid rafts, cholesterol, and sphingolipid-enriched microdomains was inhibited in parallel. This study, performed by a team led by Dr.