Copyright 2010 Medical News TodayLatest Health News and Medical News posted throughout the day, every day.http://www.medicalnewstoday.com/sections/clinical_trials/admin@medicalnewstoday.com (MNT Admin)editors@medicalnewstoday.com (MNT Editors)en-us Tue, 09 Feb 2010 21:00:00 PSThttp://mnt.to/f/3xqthttp://mnt.to/f/3xqtKamada, a bio-pharmaceutical company engaged in the development, manufacturing and marketing of specialty life-saving therapeutics, announced today that it has enrolled the first patient into its pivotal clinical trial with its new breakthrough compound of inhaled alpha-1 antitrypsin (AAT) delivered by an Investigational eFlow Nebulizer System (PARI Pharma GmbH), in patients wi...Respiratory / Asthma Tue, 09 Feb 2010 11:00:00 PSThttp://mnt.to/f/3xq9http://mnt.to/f/3xq9Cerus Corporation (NASDAQ:CERS) announced today that its Phase 1 trial of red blood cells treated with the INTERCEPT Blood System met its primary endpoint, with preliminary analysis demonstrating that greater than 75 percent of treated cells continued to circulate 24 hours following transfusion...Blood / Hematology Tue, 09 Feb 2010 10:00:00 PSThttp://mnt.to/f/3xq8http://mnt.to/f/3xq8Psyadon Pharmaceuticals, Inc. announced that the United States Food and Drug Administration (FDA) has accepted its Investigational New Drug Application (IND) to study ecopipam in patients with Lesch-Nyhan Disease (LND). The first center at which the drug will be evaluated is Emory University under the direction of Dr. Hyder A. Jinnah, MD, PhD...Biology / Biochemistry Tue, 09 Feb 2010 06:00:00 PSThttp://mnt.to/f/3xpZhttp://mnt.to/f/3xpZDynavax Technologies Corporation (NASDAQ: DVAX) announced initiation of a large-scale Phase 3 trial designed to demonstrate the lot-to-lot consistency of commercial vaccine and to complete the safety database for HEPLISAV™, the Company's investigational adult hepatitis B vaccine...Liver Disease / Hepatitis Tue, 09 Feb 2010 04:00:00 PSThttp://mnt.to/f/3xpThttp://mnt.to/f/3xpTFewer prostate cancers were detected by prostate-specific antigen (PSA) screening in the U.S. than in a European randomized trial because of lower screening sensitivity, according to a new brief communication published online February 8 in the Journal of the National Cancer Institute. To compare the PSA screening performance in a clinical trial with that in a population setting, Elisabeth M...Prostate / Prostate Cancer Tue, 09 Feb 2010 02:00:00 PSThttp://mnt.to/f/3xnPhttp://mnt.to/f/3xnPNew research from the University of Alabama at Birmingham (UAB) says low potassium levels produce an increased risk of death or hospitalization in patients with heart failure and chronic kidney disease (CKD)...Heart Disease Tue, 09 Feb 2010 02:00:00 PSThttp://mnt.to/f/3xnRhttp://mnt.to/f/3xnRScientists have identified a gene they say is a strong candidate for involvement in premenstrual dysphoric disorder (PMDD) and other maladies associated with the natural flux in hormones during the menstrual cycle...Women's Health / Gynecology Tue, 09 Feb 2010 02:00:00 PSThttp://mnt.to/f/3xnThttp://mnt.to/f/3xnTCerebral palsy (CP) has increased in infants born prematurely in the United States, according to data presented by researchers from Loyola University Health System (LUHS). These findings were reported at the 30th Annual Meeting of the Society for Maternal-Fetal Medicine in Chicago. They also were published in the latest issue of the American Journal of Obstetrics & Gynecology...Neurology / Neuroscience Tue, 09 Feb 2010 02:00:00 PSThttp://mnt.to/f/3xnWhttp://mnt.to/f/3xnWA meta-analysis published in the current issue of Psychotherapy and Psychosomatics by Swiss investigators B. Metternich and associates indicates the effectiveness of non pharmacological interventions on memory complaints. Subjective memory complaints (SMC) in the absence of psychiatric or neurological disorders are common among older adults...Psychology / Psychiatry Tue, 09 Feb 2010 02:00:00 PSThttp://mnt.to/f/3xnYhttp://mnt.to/f/3xnYAn early stage clinical trial of the experimental drug dimebon (latrepirdine) in people with Huntington's disease appears to be safe and may improve cognition. That is the conclusion of a study published in the Archives of Neurology...Huntingtons Disease Tue, 09 Feb 2010 01:00:00 PSThttp://mnt.to/f/3xnvhttp://mnt.to/f/3xnvNovavax, Inc. (Nasdaq: NVAX) announced new data from a clinical study that began in May of 2009 among healthy adults 18 to 49 years of age with Novavax's trivalent seasonal influenza Virus-like Particle (VLP) vaccine. The vaccine matched the influenza strains recommended for the 2008-2009 influenza season including H1N1 A/Brisbane/59/2007, H3N2 A/Brisbane/10/2007, and B/Florida/04/2006 strains...Respiratory / Asthma Tue, 09 Feb 2010 01:00:00 PSThttp://mnt.to/f/3xnxhttp://mnt.to/f/3xnxGeoVax Labs, Inc. (OTC Bulletin Board: GOVX) (the "Company"), an Atlanta-based, biopharmaceutical company developing human vaccines for diseases caused by HIV-1 (Human Immunodeficiency Virus) and other infectious agents, provided an update on its vaccine trials progress...HIV / AIDS Tue, 09 Feb 2010 01:00:00 PSThttp://mnt.to/f/3xnChttp://mnt.to/f/3xnCCara Therapeutics, Inc. announced positive data in a Phase II proof-of-concept clinical trial of its peripherally-restricted kappa opioid agonist, CR845. The 46 patient Phase II, multi-center, double-blind, placebo-controlled study was conducted at eight hospitals in the United States and evaluated the efficacy and safety of CR845 in women following laparoscopic-assisted hysterectomy...Pain / Anesthetics Tue, 09 Feb 2010 01:00:00 PSThttp://mnt.to/f/3xnDhttp://mnt.to/f/3xnDPeople with anorexia nervosa, paradoxically, have strikingly high levels of fat within their bone marrow, report researchers at Children's Hospital Boston. Their findings, based on MRI imaging of the knees of 20 girls with anorexia and 20 healthy girls of the same age, appear in the February issue of the Journal of Bone and Mineral Research...Bones / Orthopaedics Tue, 09 Feb 2010 01:00:00 PSThttp://mnt.to/f/3xnFhttp://mnt.to/f/3xnFSagent Pharmaceuticals, Inc., a privately held specialty pharmaceutical company, announced that it has received FDA approval of labetalol hydrochloride (HCl) injection, USP, commonly used to control severe hypertension. The product will be available in two vial sizes 100 mg per 20 mL and 200 mg per 40 mL, multi-dose vials...Hypertension Tue, 09 Feb 2010 01:00:00 PSThttp://mnt.to/f/3xnGhttp://mnt.to/f/3xnGAmgen (Nasdaq: AMGN) announced that a pivotal, Phase 3, head-to-head trial evaluating denosumab versus Zometa® (zoledronic acid) in the treatment of bone metastases in 1,901 men with advanced prostate cancer met its primary and secondary endpoints...Prostate / Prostate Cancer Tue, 09 Feb 2010 01:00:00 PSThttp://mnt.to/f/3xnMhttp://mnt.to/f/3xnMA Mediterranean diet may help people avoid the small areas of brain damage that can lead to problems with thinking and memory, according to a study released that will be presented at the American Academy of Neurology's 62nd Annual Meeting in Toronto April 10 to April 17, 2010...Neurology / Neuroscience Mon, 08 Feb 2010 03:00:00 PSThttp://mnt.to/f/3xmxhttp://mnt.to/f/3xmx BioMedReports...Colorectal Cancer Mon, 08 Feb 2010 01:00:00 PSThttp://mnt.to/f/3xjhhttp://mnt.to/f/3xjhA new study of young children in orphanages in Bucharest, Romania, has found that children placed in foster care before age 2 were more apt to develop secure attachments to their foster parents than those who entered foster care after age 2...Pediatrics / Children's Health Mon, 08 Feb 2010 00:00:00 PSThttp://mnt.to/f/3xkmhttp://mnt.to/f/3xkmHigh-coverage human papillomavirus (HPV) vaccinations among adolescents and young women may result in a rapid reduction of genital warts, cervical cell abnormalities, and diagnostic and therapeutic procedures, researchers report in a new study published online in the Journal of the National Cancer Institute...Cervical Cancer / HPV Vaccine Sun, 07 Feb 2010 00:00:00 PSThttp://mnt.to/f/3xjvhttp://mnt.to/f/3xjvArQule, Inc...Colorectal Cancer Sun, 07 Feb 2010 00:00:00 PSThttp://mnt.to/f/3xjxhttp://mnt.to/f/3xjxBioheart, Inc., (OTCBB:BHRT) announced that the company has commenced work on its REGEN trial, a Phase I Clinical Trial to test genetically modified MyoCell® in patients suffering from Congestive Heart Failure (CHF). Bioheart's MyoCell® is a regenerative cell therapy that uses myoblasts, or muscle stem cells,that are grown from a patient's own muscle...Heart Disease Sun, 07 Feb 2010 00:00:00 PSThttp://mnt.to/f/3xjJhttp://mnt.to/f/3xjJThe U.S. Food and Drug Administration issued guidance on Bayesian statistical methods in the design and analysis of medical device clinical trials that could result in less costly and more efficient patient studies. The Bayesian statistical method applies an algorithm that makes it possible for companies to combine data collected in previous studies with data collected in a current trial...Medical Devices / Diagnostics Sat, 06 Feb 2010 01:00:00 PSThttp://mnt.to/f/3xjVhttp://mnt.to/f/3xjVSolvay Pharmaceuticals, Inc...Cystic Fibrosis Sat, 06 Feb 2010 01:00:00 PSThttp://mnt.to/f/3xjWhttp://mnt.to/f/3xjWIn a landmark study in children and teenagers with type 1 diabetes, JDRF-funded researchers at the University of Cambridge showed that using a first-generation artificial pancreas system overnight can lower the risk of low blood sugar emergencies while sleeping, and at the same time improve diabetes control...Diabetes