Copyright 2009 Medical News Today Latest Crohn's News From Medical News Today. http://www.medicalnewstoday.com/sections/crohns/ admin@medicalnewstoday.com (MNT Admin) editors@medicalnewstoday.com (MNT Editors) en-us Thu, 02 Jul 2009 00:00:00 PDT http://www.medicalnewstoday.com/articles/156050.php http://www.medicalnewstoday.com/articles/156050.php Treatment with anti-tumor necrosis factor (TNF) agents is recognized as a risk factor for tuberculosis (TB) in patients with immune-mediated inflammatory diseases such as rheumatoid arthritis, ankylosing spondylitis, Crohn's disease, psoriatic arthritis and psoriasis. Most TB cases develop as a result of reactivation of a latent TB infection, and health authorities worldwide recommend screening for latent TB and treating patients before initiating anti-TNF treatment. Tuberculosis Thu, 18 Jun 2009 12:00:00 PDT http://www.medicalnewstoday.com/articles/154555.php http://www.medicalnewstoday.com/articles/154555.php Gastroenteritis means irritation and inflammation of the gastrointestinal tract, which includes the stomach and small and large intestines. The condition is usually due to bacteria, food poisoning, parasites, or viruses, and it often results in diarrhea, abdominal pain, nausea, and vomiting. Gastroenteritis is commonly called gastric flu or stomach flu although it has no relation to the influenza virus. GastroIntestinal / Gastroenterology Sun, 14 Jun 2009 00:00:00 PDT http://www.medicalnewstoday.com/articles/153721.php http://www.medicalnewstoday.com/articles/153721.php Given Imaging Ltd. (NASDAQ: GIVN) announced a new study that shows over half of the eligible patients with occult or obscure gastrointestinal bleeding (OGIB) may benefit from the additional diagnostic information provided by small bowel capsule endoscopy in accordance with existing gastrointestinal (GI) society guidelines, which call for the patient-friendly, non-invasive procedure following a negative upper endoscopy and colonoscopy. GastroIntestinal / Gastroenterology Mon, 08 Jun 2009 09:00:00 PDT http://www.medicalnewstoday.com/articles/152995.php http://www.medicalnewstoday.com/articles/152995.php When pouches begin to protrude outwards from the colon wall the person has diverticular disease or diverticulosis. When one of these pouches becomes infected and inflamed, that infection is called diverticulitis. People may have lots of protruding pouches and feel fine. However, when one of them becomes infected it can be very painful. Recap - What is the difference between diverticulitis, diverticulosis and diverticular disease? 1. GastroIntestinal / Gastroenterology Mon, 08 Jun 2009 01:00:00 PDT http://www.medicalnewstoday.com/articles/152920.php http://www.medicalnewstoday.com/articles/152920.php Given Imaging Ltd. (NASDAQ: GIVN) announced a new study that shows over half of the eligible patients with occult or obscure gastrointestinal bleeding (OGIB) may benefit from the additional diagnostic information provided by small bowel capsule endoscopy in accordance with existing gastrointestinal (GI) society guidelines, which call for the patient-friendly, non-invasive procedure following a negative upper endoscopy and colonoscopy. GastroIntestinal / Gastroenterology Thu, 04 Jun 2009 06:00:00 PDT http://www.medicalnewstoday.com/articles/152595.php http://www.medicalnewstoday.com/articles/152595.php Enzo Biochem, Inc. (NYSE: ENZ), a biotechnology company specializing in gene identification and genetic and immune regulation technologies for diagnostic and therapeutic applications and laboratory services, announced that data from a Phase II clinical trial was presented today at Digestive Disease Week, the largest international gathering of academic researchers and practicing physicians in gastrointestinal medicine, held this year in Chicago. Crohn's Wed, 03 Jun 2009 05:00:00 PDT http://www.medicalnewstoday.com/articles/152439.php http://www.medicalnewstoday.com/articles/152439.php Researchers at Penn State College of Medicine, working with biochemists, geneticists and clinicians at the University of Bern, Switzerland and in the United Kingdom, have discovered an enzyme that has a key role in inflammatory bowel disease (IBD). The team, co-led by Judith Bond, Ph.D. Crohn's Wed, 03 Jun 2009 04:00:00 PDT http://www.medicalnewstoday.com/articles/152422.php http://www.medicalnewstoday.com/articles/152422.php Monoclonal antibodies can be safely and successfully used for the treatment of several gastroenterological disorders according to data being presented at Digestive Disease Week® (DDW®) 2009. DDW is the largest international gathering of physicians and researchers in the field of gastroenterology, hepatology, endoscopy and gastrointestinal surgery. GastroIntestinal / Gastroenterology Wed, 03 Jun 2009 01:00:00 PDT http://www.medicalnewstoday.com/articles/152332.php http://www.medicalnewstoday.com/articles/152332.php ChemoCentryx, Inc. Crohn's Wed, 03 Jun 2009 00:00:00 PDT http://www.medicalnewstoday.com/articles/152322.php http://www.medicalnewstoday.com/articles/152322.php New long-term findings from the Phase 3b study of patients with moderately to severely active Crohn's disease having inadequate response to conventional therapies, but naive to immunomodulators and biologic therapy, were presented at Digestive Disease Week today. Data from the SONIC study showed that a greater proportion of patients receiving REMICADE (infliximab) maintained steroid-free remission at one year, compared with patients receiving azathioprine alone. Crohn's Tue, 02 Jun 2009 04:00:00 PDT http://www.medicalnewstoday.com/articles/152200.php http://www.medicalnewstoday.com/articles/152200.php Health outcomes explored at DDW 2009 Researchers are making great strides in understanding the development and treatment of inflammatory bowel disease, a chronic inflammatory condition of the digestive tract that affects more than a half million Americans, according to several studies being presented at Digestive Disease Week® 2009 (DDW®). GastroIntestinal / Gastroenterology Thu, 28 May 2009 03:00:00 PDT http://www.medicalnewstoday.com/articles/151620.php http://www.medicalnewstoday.com/articles/151620.php Crohn's disease is an ongoing condition that causes inflammation of the digestive tract, or the GI (gastrointestinal) tract (the gut). Crohn's disease may also be called ileitis or enteritis. Crohn's disease can affect any part of the gut, from the mouth all the way down to the anus. In the majority of cases the lower part of the small intestine - the ileum - is affected. Patients with Crohn's disease can feel pain; the condition makes the intestines empty frequently, resulting in diarrhea. Crohn's Fri, 22 May 2009 08:00:00 PDT http://www.medicalnewstoday.com/articles/151040.php http://www.medicalnewstoday.com/articles/151040.php WellApps, Inc. launched an iPhone application to help people with (IBD) Crohn's and Ulcerative Colitis provide accurate symptom data to their doctors for optimal treatment. The application, called GI Monitor , was developed by an 18-year Crohn's patient after a recent flare up of his condition. Inspired by a long battle with Crohn's disease, 34-year old Brett Shamosh, a Digital Media Executive from Bergen County, NJ, decided to use technology to help fellow IBD patients. Crohn's Wed, 20 May 2009 01:00:00 PDT http://www.medicalnewstoday.com/articles/150676.php http://www.medicalnewstoday.com/articles/150676.php ChemoCentryx, Inc., announced that data from the company's PROTECT-1 (the Prospective Randomized Oral Therapy Evaluation in Crohn's disease Trial) Phase II/III clinical trial of Traficet-EN(TM) (CCX282-B) in patients with moderate-to-severe Crohn's disease will be presented in an oral session at the upcoming 2009 Digestive Disease Week (DDW) meeting. Crohn's Sat, 16 May 2009 02:00:00 PDT http://www.medicalnewstoday.com/articles/150307.php http://www.medicalnewstoday.com/articles/150307.php UCB announced that Cimzia(R) (certolizumab pegol), the only PEGylated anti-TNF (Tumor Necrosis Factor) approved in the U.S. Crohn's Wed, 29 Apr 2009 04:00:00 PDT http://www.medicalnewstoday.com/articles/148058.php http://www.medicalnewstoday.com/articles/148058.php Scientists at The University of Nottingham are investigating whether stem cell markers could have a role to play in speeding up wound healing in patients suffering from inflammatory bowel disease (IBD). Stem Cell Research Fri, 24 Apr 2009 07:00:00 PDT http://www.medicalnewstoday.com/articles/147400.php http://www.medicalnewstoday.com/articles/147400.php MR enterography is an effective tool to evaluate and guide treatment of patients with Crohn's Disease (a common form of inflammatory bowel disease that typically affects young people) without exposing them to radiation, according to a study performed at the Warren Alpert School of Medicine/Brown University in Providence, RI. "MR enterography is an MR examination targeted at the small bowel. Crohn's Wed, 01 Apr 2009 03:00:00 PDT http://www.medicalnewstoday.com/articles/144388.php http://www.medicalnewstoday.com/articles/144388.php Migration of colonic lamina propria fibroblasts (CLPF) plays an important role during the progression of fibrosis and fistulae in Crohn's disease. Transforming growth factor- beta (TGF- beta) is involved in the regulation of cell migration, cell differentiation, extracellular matrix deposition, and immune responses. Crohn's Mon, 30 Mar 2009 03:00:00 PDT http://www.medicalnewstoday.com/articles/144158.php http://www.medicalnewstoday.com/articles/144158.php Osiris Therapeutics, Inc. (NASDAQ: OSIR) announced that it has elected to end enrollment at 210 patients in its Phase III trial evaluating Prochymal for Crohn's disease. The Company believes there is a design flaw in the trial resulting in significantly higher than expected placebo response rates. The decision was made after the trial's final scheduled interim analysis showed that one of the two Prochymal dose arms had crossed a futility boundary. Crohn's Fri, 27 Feb 2009 01:00:00 PDT http://www.medicalnewstoday.com/articles/140473.php http://www.medicalnewstoday.com/articles/140473.php Discovering the different genes that contribute to a complex disease is like searching in the proverbial haystack for an unknown number of needles -- some much smaller than others, often blending into the background, and many of them widely separated from each other. But if some needles are linked to each other by fine threads, you might pull out clumps of them together. Crohn's Sat, 21 Feb 2009 00:00:00 PDT http://www.medicalnewstoday.com/articles/139774.php http://www.medicalnewstoday.com/articles/139774.php Cellular therapy with stem cells is revolutionizing the focus of treatment of many serious diseases. Replacing the cells of damaged tissue with other new cells from the same patient is already a reality. This is the basis of cellular therapy and regenerative medicine, the latest great advance in biomedicine. Crohn's Thu, 12 Feb 2009 00:00:00 PDT http://www.medicalnewstoday.com/articles/138667.php http://www.medicalnewstoday.com/articles/138667.php A team of scientists at The Scripps Research Institute has linked a mouse mutation to an increased susceptibility for developing inflammatory bowel disease -- represented in humans as Crohn's disease and ulcerative colitis, which together are estimated to affect more than a million people in the United States. The findings may one day lead to new and better treatments for the disease. Irritable-Bowel Syndrome Tue, 03 Feb 2009 08:00:00 PDT http://www.medicalnewstoday.com/articles/137700.php http://www.medicalnewstoday.com/articles/137700.php A tiny molecule found in most plant-based foods douses the flames before damaging lesions can form in the colon, according to a study by Texas AgriLife Research scientist Dr. Nancy Turner. Even better, the compound can be obtained easily by eating vegetables and fruit rather than by taking expensive prescriptions or supplements, Turner said. The molecule is quercetin. Colorectal Cancer Mon, 02 Feb 2009 00:00:00 PDT http://www.medicalnewstoday.com/articles/137418.php http://www.medicalnewstoday.com/articles/137418.php The administration of infliximab after intestinal resective surgery was found to be effective at preventing endoscopic and histological recurrence of Crohn's disease, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute. To date, there have been no randomized controlled trials evaluating infliximab for postoperative Crohn's disease prevention. Crohn's Tue, 27 Jan 2009 01:00:00 PDT http://www.medicalnewstoday.com/articles/136729.php http://www.medicalnewstoday.com/articles/136729.php Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that surveyed gastroenterologists say that a therapy's effect on maintenance of clinical remission is the attribute that most influences their choice in prescribing a maintenance therapy to prevent relapses of Crohn's disease. Crohn's