Copyright 2009 Medical News Today Latest Endocrinology News From Medical News Today. http://www.medicalnewstoday.com/sections/endocrinology/ admin@medicalnewstoday.com (MNT Admin) editors@medicalnewstoday.com (MNT Editors) en-us Fri, 03 Jul 2009 01:00:00 PDT http://www.medicalnewstoday.com/articles/156239.php http://www.medicalnewstoday.com/articles/156239.php The single-nucleotide polymorphism (SNP) known as 2q35-rs13387042 is associated with increased risk of estrogen receptor (ER) -positive and -negative breast cancer, according to a study published online July 1 in the Journal of the National Cancer Institute. This study was undertaken to confirm previous research that identified this SNP as a marker of susceptibility to ER-positive breast cancer. Roger L. Milne, Ph.D. Breast Cancer Fri, 03 Jul 2009 01:00:00 PDT http://www.medicalnewstoday.com/articles/156248.php http://www.medicalnewstoday.com/articles/156248.php Scientists in the UK and Denmark have shown that if elderly men were given growth hormone and exercised their legs showed an appreciable muscle mass increase. Dr. Geoff Goldspink (Royal Free and University College Medical School, UK) says: "This raises the question: Can age-related loss of muscle strength and increased fragility be ameliorated by the therapeutic application of mechano growth factor (MGF)?". Seniors / Aging Fri, 03 Jul 2009 00:00:00 PDT http://www.medicalnewstoday.com/articles/156220.php http://www.medicalnewstoday.com/articles/156220.php New research at Rhode Island Hospital has uncovered the biological effects of a novel membrane estrogen receptor, a finding that has potential implications for hormonal therapy for breast cancer. The study is published in the July edition of the journal Molecular Endocrinology. Breast Cancer Thu, 02 Jul 2009 05:00:00 PDT http://www.medicalnewstoday.com/articles/156182.php http://www.medicalnewstoday.com/articles/156182.php A scary unknown for many children, the prospect of surgery can cause intense preoperative anxiety. While some amount of stress is normal, what many parents do not know is that extreme anxiety before surgery can contribute to the occurrence of emergence delirium, a distressing incidence of acute behavioral changes experienced when "waking up" from anesthesia. Pediatrics / Children's Health Thu, 02 Jul 2009 00:00:00 PDT http://www.medicalnewstoday.com/articles/156046.php http://www.medicalnewstoday.com/articles/156046.php Researchers at the Sahlgrenska Academy, Gothenburg, have discovered a new brain mechanism involved in alcohol addiction involving the stomach hormone ghrelin. When ghrelin's actions in the brain are blocked, alcohol's effects on the reward system are reduced. It is an important discovery that could lead to new therapies for addictions such as alcohol dependence. Alcohol / Addiction / Illegal Drugs Wed, 01 Jul 2009 03:00:00 PDT http://www.medicalnewstoday.com/articles/155955.php http://www.medicalnewstoday.com/articles/155955.php BioSante Pharmaceuticals, Inc. (NASDAQ: BPAX), which is developing a testosterone gel (LibiGel®) to treat hypoactive sexual desire disorder (HSDD) in women, is pleased to comment on results in a paper published in the July issue of The Journal of Sexual Medicine showing testosterone has no effect on the incidence of invasive breast cancer among menopausal women who use testosterone to improve sexual function. The study, led by Susan Davis, M.D. Sexual Health / STDs Wed, 01 Jul 2009 02:00:00 PDT http://www.medicalnewstoday.com/articles/155918.php http://www.medicalnewstoday.com/articles/155918.php Upsher-Smith Laboratories, Inc. presented the results of a secondary analysis to determine the response rates to three doses of transdermal Divigel(R) (estradiol gel) 0.1 percent at the recent 57th Annual Clinical Meeting of the American College of Obstetricians and Gynecologists (ACOG) in Chicago. Endocrinology Wed, 01 Jul 2009 02:00:00 PDT http://www.medicalnewstoday.com/articles/155928.php http://www.medicalnewstoday.com/articles/155928.php Physiological changes associated with the metabolic syndrome may play a role in the risk of postmenopausal breast cancer, according to study results published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research. Breast Cancer Wed, 01 Jul 2009 01:00:00 PDT http://www.medicalnewstoday.com/articles/155916.php http://www.medicalnewstoday.com/articles/155916.php PROLOR Biotech, Inc. (OTC Bulletin Board: PBTH), formerly Modigene Inc., announced that the U. S. Patent and Trademark Office (PTO) has issued two new patents for the company's long-acting CTP-enhanced human growth hormone (hGH-CTP) and human erythropoietin (EPO-CTP). The patents cover the composition of PROLOR's proprietary pharmaceutical compounds as well as certain associated methods. Endocrinology Wed, 01 Jul 2009 00:00:00 PDT http://www.medicalnewstoday.com/articles/155892.php http://www.medicalnewstoday.com/articles/155892.php In a study with important consequences for studies on the effects of chemicals on steroid responses in humans, a team of French and American scientists, including Michael E. Baker, PhD, professor in UC San Diego's Department of Medicine, Division of Nephrology-Hypertension, have found that - contrary to earlier assumptions - enzymes used for the synthesis of steroids in insects, snails, octopuses and corals are unrelated to those used in humans. Endocrinology Tue, 30 Jun 2009 06:00:00 PDT http://www.medicalnewstoday.com/articles/155858.php http://www.medicalnewstoday.com/articles/155858.php Interest and concern about possible health threats posed by endocrine-disrupting chemicals (EDCs) is on the rise, yet there is currently no comprehensive coordinated approach to regulating EDCs in the United States. To address this emerging public health issue, The Endocrine Society today released a new position statement outlining the public health concerns of exposure to EDCs and proposing a series of recommendations for revising current policy and generating new policy on EDCs. Endocrinology Tue, 30 Jun 2009 02:00:00 PDT http://www.medicalnewstoday.com/articles/155752.php http://www.medicalnewstoday.com/articles/155752.php UT Southwestern Medical Center researchers are conducting two pilot clinical trials to determine whether a single, early dose of estrogen can improve survival and neurological outcomes after severe traumatic brain injury or traumatic hemorrhagic shock. Neurology / Neuroscience Tue, 30 Jun 2009 01:00:00 PDT http://www.medicalnewstoday.com/articles/155746.php http://www.medicalnewstoday.com/articles/155746.php On June 26, 2009 several articles published online in Diabetologia by the European Association for the Study of Diabetes investigated the possible relationship between use of insulin glargine (Lantus, sanofi-aventis) and the development of certain malignancies. The authors themselves, and the accompanying editorial, cautioned against over-interpretation of their limited data and analyses, which precluded them from drawing any firm conclusions. Cancer / Oncology Sun, 28 Jun 2009 00:00:00 PDT http://www.medicalnewstoday.com/articles/155542.php http://www.medicalnewstoday.com/articles/155542.php The recent decline in invasive breast cancer in the US was significantly less pronounced in the poor and those who live in rural areas. Researchers writing in the open access journal BMC Medicine suggest this may be due to varying reductions in the numbers of women taking hormone therapy (HT). Christina Clarke, Ph.D. Breast Cancer Fri, 26 Jun 2009 01:00:00 PDT http://www.medicalnewstoday.com/articles/155390.php http://www.medicalnewstoday.com/articles/155390.php Experiment after experiment confirms that a diet on the brink of starvation expands lifespan in mice and many other species. But the molecular mechanism that links nutrition and survival is still poorly understood. Now, researchers at the Salk Institute for Biological Studies have identified a pivotal role for two enzymes that work together to determine the health benefits of diet restriction. Nutrition / Diet Thu, 25 Jun 2009 00:00:00 PDT http://www.medicalnewstoday.com/articles/155204.php http://www.medicalnewstoday.com/articles/155204.php A lack of serotonin, commonly known as the "happiness hormone", in the brain slows the growth of mice after birth and is responsible for impaired maternal behavior later in life. This was the result of research conducted by Dr. Natalia Alenina, Dana Kikic, and Professor Michael Bader of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch, Germany. Endocrinology Wed, 24 Jun 2009 02:00:00 PDT http://www.medicalnewstoday.com/articles/155079.php http://www.medicalnewstoday.com/articles/155079.php Melatonin can slow down the effects of aging. A team at laboratoire Arago in Banyuls sur Mer (CNRS / Université Pierre et Marie Curie) has found that a treatment based on melatonin can delay the first signs of aging in a small mammal. These results appeared in the journal PLoS ONE on 15 June 2009. Better known as the 'time-keeping' hormone, melatonin is naturally secreted by the body during the night. Seniors / Aging Tue, 23 Jun 2009 01:00:00 PDT http://www.medicalnewstoday.com/articles/154891.php http://www.medicalnewstoday.com/articles/154891.php Amicus Therapeutics (Nasdaq: FOLD) announced it has commenced the U.S. registration Phase 3 trial with its investigational drug, Amigal(TM) (migalastat hydrochloride) for the treatment of Fabry disease. The Company has reached agreement with the U.S. Endocrinology Sat, 20 Jun 2009 00:00:00 PDT http://www.medicalnewstoday.com/articles/154699.php http://www.medicalnewstoday.com/articles/154699.php A period, or menstruation, is the shedding of the endometrium - the uterine lining. Menstruation is also known as menses. All female humans, as well as some other female mammals, have regular periods during their reproductive age. Menstruation which includes bleeding from the vagina is found mainly among humans and similar animals, such as primates. In many mammals, the endometrium is reabsorbed by the animal. Women's Health / Gynecology Thu, 18 Jun 2009 06:00:00 PDT http://www.medicalnewstoday.com/articles/154462.php http://www.medicalnewstoday.com/articles/154462.php Endocrine Society Unveils First-Ever Scientific Statement: Inaugural Statement Identifies Endocrine-Disrupting Chemicals as a Significant Concern to Public Health The Endocrine Society presented its first-ever Scientific Statement on endocrine-disrupting chemicals today at ENDO 09, the 91st Annual Meeting of The Endocrine Society. Endocrinology Thu, 18 Jun 2009 06:00:00 PDT http://www.medicalnewstoday.com/articles/154463.php http://www.medicalnewstoday.com/articles/154463.php Today, The Endocrine Society announced Newsweek Reporters Barbara Kantrowitz and Patrice Wingert recipients of the Society's second annual Award for Excellence in Science and Medical Journalism. The co-authors of the winning article, "Uh, O!" (O for Oprah) were honored last night at the Society's 91st Annual Meeting in Washington, DC. Endocrinology Thu, 18 Jun 2009 06:00:00 PDT http://www.medicalnewstoday.com/articles/154464.php http://www.medicalnewstoday.com/articles/154464.php The Endocrine Society's Corporate Liaison Board (CLB) will host its annual forum on Wednesday June 10, as part of ENDO 09, the Society's 91th Annual Meeting. The 2009 topic for the forum is "Biomarkers in Cardiovascular Endocrinology in Clinical Trials & Drug Development. Endocrinology Thu, 18 Jun 2009 06:00:00 PDT http://www.medicalnewstoday.com/articles/154465.php http://www.medicalnewstoday.com/articles/154465.php The Endocrine Society is pleased to announce the 2009 Laureate Awards established in 1944 to recognize the highest achievements in endocrinology including: science, leadership, teaching and service. This year's Laureate Awards were presented at ENDO 09, the 91st Annual Meeting of The Endocrine Society, being held June 10-13, in Washington, DC. The Endocrine Society's 2009 Laureate Award winners are: - Daniel Drucker, MD - Clinical Investigator Award Lecture. Endocrinology Wed, 17 Jun 2009 03:00:00 PDT http://www.medicalnewstoday.com/articles/154196.php http://www.medicalnewstoday.com/articles/154196.php New data presented showed that pitavastatin is an effective treatment for the management of dyslipidemia in elderly patients, with a similar safety and tolerability profile to low-dose pravastatin. The Phase III data were presented by Kowa, at the XV International Symposium on Atherosclerosis in Boston. Endocrinology Wed, 17 Jun 2009 01:00:00 PDT http://www.medicalnewstoday.com/articles/154148.php http://www.medicalnewstoday.com/articles/154148.php Neurological diseases including Parkinson's, Tourette's, attention deficit hyperactivity disorder (ADHD), Alzheimer's, and schizophrenia are all associated with alterations in dopamine-driven function involving the dopamine transporter (DAT). Research published recently in the open access journal BMC Neuroscience suggests that a number of estrogens acting through their receptors affect the DAT, which may explain trends in timing of women's susceptibility to these diseases. Neurology / Neuroscience