Copyright 2012 Medical News TodayLatest Health News and Medical News posted throughout the day, every day.http://www.medicalnewstoday.com/sections/cystic_fibrosis/admin@medicalnewstoday.com (MNT Admin)editors@medicalnewstoday.com (MNT Editors)en-us Tue, 31 Jan 2012 13:00:00 PSThttp://www.medicalnewstoday.com/articles/240990.phphttp://www.medicalnewstoday.com/articles/240990.php Kalydeco has been approved by the Food And Drug Administration (FDA) to treat a vicious type of Cystic Fibrosis (CF). CF is a deadly recessive disease which targets the lungs, but can also harm the liver, pancreas, and intestine. It occurs from the unusual transport of chloride and sodium across the epithelium, causing mucus buildup in the lungs, and thick secretions...Cystic Fibrosis Tue, 31 Jan 2012 00:00:00 PSThttp://www.medicalnewstoday.com/releases/240900.phphttp://www.medicalnewstoday.com/releases/240900.phpThe lung clearance index (LCI) is a sensitive non-invasive marker of early lung disease in young children with cystic fibrosis (CF), according to a new study from Australian researchers...Cystic Fibrosis Mon, 30 Jan 2012 09:00:00 PSThttp://www.medicalnewstoday.com/articles/240935.phphttp://www.medicalnewstoday.com/articles/240935.phpAccording to a new Australian study published online before he print publication in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine, the lung clearance index (LCI) is a sensitive, non-invasive marker of early lung disease in young children with cystic fibrosis (CF)...Cystic Fibrosis Mon, 23 Jan 2012 00:00:00 PSThttp://www.medicalnewstoday.com/releases/240576.phphttp://www.medicalnewstoday.com/releases/240576.phpA receptor found on blood platelets whose importance as a potential pharmaceutical target has long been questioned may in fact be fruitful in drug testing, according to new research from Michigan State University chemists. A team led by Dana Spence of MSU's Department of Chemistry has revealed a way to isolate and test the receptor known as P2X1...Blood / Hematology Wed, 18 Jan 2012 00:00:00 PSThttp://www.medicalnewstoday.com/releases/240371.phphttp://www.medicalnewstoday.com/releases/240371.phpWith one simple experiment, University of Illinois chemists have debunked a widely held misconception about an often-prescribed drug...Infectious Diseases / Bacteria / Viruses Tue, 20 Dec 2011 00:00:00 PSThttp://www.medicalnewstoday.com/releases/239407.phphttp://www.medicalnewstoday.com/releases/239407.phpAdding inhaled dry powder mannitol to standard therapy for cystic fibrosis produced sustained improvement in lung function for up to 52 weeks, according to a new study. Along with the treatment's efficacy and good safety profile, the convenience and ease of administration of mannitol treatment may improve adherence with therapy in these patients...Cystic Fibrosis Mon, 19 Dec 2011 10:00:00 PSThttp://www.medicalnewstoday.com/articles/239443.phphttp://www.medicalnewstoday.com/articles/239443.phpA new study found that the combination of inhaled dry powder mannitol with standard therapy for cystic fibrosis resulted in maintained improvement in lung function for 12 months. In addition to being effective and safe, the easy administration of the treatment might help enhance adherence with treatment in individuals suffering with the condition...Cystic Fibrosis Mon, 19 Dec 2011 01:00:00 PSThttp://www.medicalnewstoday.com/releases/239427.phphttp://www.medicalnewstoday.com/releases/239427.phpAdding inhaled dry powder mannitol to standard therapy for cystic fibrosis produced sustained improvement in lung function for up to 52 weeks, according to a new study. Along with the treatment's efficacy and good safety profile, the convenience and ease of administration of mannitol treatment may improve adherence with therapy in these patients...Cystic Fibrosis Tue, 13 Dec 2011 00:00:00 PSThttp://www.medicalnewstoday.com/releases/239004.phphttp://www.medicalnewstoday.com/releases/239004.phpSymptoms improved significantly in adults with the bleeding disorder hemophilia B following a single treatment with gene therapy developed by researchers at St. Jude Children's Research Hospital in Memphis and demonstrated to be safe in a clinical trial conducted at the University College London (UCL) in the U.K...Blood / Hematology Mon, 14 Nov 2011 01:00:00 PSThttp://www.medicalnewstoday.com/releases/237599.phphttp://www.medicalnewstoday.com/releases/237599.phpResearchers at Harvard Medical School and Children's Hospital Boston have retraced the evolution of an unusual bacterial infection as it spread among cystic fibrosis patients by sequencing scores of samples collected during the outbreak, since contained...Infectious Diseases / Bacteria / Viruses Fri, 04 Nov 2011 01:00:00 PSThttp://www.medicalnewstoday.com/releases/237061.phphttp://www.medicalnewstoday.com/releases/237061.phpResults of the pivotal Phase 3 clinical trial published in the Nov. 3, 2011 New England Journal of Medicine, find that the oral medication ivacaftor (VX-770) provides major, sustained improvement in lung function, growth and other signs and symptoms for cystic fibrosis (CF) patients...Cystic Fibrosis Fri, 04 Nov 2011 01:00:00 PSThttp://www.medicalnewstoday.com/releases/237083.phphttp://www.medicalnewstoday.com/releases/237083.phpA new study has confirmed that the drug, ivacaftor (VX-770), significantly improves lung function in some people with cystic fibrosis (CF). The results of the phase III clinical trial study, "A CFTR Potentiator in Patients with Cystic Fibrosis and the G551D Mutation," led by Bonnie W...Cystic Fibrosis Thu, 03 Nov 2011 01:00:00 PSThttp://www.medicalnewstoday.com/releases/236993.phphttp://www.medicalnewstoday.com/releases/236993.phpA new discovery by Californian scientists may lead to a pharmaceutical breakthrough for a wide range of illnesses that involve the hydration of cells that line the inner surfaces of our body's organs and tissues...Cystic Fibrosis Wed, 02 Nov 2011 01:00:00 PSThttp://www.medicalnewstoday.com/releases/236923.phphttp://www.medicalnewstoday.com/releases/236923.phpA vampire-like bacteria that leeches onto specific other bacteria - including certain human pathogens - has the potential to serve as a living antibiotic for a range of infectious diseases, a new study indicates...Infectious Diseases / Bacteria / Viruses Fri, 14 Oct 2011 00:00:00 PSThttp://www.medicalnewstoday.com/releases/235922.phphttp://www.medicalnewstoday.com/releases/235922.phpNew research in The FASEB Journal suggests that cigarette smoke interferes with the Cystic Fibrosis Transmembrane Conductance Regulator protein, leading to dry, sticky mucus and increased infections. If you smoke cigarettes, you have more in common with someone who has cystic fibrosis than you think...Cystic Fibrosis Wed, 21 Sep 2011 00:00:00 PSThttp://www.medicalnewstoday.com/releases/234691.phphttp://www.medicalnewstoday.com/releases/234691.phpCystic fibrosis (CF), a chronic disease that clogs the lungs and leads to life-threatening lung infections, is caused by a genetic defect in a chloride channel called cystic fibrosis transmembrane conductase regulator (CFTR)...Cystic Fibrosis Wed, 21 Sep 2011 00:00:00 PSThttp://www.medicalnewstoday.com/releases/234692.phphttp://www.medicalnewstoday.com/releases/234692.phpWhen researchers discovered the primary genetic defect that causes cystic fibrosis (CF) back in 1989, they opened up a new realm of research into treatment and a cure for the disease. Since then, scientists have been able to clone the defective gene and study its effects in animals...Cystic Fibrosis Tue, 06 Sep 2011 00:00:00 PSThttp://www.medicalnewstoday.com/releases/233811.phphttp://www.medicalnewstoday.com/releases/233811.php Researchers have identified an unconventional path that may correct the defect underlying cystic fibrosis, according to a report in the September 2nd issue of the journal Cell, a Cell Press publication. This new treatment dramatically extends the lives of mice carrying the disease-associated mutation...Cystic Fibrosis Thu, 25 Aug 2011 03:00:00 PSThttp://www.medicalnewstoday.com/articles/233326.phphttp://www.medicalnewstoday.com/articles/233326.phpA study published on bmj.com indicates, that even though improvements have been made in the last half century for the survival of cystic fibrosis sufferers, females and individuals from socio-economically disadvantaged backgrounds continue to die younger than males and those more privileged in society...Cystic Fibrosis Tue, 02 Aug 2011 03:00:00 PSThttp://www.medicalnewstoday.com/releases/232091.phphttp://www.medicalnewstoday.com/releases/232091.phpAzithromycin is an antibiotic that also has antiinflammatory properties. It is these antiinflammatory properties that are thought to account for the improvement in clinical outcome observed when patients with chronic lung diseases such as cystic fibrosis are treated long-term with azithromycin...Cystic Fibrosis Thu, 28 Jul 2011 00:00:00 PSThttp://www.medicalnewstoday.com/releases/231822.phphttp://www.medicalnewstoday.com/releases/231822.phpCase Western Reserve University School of Medicine has received a $2.1 million grant from the National Center for Research Resources, part of the National Institutes of Health (NIH), to expand basic research models for the study of cystic fibrosis (CF). CF is an inherited disease that causes thick, sticky mucus to build up in the lungs and digestive tract...Cystic Fibrosis Thu, 21 Jul 2011 01:00:00 PSThttp://www.medicalnewstoday.com/releases/231468.phphttp://www.medicalnewstoday.com/releases/231468.phpMicrobiologists have uncovered a sneaky trick by the bacterium Pseudomonas aeruginosa to oust rivals. It deploys a toxin delivery machine to breach cell walls of competitors without hurting itself. Its means of attack helps it survive in the outside environment and may even help it cause infection. P...Infectious Diseases / Bacteria / Viruses Tue, 19 Jul 2011 04:00:00 PSThttp://www.medicalnewstoday.com/releases/231334.phphttp://www.medicalnewstoday.com/releases/231334.phpBacteria use various appendages to move across surfaces prior to forming multicellular bacterial biofilms. Some species display a particularly jerky form of movement known as "twitching" motility, which is made possible by hairlike structures on their surface called type IV pili, or TFP...Infectious Diseases / Bacteria / Viruses Tue, 19 Jul 2011 02:00:00 PSThttp://www.medicalnewstoday.com/releases/231323.phphttp://www.medicalnewstoday.com/releases/231323.phpONCOLOGY: Platinum-based drugs: double trouble for tumors One of the reasons that tumors are able to grow rapidly is that they actively prevent immune cells from generating effective antitumor immune responses. Researchers are developing approaches to combat the mechanisms used by tumors to inhibit immune responses, but such approaches don't kill tumor cells directly...Cancer / Oncology Fri, 15 Jul 2011 04:00:00 PSThttp://www.medicalnewstoday.com/articles/231169.phphttp://www.medicalnewstoday.com/articles/231169.php A comparative study published in July 13 issue of JAMA noticed, treatment based on a new invasive diagnostic procedure for treating cystic fibrosis in infants that involves obtaining and culturing fluid samples from the lungs, when compared with standard diagnostic procedure, did not have a lower prevalence of lung-damaging infection or structural lung injury at 5 years of age...Cystic Fibrosis