Copyright 2010 Medical News TodayLatest Health News and Medical News posted throughout the day, every day.http://www.medicalnewstoday.com/sections/lupus/admin@medicalnewstoday.com (MNT Admin)editors@medicalnewstoday.com (MNT Editors)en-us Tue, 26 Jan 2010 05:00:00 PSThttp://mnt.to/f/3wNphttp://mnt.to/f/3wNpThe links between autoimmune diseases, infections, genetics and the environment are complex and mysterious...Arthritis / Rheumatology Tue, 26 Jan 2010 01:00:00 PSThttp://mnt.to/f/3wLthttp://mnt.to/f/3wLtInvestigators have identified a new disease mechanism and therapeutic approach for a type of advanced kidney disease that is a common cause of complications in patients with lupus. The study was led by investigators at Hospital for Special Surgery and appears in the January 25 online Early Edition of the Proceedings of the National Academy of Sciences...Urology / Nephrology Wed, 13 Jan 2010 12:00:00 PSThttp://mnt.to/f/3wg9http://mnt.to/f/3wg9The Lupus Foundation of America, Inc. (LFA) is seeking applications for its 2010 Gina M. Finzi Memorial Student Summer Fellowship Program. The purpose of these awards is to foster an interest among young investigators in lupus research under the supervision of an established in investigator...Lupus Tue, 12 Jan 2010 03:00:00 PSThttp://mnt.to/f/3wbBhttp://mnt.to/f/3wbBA U.S. patent has been issued to Immunomedics, Inc. for epratuzumab, a monoclonal antibody under development as a potential new treatment for lupus. In August of 2009, Immunomedics and its partner, UCB of Belgium, reported promising data from a phase IIb clinical study of epratuzumab involving 227 individuals with moderate to severe lupus. Learn more about these results...Lupus Mon, 28 Dec 2009 00:00:00 PSThttp://mnt.to/f/3vKkhttp://mnt.to/f/3vKkIdentical twins look the same and are nearly genetically identical, but environmental factors and the resulting cellular changes could cause disease in one sibling and not the other. In a study published online in Genome Research (www.genome...Lupus Wed, 02 Dec 2009 00:00:00 PSThttp://mnt.to/f/3tTYhttp://mnt.to/f/3tTYJulian Lennon, son of the legendary John Lennon, and James Scott Cook announced today that they will donate a portion of the proceeds from their song, "LUCY," to fund research on the disease lupus...Lupus Thu, 26 Nov 2009 01:00:00 PSThttp://mnt.to/f/3tJLhttp://mnt.to/f/3tJLThe Lupus Research Institute (LRI) has named 12 new grant recipients for 2009. The awards, totaling $3.6 million, recognize innovative work across a broad spectrum of lupus research. All were selected for their creativity, novelty, and potential to drive scientific discovery to ultimately prevent, treat, and cure the complex disease of systemic lupus...Lupus Mon, 23 Nov 2009 03:00:00 PSThttp://mnt.to/f/3tBdhttp://mnt.to/f/3tBdImmuPharma PLC announced the final results from a Phase IIb trial of LUPUZOR™ in active patients with Systemic Lupus Erythematosus (SLE). Lupuzor™ administered at 200 mcg once-a-month for 3 months plus standard of care achieved a clinically significant improvement in patient response rate as measured by the combined score compared to placebo plus standard of care...Lupus Fri, 20 Nov 2009 00:00:00 PSThttp://mnt.to/f/3tsZhttp://mnt.to/f/3tsZIn a step toward using human saliva to tell whether those stiff joints, memory lapses, and other telltale signs of aging are normal or red flags for disease, scientists are describing how the protein content of women's saliva change with advancing age...Women's Health / Gynecology Thu, 19 Nov 2009 18:00:00 PSThttp://mnt.to/f/3tt4http://mnt.to/f/3tt4ImmuPharma PLC (LSE:IMM) the specialist discovery and development pharmaceutical company is pleased to announce the final results from a Phase IIb trial of LUPUZOR™ in active patients with Systemic Lupus Erythematosus (SLE)...Lupus Wed, 04 Nov 2009 00:00:00 PSThttp://mnt.to/f/3sHchttp://mnt.to/f/3sHcAs if there weren't enough reasons to stop smoking, a team of researchers at the Research Institute of the McGill University Health Centre (RI-MUHC) have just found another. A study led by Dr. Christian A Pineau, Co-Director of the Lupus and Vasculitis clinic at the MUHC, has clearly linked skin damage and rashes to smoking in people with systemic lupus erythematosus (SLE)...Lupus Tue, 03 Nov 2009 07:00:00 PSThttp://mnt.to/f/3sG3http://mnt.to/f/3sG3Human Genome Sciences (HGS) and GlaxoSmithKline (GSK) today announced positive results from BLISS-76, the second of two large-scale phase III clinical trials of BENLYSTA™ (belimumab) for treating systemic lupus. A full presentation of results from BLISS-52 was recently shared at the 73rd Annual Scientific meeting of the American College of Rheumatology...Lupus Tue, 03 Nov 2009 02:00:00 PSThttp://mnt.to/f/3sDBhttp://mnt.to/f/3sDBThe Lupus Research Institute (LRI) and its National Coalition of state and local lupus organizations congratulate Human Genome Sciences (HGS) and GlaxoSmithKline for achieving an historical landmark - the second positive phase 3 clinical trial of Benlysta (belimumab), the first successfully tested new drug developed specifically for people with systemic lupus...Lupus Tue, 03 Nov 2009 00:00:00 PSThttp://mnt.to/f/3sCChttp://mnt.to/f/3sCCHuman Genome Sciences (HGS) and GlaxoSmithKline (GSK) announced positive results from BLISS-76, the second of two large-scale phase III clinical trials of BENLYSTA™ (belimumab) for treating systemic lupus. A full presentation of results from BLISS-52 was recently shared at the 73rd Annual Scientific meeting of the American College of Rheumatology...Lupus Mon, 02 Nov 2009 03:00:00 PSThttp://mnt.to/f/3sBChttp://mnt.to/f/3sBCIndividuals with a history of lupus who receive a kidney transplant rarely develop the serious inflammatory condition lupus nephritis in their new organ, according to a paper being presented at the American Society of Nephrology's 42nd Annual Meeting and Scientific Exposition in San Diego, CA...Transplants / Organ Donations Mon, 19 Oct 2009 04:00:00 PSThttp://mnt.to/f/3rVshttp://mnt.to/f/3rVsMacrophages, the scavenger cells of the body's immune system, are responsible for disposing of dying cells. Stanford University School of Medicine researchers have identified one pathway in this important process in mice that, if disrupted, causes a lupuslike autoimmune disease...Lupus Mon, 19 Oct 2009 01:00:00 PSThttp://mnt.to/f/3rT7http://mnt.to/f/3rT7According to a new study by Hospital for Special Surgery investigators presented at the American College of Rheumatology meeting on October 21 in Philadelphia, most lupus patients are not aware that their condition puts them at a higher risk for cardiovascular disease and a counseling program is a valuable way to promote education and lifestyle change...Lupus Wed, 07 Oct 2009 00:00:00 PSThttp://mnt.to/f/3rjShttp://mnt.to/f/3rjSThe Lewin Group, a national health care consulting firm, has issued recommendations on ways to overcome the barriers that have obstructed lupus drug development resulting in no new drug approval for this disease in more than 50 years - since the Eisenhower Administration...Lupus Tue, 06 Oct 2009 09:00:00 PSThttp://mnt.to/f/3rhLhttp://mnt.to/f/3rhLThe Lewin Group, a national health care consulting firm, issued recommendations on ways to overcome the barriers that have obstructed lupus drug development resulting in no new drug approval for this disease in more than 50 years- since the Eisenhower Administration...Lupus Mon, 28 Sep 2009 00:00:00 PSThttp://mnt.to/f/3qS6http://mnt.to/f/3qS6An article published Online First and in the November edition of The Lancet Neurology reports that women with a particular subtype of antibody called lupus anticoagulant (LA) have a more than 40-fold increased risk of stroke. Moreover, they have a 5-fold increased risk of heart attack compared with the general population of young women...Neurology / Neuroscience Wed, 23 Sep 2009 01:00:00 PSThttp://mnt.to/f/3qFRhttp://mnt.to/f/3qFR It's been 50 years since the U.S. Food and Drug Administration (FDA) approved a medication to treat lupus -- when Dwight D. Eisenhower was President! To highlight the need for safer, more tolerable, and effective medications, the Lupus Foundation of America, Inc...Lupus Wed, 09 Sep 2009 02:00:00 PSThttp://mnt.to/f/3q2Nhttp://mnt.to/f/3q2NIn patients with systemic lupus erythematosus, their race can affect how severe the disease will become, according to a new study. Systemic lupus erythematosus (SLE) is the most common form of lupus a chronic inflammatory disease that can affect various parts of the body, especially the kidneys, joints, blood and nervous system...Lupus Mon, 07 Sep 2009 03:00:00 PSThttp://mnt.to/f/3pXBhttp://mnt.to/f/3pXBHuman Genome Sciences, Inc. (NASDAQ:HGSI) announced publication by the journal of an article describing the development and use of a novel evidence-based systemic lupus erythematosus (SLE) Responder Index selected as the primary endpoint of two pivotal Phase 3 clinical trials of BENLYSTA™ (belimumab) in serologically active patients with SLE...Lupus Wed, 02 Sep 2009 23:00:00 PSThttp://mnt.to/f/3pMDhttp://mnt.to/f/3pMDIt has been more than 50 years since the U.S. Food and Drug Administration (FDA) last approved a new medicine specifically for lupus - when Dwight D. Eisenhower was president. Existing treatments have been "borrowed" from other disorders and the risk/benefit ratio of these treatments is far from optimal. However, hope is on the horizon...Lupus Fri, 28 Aug 2009 00:00:00 PSThttp://mnt.to/f/3pwHhttp://mnt.to/f/3pwHUCB and Immunomedics (NASDAQ: IMMU) announced top-line results from UCB's Phase IIb clinical study comparing epratuzumab to placebo in patients with systemic lupus erythematosus (SLE, also commonly known as lupus). The data from the 12-week dose and regimen-ranging study demonstrated clinical meaningful treatment effect of epratuzumab over placebo in SLE patients...Lupus