Copyright 2010 Medical News TodayLatest Health News and Medical News posted throughout the day, every day.http://www.medicalnewstoday.com/sections/crohns/admin@medicalnewstoday.com (MNT Admin)editors@medicalnewstoday.com (MNT Editors)en-us Mon, 08 Feb 2010 02:00:00 PSThttp://mnt.to/f/3xm9http://mnt.to/f/3xm9Although inflammatory bowel disease (IBD) [comprising mainly Crohn's disease (CD) and ulcerative colitis (UC)] is thought to affect about 150 000 people in the United Kingdom, the prevalence of severe IBD is not known. Mortality following hospitalization for IBD is significant but little has been reported on long-term follow-up...Crohn's Fri, 29 Jan 2010 00:00:00 PSThttp://mnt.to/f/3wVphttp://mnt.to/f/3wVpA new study has found that Vitamin D, readily available in supplements or cod liver oil, can counter the effects of Crohn's disease...Crohn's Wed, 20 Jan 2010 04:00:00 PSThttp://mnt.to/f/3wy5http://mnt.to/f/3wy5Bacteria that produce compounds to reduce inflammation and strengthen host defences could be used to treat inflammatory bowel disease (IBD). Such probiotic microbes could be the most successful treatment for IBD to date, as explained in a review published in the February issue of the Journal of Medical Microbiology...Crohn's Tue, 12 Jan 2010 01:00:00 PSThttp://mnt.to/f/3w99http://mnt.to/f/3w99GlaxoSmithKline (GSK) and ChemoCentryx, Inc. announced that GSK has exercised its option to obtain an exclusive license for further development and worldwide commercialization of Traficet-EN(TM) (CCX282-B), a specific CCR9 antagonist with the potential to offer a new approach for the treatment of inflammatory bowel diseases, including Crohn's disease...Crohn's Wed, 06 Jan 2010 01:00:00 PSThttp://mnt.to/f/3vXYhttp://mnt.to/f/3vXYRobarts Clinical Trials at The University of Western Ontario in London, Canada, has been awarded a 4.7 million dollar grant to conduct a randomized controlled trial evaluating treatment options for Crohn's disease. The outcome is expected to lead to a more streamlined treatment path and better disease management for patients...Crohn's Mon, 14 Dec 2009 01:00:00 PSThttp://mnt.to/f/3vrJhttp://mnt.to/f/3vrJCanadian researchers have discovered a novel molecular mechanism that prevents cancer...Cancer / Oncology Wed, 02 Dec 2009 02:00:00 PSThttp://mnt.to/f/3tVThttp://mnt.to/f/3tVTMarla C. Dubinsky, M.D., director of the Cedars-Sinai Pediatric Inflammatory Bowel Disease Center and one of the world's leading researchers studying the disease, has been named the Abe and Claire Levine Chair in Pediatric Inflammatory Bowel Disease. The endowed chair, presented in November, will fund continuing research to find groundbreaking new treatments for IBD...Crohn's Thu, 26 Nov 2009 02:00:00 PSThttp://mnt.to/f/3tKDhttp://mnt.to/f/3tKDChemoCentryx, Inc., announced that Phase II/III clinical data from the Company's PROTECT-1 (the Prospective Randomized Oral Therapy Evaluation in Crohn's disease Trial) of Traficet-EN(TM) (CCX282-B) in patients with moderate-to-severe Crohn's disease demonstrated clinical efficacy with a favorable safety and tolerability profile...Crohn's Wed, 18 Nov 2009 04:00:00 PSThttp://mnt.to/f/3tnXhttp://mnt.to/f/3tnXResearch into the controversial drug thalidomide reveals that the mechanism through which the drug causes limb defects is the same process which causes it to damage internal organs and other tissues...Vascular Wed, 28 Oct 2009 15:00:00 PSThttp://mnt.to/f/3sqphttp://mnt.to/f/3sqpElan Corporation, plc (NYSE: ELN) and Biogen Idec (NASDAQ: BIIB) announced data showing that treatment with TYSABRI® (natalizumab) significantly reduced the rate of hospitalization compared with placebo in patients with moderate - to - severe Crohn's disease during both induction and maintenance treatment...Crohn's Mon, 26 Oct 2009 03:00:00 PSThttp://mnt.to/f/3sgkhttp://mnt.to/f/3sgkThe probiotic, Bacillus polyfermenticus, can help mice recover from colitis, a new study has found. Mice treated with B. polyfermenticus during the non-inflammatory period of the disease had reduced rectal bleeding, their tissues were less inflamed and they gained more weight than mice that did not receive the treatment...Nutrition / Diet Sat, 17 Oct 2009 01:00:00 PSThttp://mnt.to/f/3rRqhttp://mnt.to/f/3rRqPersistent inflammation and the activation of the immune system is the key pathological mechanism affecting many long-term conditions, such as rheumatoid arthritis, psoriasis, ulcerative colitis, and Crohn's disease and is the predominant mechanism underlying organ transplant rejection...Immune System / Vaccines Sat, 10 Oct 2009 00:00:00 PSThttp://mnt.to/f/3rxthttp://mnt.to/f/3rxtNew findings related to an uncommon genetic disorder may impact the diagnosis and treatment of inflammatory bowel disease (IBD), the most common chronic gastrointestinal illness in children and teens. Two million Americans have IBD which involves inflammation of the gastrointestinal tract...GastroIntestinal / Gastroenterology Thu, 08 Oct 2009 00:00:00 PSThttp://mnt.to/f/3rpwhttp://mnt.to/f/3rpwA bacterium possibly linked to Crohn's disease could be lurking in wild animals. According to research published in the open access journal BMC Microbiology, Mycobacterium avium subspecies paratuberculosis (Map), can be transmitted between wildlife and domestic ruminants, supporting the theory of wildlife reservoirs of infection...Crohn's Tue, 29 Sep 2009 08:00:00 PSThttp://mnt.to/f/3qYghttp://mnt.to/f/3qYgBowel incontinence, also known as fecal (UK: faecal) incontinence, is an inability to control bowel movements. The person's stools (feces) leak from the rectum uncontrollably. Bowel incontinence can vary in severity from passing a small amount of feces when breaking wind, to total loss of bowel control...GastroIntestinal / Gastroenterology Sat, 12 Sep 2009 00:00:00 PSThttp://mnt.to/f/3qdjhttp://mnt.to/f/3qdjUlcerative colitis is a fairly common chronic (long-term) disease that causes inflammation of the colon (the large intestine). It is a form of inflammatory bowel disease that has some similarity to Crohn's disease, a related disorder. The colon - or large intestine - removes nutrients form undigested food and gets rid of waste products through the rectum and anus when we pass feces (stools)...GastroIntestinal / Gastroenterology Thu, 27 Aug 2009 05:00:00 PSThttp://mnt.to/f/3pxchttp://mnt.to/f/3pxcAnti-microbial antibody formation has been reported in celiac disease. Relatively high positivity rates were observed for the conventional antibodies, for example, ASCA, anti-OmpW, and anti-I2, and they were known to decrease after a successful gluten free-diet...Allergy Tue, 18 Aug 2009 01:00:00 PSThttp://mnt.to/f/3p2Ghttp://mnt.to/f/3p2GThe U.S. Food and Drug Administration is requiring stronger warnings in the prescribing information for a class of drugs known as TNF blockers...Pediatrics / Children's Health Tue, 11 Aug 2009 05:00:00 PSThttp://mnt.to/f/3nNKhttp://mnt.to/f/3nNKUsing the Vienna classification system, it has been shown in clinic-based cohorts that there can be a significant change in disease behavior over time, whereas disease location remains relatively stable. Clinical and environmental factors as well as medical therapy might be relevant in predicting disease behavior change in patients with CD...Crohn's Thu, 23 Jul 2009 14:00:00 PSThttp://mnt.to/f/3n5shttp://mnt.to/f/3n5sDiarrhea is the frequent passing of loose or watery stools. Acute diarrhea, which is a common cause of death in developing countries, appears rapidly and may last from five to ten days. Chronic diarrhea lasts much longer and is the second cause of childhood death in the developing world. Diarrhea is sometimes accompanied by abdominal cramps or fever...GastroIntestinal / Gastroenterology Sat, 11 Jul 2009 00:00:00 PSThttp://mnt.to/f/3msBhttp://mnt.to/f/3msBTwenty-five per cent of Crohn's disease patients have a mutation in what is called the NOD2 gene, but it is not precisely known how this mutation influences the disease. The latest study by Dr. Marcel Behr, of the Research Institute of the MUHC and McGill University, has provided new insight into how this might occur. The study was published on July 9th in the Journal of Experimental Medicine...Crohn's Sat, 11 Jul 2009 00:00:00 PSThttp://mnt.to/f/3msMhttp://mnt.to/f/3msMResearchers from Case Western Reserve University School of Medicine identified a novel link between ITCH, a gene known to regulate inflammation in the body and NOD2, a gene which causes the majority of genetic Crohn's Disease diagnoses...Crohn's Thu, 02 Jul 2009 00:00:00 PSThttp://mnt.to/f/3kZJhttp://mnt.to/f/3kZJTreatment with anti-tumor necrosis factor (TNF) agents is recognized as a risk factor for tuberculosis (TB) in patients with immune-mediated inflammatory diseases such as rheumatoid arthritis, ankylosing spondylitis, Crohn's disease, psoriatic arthritis and psoriasis...Tuberculosis Thu, 18 Jun 2009 12:00:00 PSThttp://mnt.to/f/3kpchttp://mnt.to/f/3kpcGastroenteritis means irritation and inflammation of the gastrointestinal tract, which includes the stomach and small and large intestines. The condition is usually due to bacteria, food poisoning, parasites, or viruses, and it often results in diarrhea, abdominal pain, nausea, and vomiting...GastroIntestinal / Gastroenterology Sun, 14 Jun 2009 00:00:00 PSThttp://mnt.to/f/3k3bhttp://mnt.to/f/3k3bGiven Imaging Ltd...GastroIntestinal / Gastroenterology