Copyright 2008 Medical News Today Latest Gout News From Medical News Today. http://www.medicalnewstoday.com/sections/gout/ admin@medicalnewstoday.com (MNT Admin) editors@medicalnewstoday.com (MNT Editors) en-us Tue, 06 May 2008 02:00:00 PDT http://www.medicalnewstoday.com/articles/106338.php Ipsen (Paris:IPN) announced that the European Commission granted marketing authorisation for Adenuric® (febuxostat) for the treatment of chronic hyperuricaemia in gout. Adenuric® thus pioneers the first major treatment alternative for gout, a severe debilitating disease, for more than 40 years. Mon, 10 Mar 2008 07:00:00 PDT http://www.medicalnewstoday.com/articles/100073.php A study led by a team of scientists in Scotland suggests that genes may play a part in increasing one's risk of developing gout, a painful condition that affects the joints.The study is published in the 9 March online issue of Nature Genetics and is the work of researchers based at the MRC Human Genetics Unit, Western General Hospital, Edinburgh, and colleagues from other research centres in the UK and also in Croatia and Germany. Mon, 03 Mar 2008 04:00:00 PDT http://www.medicalnewstoday.com/articles/99221.php Savient Pharmaceuticals, Inc. (NASDAQ: SVNT) announced further information related to infusion reactions and deaths for their Phase 3 clinical trials for Puricase(R) (pegloticase) being developed for treatment failure gout patients. Severe and Serious Infusion Reactions Our preliminary analysis indicated that 19 patients or 11% of pegloticase treated patients experienced an infusion reaction termed "serious" or "severe. Mon, 25 Feb 2008 03:00:00 PDT http://www.medicalnewstoday.com/articles/98426.php Ipsen (Paris:IPN) announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMEA) provided a positive opinion for Adenuric® (febuxostat) 80 mg and 120 mg tablets for the treatment of chronic hyperuricaemia in gout and recommended it for marketing authorisation. The CHMP recommendation will now be forwarded to the European Commission for final marketing approval, which typically occurs within 60 to 90 days. Wed, 06 Feb 2008 02:00:00 PDT http://www.medicalnewstoday.com/articles/96322.php Savient Pharmaceuticals, Inc. (NASDAQ:SVNT), announced additional positive results for secondary efficacy endpoints in the two replicate Phase 3 studies for Puricase(R)(pegloticase) for treatment-failure gout. Tue, 05 Feb 2008 00:00:00 PDT http://www.medicalnewstoday.com/articles/96164.php According to a recent study published on bmj.com,men who drink sugary soft drinks and eat fructose have an increasedrisk of gout.Gout is a disease caused by a buildup of uric acid in the blood(hyperuricemia) that provokes an inflammatory reaction in tissues andjoints. It is often painful and is most common in men 40 years of ageand older. Over the last few decades, levels of gout in the UnitedStates have doubled. Mon, 04 Feb 2008 04:00:00 PDT http://www.medicalnewstoday.com/articles/96073.php "Soft drinks 'bigger gout risk than alcohol'" read the headline in The Daily Telegraph today. It reported that "drinking too many sugary soft drinks and fruit juices can substantially increase the risk of gout". Gout can be extremely painful and is caused by a build up of uric acid that crystallises in the joints. Uric acid is formed by the breakdown of purines which occur naturally in the body as well as in the diet. Thu, 03 Jan 2008 03:00:00 PDT http://www.medicalnewstoday.com/articles/92947.php Arthritis is the most common cause of disability in the United States. Over the next 25 years as the Baby Boom generation continues to age, the toll of this disease will escalate. To have a clear picture of the looming disease burden and its impact on our nation's health care and public health systems, estimating disease prevalence - the number of people affected by any form of arthritis - is critical. Fri, 19 Oct 2007 03:00:00 PDT http://www.medicalnewstoday.com/articles/85968.php Savient Pharmaceuticals, Inc. (NASDAQ: SVNT) announced the completion of the in-life portion of its two pivotal Phase 3 clinical trials for Puricase® (pegloticase) in patients with treatment-failure gout, an orphan indication. Puricase is a pegylated recombinant mammalian urate oxidase that is being developed to control hyperuricemia and its clinical consequences in patients for whom conventional therapy is contraindicated or has been ineffective. Sat, 02 Jun 2007 08:00:00 PDT http://www.medicalnewstoday.com/articles/72360.php High uric acid levels in the blood are a precursor of gout, the most common inflammatory arthritis in adult men. It is believed that coffee and tea consumption may affect uric acid levels but only one study has been conducted to date. A new large-scale study published in the June 2007 issue of Arthritis Care & Research (http://www.interscience.wiley. Tue, 29 May 2007 17:00:00 PDT http://www.medicalnewstoday.com/articles/72324.php Coffee is a habit for more than 50 percent of Americans, who drink, on average, 2 cups per day. This widely consumed beverage is regularly investigated and debated for its impact on health conditions from breast cancer to heart disease. Among its complex effects on the body, coffee or its components have been linked to lower insulin and uric acid levels on a short-term basis or cross-sectionally. Tue, 13 Mar 2007 00:00:00 PDT http://www.medicalnewstoday.com/articles/65095.php Savient Pharmaceuticals, Inc. (NASDAQ:SVNT) announced today that it has reached its Phase 3 enrollment target of 200 patients total, in the two replicate placebo-controlled six-month clinical trials. The trials assess the safety and efficacy of Puricase in patients with treatment-failure gout, under the auspices of a Special Protocol Assessment from the U.S. Food and Drug Administration. Mon, 13 Nov 2006 00:00:00 PDT http://www.medicalnewstoday.com/articles/56501.php Climatic factors such as heat and humidity that lead to dehydration can signal a future attack for gout sufferers, according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in Washington DC.Gout, caused by deposits of monosodium uric crystals, causes severe pain and swelling of the joints. Sat, 11 Nov 2006 04:00:00 PDT http://www.medicalnewstoday.com/articles/56375.php Results of a new survey show that two-thirds (65 percent) of gout patients ranked their typical gout flares -- defined as a sudden, intense pain -- as either close to, or the worst pain possible and say that the flares last an average of eight days. Seventy-two percent reported having experienced at least one flare within the last 12 months. The online survey of 321 gout patients was conducted by Harris Interactive(R) on behalf of Savient Pharmaceuticals, Inc. Fri, 10 Nov 2006 00:00:00 PDT http://www.medicalnewstoday.com/articles/56338.php The Gout & Uric Acid Education Society, a non-profit group of health care professionals, today launched http://www.gouteducation.org , a valuable educational resource for gout sufferers and their caregivers. The Web site is designed to help gout sufferers enhance their understanding of the disease and its treatments, embrace lifestyle modifications and, ideally, restore some control and spontaneity to their lives. Mon, 07 Aug 2006 01:00:00 PDT http://www.medicalnewstoday.com/articles/48726.php People with gout are at increased risk of having a heart attack, according to a University of Pittsburgh School of Medicine study published in the August edition of the journal Arthritis & Rheumatism. The article is available on line at http://www3.interscience.wiley.com/cgi-bin/jhome/76509746. Sat, 05 Aug 2006 23:00:00 PDT http://www.medicalnewstoday.com/articles/48625.php For over 100 years we have known that the intensely painful disease gout is caused by the accumulation of monosodium urate crystals (MSU) in joints. Now, in a study appearing in the August issue of the Journal of Clinical Investigation, Kenneth Rock and colleagues from University of Massachusetts Medical School uncover how these crystal deposits are recognized by the immune system and trigger acute and painful inflammation. Mon, 17 Jul 2006 00:00:00 PDT http://www.medicalnewstoday.com/articles/47230.php The first new class of drug to emerge in 40 years for treating chronic gout has the potential to radically alter the outlook for thousands of patients unable to benefit from currently available therapies, says the drug's developer Savient Pharmaceuticals Inc. who presented Phase II data at this year's annual meeting of the European rheumatology community, EULAR. Mon, 28 Nov 2005 17:00:00 PDT http://www.medicalnewstoday.com/articles/34203.php Savient Pharmaceuticals, Inc announced that patients withelevated blood uric acid levels and treatment-resistant gout who were treatedwith its investigational drug Puricase(R) (PEG-uricase) had substantial andsustained reduction in plasma urate levels, according to study results thatwere presented on Wednesday, November 16 at the American College ofRheumatology 2005 Annual Meeting. Wed, 12 Jan 2005 10:00:00 PDT http://www.medicalnewstoday.com/articles/18815.php Savient Pharmaceuticals, Inc (NASDAQ: SVNT), an emerging specialty pharmaceutical company engaged in developing, manufacturing and marketing pharmaceutical products that address unmet medical needs today announced the completion of patient dosing in a Phase 2 clinical trial of Puricase(R), a poly(ethylene glycol) ("PEG") conjugate of recombinant porcine uricase (urate oxidase), for the treatment of severe, refractory gout. Fri, 17 Dec 2004 10:00:00 PDT http://www.medicalnewstoday.com/articles/17987.php OSAKA, JAPAN --- Takeda Pharmaceutical Company Limited ("Takeda") announced today that TAP Pharmaceutical Products Inc ("TAP"), its 50-50 joint venture with Abbott Laboratories, submitted a New Drug Application ("NDA") on December 14 with the US Food and Drug Administration for febuxostat 80mg and 120mg for the management of hyperuricemia in patients with chronic gout. Wed, 10 Mar 2004 00:00:00 PDT http://www.medicalnewstoday.com/articles/6461.php If you want to prevent painful gout you should drink milk and dairy products. You should not, however, eat lots of red meat and seafood. This is according to a report in the New England Journal of Medicine. Dr. Hyon Choi, study leader, said that this is the first evidence that dairy products can be strongly protective against gout. Dr. Choi works at the Massachusetts General Hospital.