Copyright 2009 Medical News Today Latest Colorectal Cancer News From Medical News Today. http://www.medicalnewstoday.com/sections/colorectal_cancer/ admin@medicalnewstoday.com (MNT Admin) editors@medicalnewstoday.com (MNT Editors) en-us Sat, 14 Nov 2009 01:00:00 PST http://www.medicalnewstoday.com/articles/170932.php http://www.medicalnewstoday.com/articles/170932.php One difficulty with fighting cancer cells is that they are similar in many respects to the body's stem cells. By focusing on the differences, researchers at Karolinska Institutet have found a new way of tackling colon cancer. The study is presented in the prestigious journal Cell. Molecular signal pathways that stimulate the division of stem cells are generally the same as those active in tumour growth. Colorectal Cancer Sat, 14 Nov 2009 01:00:00 PST http://www.medicalnewstoday.com/articles/170968.php http://www.medicalnewstoday.com/articles/170968.php Researchers at the University of Wisconsin-Madison School of Medicine and Public Health have identified a molecular mechanism that allows two powerful signaling pathways to interact and begin a process leading to colorectal tumors. "We are very excited about these findings," says Vladimir Spiegelman, an associate professor of dermatology. "Drugs could be developed to block this mechanism and prevent colorectal cancer, which affects millions of people worldwide. Colorectal Cancer Sat, 14 Nov 2009 00:00:00 PST http://www.medicalnewstoday.com/articles/170904.php http://www.medicalnewstoday.com/articles/170904.php A compound in coffee has been found to be estrogenic in studies by Texas AgriLife Research scientists. Though the studies have not been conducted to determine recommended consumption amounts, scientists say the compound, called trigonelline or "trig," may be a factor in estrogen-dependent breast cancer but beneficial against colon cancer development. "The important thing to get from this is that 'trig' has the ability to act like a hormone," said Dr. Colorectal Cancer Fri, 13 Nov 2009 05:00:00 PST http://www.medicalnewstoday.com/articles/170922.php http://www.medicalnewstoday.com/articles/170922.php New research published in the November issue of the Journal of the American College of Surgeons shows that African-American patients with colorectal cancer are more likely to be diagnosed with advanced disease and are less likely to undergo surgical procedures compared with Caucasians, suggesting that improvements in screening and rates of operation may reduce differences in colorectal cancer outcomes for African-Americans. Colorectal Cancer Thu, 12 Nov 2009 00:00:00 PST http://www.medicalnewstoday.com/articles/170694.php http://www.medicalnewstoday.com/articles/170694.php An article published Online First and in The Lancet Oncology reports that optical diagnosis is a reliable method of correctly diagnosing small colorectal polyps during routine colonoscopy. This approach could be a more efficient and cost effective alternative to conventional histopathology. Therefore, optical diagnosis could replace formal histopathology for the diagnosis and management of most small polyps in routine clinical practice. Colorectal Cancer Wed, 11 Nov 2009 01:00:00 PST http://www.medicalnewstoday.com/articles/170501.php http://www.medicalnewstoday.com/articles/170501.php Laparoscopic surgery has been used in the treatment of intestinal disorders for close to 20 years, but its benefits have only recently begun to be extended to people with rectal cancer. Colorectal Cancer Fri, 06 Nov 2009 02:00:00 PST http://www.medicalnewstoday.com/articles/170041.php http://www.medicalnewstoday.com/articles/170041.php Amgen (Nasdaq: AMGN) announced that the Phase 3 PRIME "203" trial evaluating Vectibix® (panitumumab) administered in combination with FOLFOX (an oxaliplatin-based chemotherapy) as a first-line treatment of metastatic colorectal cancer (mCRC) failed to meet a secondary endpoint of overall survival. Colorectal Cancer Thu, 05 Nov 2009 05:00:00 PST http://www.medicalnewstoday.com/articles/169979.php http://www.medicalnewstoday.com/articles/169979.php Scientists are reporting development of a nano-size capsule that boosts the body's uptake of curcumin, an ingredient in yellow curry now being evaluated in clinical trials for treatment of several diseases. Their study is in ACS' Journal of Agricultural and Food Chemistry, a bi-weekly publication. Koji Wada and colleagues note that curcumin is a potent antioxidant found in the spice, turmeric. Nutrition / Diet Thu, 05 Nov 2009 00:00:00 PST http://www.medicalnewstoday.com/articles/169838.php http://www.medicalnewstoday.com/articles/169838.php The effectiveness of a screening colonoscopy may depend on the time of day it is performed. According to a new UCLA study, early-morning colonoscopies yielded more polyps per patient than later screenings, and fewer polyps were found hour by hour as the day progressed. The findings, published in the November issue of the journal Clinical Gastroenterology and Hepatology, point to the need for more research in this area to possibly improve outcomes for colonoscopy procedures. Colorectal Cancer Tue, 03 Nov 2009 00:00:00 PST http://www.medicalnewstoday.com/articles/169518.php http://www.medicalnewstoday.com/articles/169518.php GASTRO 2009 is the first joint world conference for gastroenterology and offers journalists the opportunity to obtain first hand expert information on the latest gastroenterology research and issues affecting the world today. GastroIntestinal / Gastroenterology Mon, 02 Nov 2009 04:00:00 PST http://www.medicalnewstoday.com/articles/169505.php http://www.medicalnewstoday.com/articles/169505.php GastroFISH™ is the first tissue-based fluorescence in situ hybridization (FISH) test for the detection of chromosomal anomalies associated with colon cancer. "We are excited to be the first laboratory to offer GastroFISH for the colon. Using current histological techniques, identifying adenomas with a high risk for progression to cancer is not possible. Colorectal Cancer Thu, 29 Oct 2009 02:00:00 PST http://www.medicalnewstoday.com/articles/169094.php http://www.medicalnewstoday.com/articles/169094.php High-definition (HD) colonoscopy is much more sensitive than standard colonoscopy in finding polyps that could morph into cancer, say researchers at the Mayo Clinic campus in Florida. Colorectal Cancer Thu, 29 Oct 2009 01:00:00 PST http://www.medicalnewstoday.com/articles/169070.php http://www.medicalnewstoday.com/articles/169070.php High-definition (HD) colonoscopy is much more sensitive than standard colonoscopy in finding polyps that could morph into cancer, say researchers at the Mayo Clinic campus in Florida. GastroIntestinal / Gastroenterology Wed, 28 Oct 2009 00:00:00 PST http://www.medicalnewstoday.com/articles/168875.php http://www.medicalnewstoday.com/articles/168875.php Drawing on years of experience in cancer research and patient care, The University of Texas M. D. Anderson Cancer Center have just released the most comprehensive, risk-based screening guidelines publicly available to date for breast, cervical and colorectal cancers. The new recommendations represent the first wave of an effort by M. D. Breast Cancer Wed, 28 Oct 2009 00:00:00 PST http://www.medicalnewstoday.com/articles/168879.php http://www.medicalnewstoday.com/articles/168879.php Researchers from Taiwan report in a new study that unsedated colonoscopy for primary colorectal cancer screening is well accepted in a majority of patients. Sedation is typically used for colonoscopy to make the patient feel comfortable during the procedure. In Taiwan, colonoscopy is performed less frequently than sigmoidoscopy for colorectal cancer screening due to concerns over cost and availability. Colorectal Cancer Wed, 28 Oct 2009 00:00:00 PST http://www.medicalnewstoday.com/articles/168890.php http://www.medicalnewstoday.com/articles/168890.php A Henry Ford Hospital study questions the need for aggressive screening for colonic polyps in patients with diverticulosis. The study sought to determine if asymptomatic patients with diverticular disease are at higher or lower risk for developing colonic polyps, abnormal growths found in the wall of the colon that sometimes become cancerous. GastroIntestinal / Gastroenterology Tue, 27 Oct 2009 05:00:00 PST http://www.medicalnewstoday.com/articles/168836.php http://www.medicalnewstoday.com/articles/168836.php Recent advances in colonoscopic technology are featured in a number of studies presented at the Annual Scientific Meeting of the American College of Gastroenterology this week. In this research some technologies fare better than others at improving detection of potentially pre-cancerous growths in the colon known as adenomas. Medical Devices / Diagnostics Tue, 27 Oct 2009 05:00:00 PST http://www.medicalnewstoday.com/articles/168837.php http://www.medicalnewstoday.com/articles/168837.php While there is little doubt concerning the effectiveness of colonoscopy procedures to detect colon cancer, a new study presented at the American College of Gastroenterology's 74th Annual Scientific Meeting in San Diego places new emphasis on the importance of adequate bowel preparation prior to procedure. Colorectal Cancer Tue, 27 Oct 2009 04:00:00 PST http://www.medicalnewstoday.com/articles/168820.php http://www.medicalnewstoday.com/articles/168820.php Although alcohol consumption has been linked to colon and breast cancer, exactly how this occurs remains unclear. A new study has found that epithelial-mesenchymal transition (EMT) - which is essential for numerous developmental processes - may also be a cellular pathway by which alcohol-induced cancer cells aggressively progress and metastasize. Colorectal Cancer Tue, 27 Oct 2009 02:00:00 PST http://www.medicalnewstoday.com/articles/168769.php http://www.medicalnewstoday.com/articles/168769.php In a review article published this month in The Oncologist, UNC's Dr. Richard M. Goldberg and a team of colleagues catalogue how the data collected in a single large comparative clinical trial testing combination chemotherapy for metastatic colorectal cancer has been used not only to benefit the patients that enrolled but also patients who subsequently developed the disease. Colorectal Cancer Tue, 27 Oct 2009 01:00:00 PST http://www.medicalnewstoday.com/articles/168751.php http://www.medicalnewstoday.com/articles/168751.php Recent advances in colonoscopic technology are featured in a number of studies presented at the Annual Scientific Meeting of the American College of Gastroenterology this week. In this research some technologies fare better than others at improving detection of potentially pre-cancerous growths in the colon known as adenomas. Colorectal Cancer Tue, 27 Oct 2009 01:00:00 PST http://www.medicalnewstoday.com/articles/168755.php http://www.medicalnewstoday.com/articles/168755.php Three studies presented this week at the American College of Gastroenterology's 74th Annual Scientific meeting in San Diego underscore the growing disparities in gastrointestinal disease, particularly colon cancer and Barrett's Esophagus, among certain ethnic and gender populations, including African Americans, Latinos and women. GastroIntestinal / Gastroenterology Mon, 26 Oct 2009 18:00:00 PST http://www.medicalnewstoday.com/articles/168726.php http://www.medicalnewstoday.com/articles/168726.php African Americans are at significantly higher risk of developing colorectal cancer, and being diagnosed with the disease at a later stage, than other ethnic groups. That's the finding of a paper being presented at the annual meeting of the American College of Gastroenterology in San Diego. Robert Wong, M.D. Colorectal Cancer Thu, 22 Oct 2009 06:00:00 PST http://www.medicalnewstoday.com/articles/168346.php http://www.medicalnewstoday.com/articles/168346.php Cancer cells fueled by the mutant KRAS oncogene, which makes them notoriously difficult to treat, can be killed by blocking a more vulnerable genetic partner of KRAS, report scientists at the Dana-Farber Cancer Institute and the Broad Institute of Harvard and MIT. Pancreatic Cancer Wed, 21 Oct 2009 03:00:00 PST http://www.medicalnewstoday.com/articles/168100.php http://www.medicalnewstoday.com/articles/168100.php Current research suggests that latent cytomegalovirus (CMV) infection may exacerbate inflammatory bowel disease (IBD). The related report by Onyeagocha et al, "Latent cytomegalovirus infection exacerbates experimental colitis," appears in the November 2009 issue of The American Journal of Pathology. CMV infects between 50% and 80% of adults in the United States. Irritable-Bowel Syndrome