Copyright 2010 Medical News TodayLatest Health News and Medical News posted throughout the day, every day.http://www.medicalnewstoday.com/sections/lymphoma-leukemia/admin@medicalnewstoday.com (MNT Admin)editors@medicalnewstoday.com (MNT Editors)en-us Sat, 31 Jul 2010 00:00:00 PDThttp://mnt.to/f/3GNzhttp://mnt.to/f/3GNzThe Food and Drug Administration (FDA) received reports of malignancies in children using tumor necrosis factor a (TNF) blockers, raising concerns of an associated risk and prompting an investigation...Arthritis / Rheumatology Fri, 30 Jul 2010 03:00:00 PDThttp://mnt.to/f/3GMFhttp://mnt.to/f/3GMFThe National Institute for Health and Clinical Excellence (NICE) extended its recommendation for the use of targeted antibody MabThera® (rituximab) to include people with relapsed and difficult-to-treat (refractory) chronic lymphocytic leukaemia (CLL) except where patients have received the full therapeutic dose of MabThera in the first line setting or are refractory to fludarabine...Lymphoma / Leukemia / Myeloma Thu, 29 Jul 2010 02:00:00 PDThttp://mnt.to/f/3GJwhttp://mnt.to/f/3GJwThe prognosis for nearly three-quarters of elderly patients on intensive chemotherapy for acute myeloid leukemia (AML) is poor, with a median survival of less than six months, according to a study published online in Blood, the journal of the American Society of Hematology...Lymphoma / Leukemia / Myeloma Thu, 29 Jul 2010 02:00:00 PDThttp://mnt.to/f/3GJChttp://mnt.to/f/3GJCScientists in Japan may have developed a way to accurately predict those patients who will resist treatment with imatinib, which is the standard of care for chronic myeloid leukemia (CML). Results are published in Clinical Cancer Research, a journal of the American Association for Cancer Research...Lymphoma / Leukemia / Myeloma Thu, 29 Jul 2010 00:00:00 PDThttp://mnt.to/f/3GHchttp://mnt.to/f/3GHcTransforming Growth Factor-βa (TGF-β1) Contributes to Kidney Disease Dr...Urology / Nephrology Thu, 29 Jul 2010 00:00:00 PDThttp://mnt.to/f/3GHFhttp://mnt.to/f/3GHFSynta Pharmaceuticals Corp...Lymphoma / Leukemia / Myeloma Wed, 28 Jul 2010 04:00:00 PDThttp://mnt.to/f/3GGzhttp://mnt.to/f/3GGzRituximab (MabThera, Roche Products) will now be routinely available to certain NHS patients with chronic lymphocytic leukaemia, thanks to final guidance published today (28 July). The NHS has three months to begin implementing this new guidance...Lymphoma / Leukemia / Myeloma Wed, 28 Jul 2010 01:00:00 PDThttp://mnt.to/f/3GF7http://mnt.to/f/3GF7Biovest International, Inc. (OTCQB: "BVTI) announced that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug Designation to BiovaxID®, Biovest's personalized cancer vaccine, for a second lymphoma indication: mantle cell lymphoma. Mantle cell lymphoma is an aggressive and lethal B-cell blood cancer for which there is no current consensus standard-of-care...Lymphoma / Leukemia / Myeloma Tue, 27 Jul 2010 01:00:00 PDThttp://mnt.to/f/3GBRhttp://mnt.to/f/3GBROnyx Pharmaceuticals, Inc. (Nasdaq: ONXX) announced positive top-line results from the Phase 2b 003-A1 study of single-agent carfilzomib, a selective, next generation proteasome inhibitor, in patients with relapsed and refractory multiple myeloma...Lymphoma / Leukemia / Myeloma Sun, 25 Jul 2010 00:00:00 PDThttp://mnt.to/f/3GxXhttp://mnt.to/f/3GxXCytRx Corporation (NASDAQ: CYTR), a biopharmaceutical company specializing in oncology, announced that a 44-year-old female patient with advanced acute promyelocytic leukemia (APL) achieved molecular complete remission with no evidence of disease in the blood cells and/or bone marrow following treatment with CytRx's oncology drug candidate tamibarotene...Lymphoma / Leukemia / Myeloma Sat, 24 Jul 2010 00:00:00 PDThttp://mnt.to/f/3GwLhttp://mnt.to/f/3GwLA five-year study into the causes of deaths of workers at Paducah Gaseous Diffusion Plant (PGDP) shows significantly lower death rates from all causes and cancer in general when compared to the overall United States population. This is known by occupational health researchers as the "healthy worker effect"...Lymphoma / Leukemia / Myeloma Thu, 22 Jul 2010 01:00:00 PDThttp://mnt.to/f/3GqThttp://mnt.to/f/3GqTScientists at the UCLA Broad Stem Cell Research Center have described a population of cells that mark the very first stage of differentiation of human embryonic stem cells as they enter a developmental pathway that leads to production of blood, heart muscle, blood vessels and bone...Stem Cell Research Wed, 21 Jul 2010 05:00:00 PDThttp://mnt.to/f/3Gn5http://mnt.to/f/3Gn5J. Eric Bubbers, PhD, of the Saban Research Institute at Childrens Hospital Los Angeles, has received a $410,000 grant from Phase One Foundation. The award will fund a "first in childhood leukemia" multi-site study in children with relapsed or refractory acute lymphocytic leukemia (ALL) or acute myelogenous leukemia (AML). Dr...Lymphoma / Leukemia / Myeloma Wed, 21 Jul 2010 00:00:00 PDThttp://mnt.to/f/3GmWhttp://mnt.to/f/3GmWCytRx Corporation (NASDAQ: CYTR), a biopharmaceutical company specializing in oncology, announces progress with its clinical program to evaluate the preliminary efficacy and safety of its drug candidate bafetinib in three oncology indications...Lymphoma / Leukemia / Myeloma Tue, 20 Jul 2010 02:00:00 PDThttp://mnt.to/f/3GjMhttp://mnt.to/f/3GjMResearchers at Duke University Medical Center have identified a mechanism that could explain how patients move into the worst phase of chronic myelogenous leukemia (CML). Their findings implicate a protein called Mushashi that prevents cells from maturing, creating a large population of immature cells, which is one of the hallmarks of CML...Lymphoma / Leukemia / Myeloma Tue, 20 Jul 2010 02:00:00 PDThttp://mnt.to/f/3GjXhttp://mnt.to/f/3GjXA genetic clue uncovered by Dana-Farber Cancer Institute scientists enables doctors to predict, for the first time, which children with T-cell acute lymphoblastic leukemia (T-ALL) are unlikely to benefit from standard chemotherapy for the disease and should therefore be among the first to receive new treatments in future clinical trials...Lymphoma / Leukemia / Myeloma Sat, 17 Jul 2010 01:00:00 PDThttp://mnt.to/f/3Gdzhttp://mnt.to/f/3GdzScott & White's Cancer Research Institute (CRI) is conducting a clinical trial that targets malignant T-cell lymphoma, a type of blood cancer. Lymphoma, which affects the white blood cells that normally protect against illness, is categorized either as B-cell or T-cell. About 85% of lymphomas are of B-cell origin, and 15% of T-cell origin...Lymphoma / Leukemia / Myeloma Fri, 16 Jul 2010 00:00:00 PDThttp://mnt.to/f/3G9Nhttp://mnt.to/f/3G9NThe leukemia stem cell - the root cause of all acute leukemias - represents a small population of cells in patients that are difficult to eliminate with standard treatments available today. Though current chemotherapy can produce temporary remission in leukemia survivors, they remain at risk of experiencing a recurrence and dying from the disease...Lymphoma / Leukemia / Myeloma Wed, 14 Jul 2010 02:00:00 PDThttp://mnt.to/f/3G4Nhttp://mnt.to/f/3G4NEntreMed, Inc. (Nasdaq: ENMDD), announced the publication of preclinical data for its Phase 2 oncology drug candidate, ENMD-2076 an Aurora A/angiogenic kinase inhibitor, which demonstrated significant activity against multiple myeloma (MM) cell lines and in MM models in vivo. Results of the study, conducted by EntreMed's collaborator, Sherif Farag, M.D., Ph.D...Lymphoma / Leukemia / Myeloma Wed, 14 Jul 2010 01:00:00 PDThttp://mnt.to/f/3G4chttp://mnt.to/f/3G4cAsuragen, Inc. and Life Technologies Corporation (NASDAQ: LIFE) announced that they have achieved CE-marking and commercial launch in Europe of the BCR/ABL1 Quant™ Test, Asuragen's clinically validated and cGMP manufactured test intended to aid clinicians in the monitoring and treatment of individuals afflicted with chronic myeloid leukemia (CML)...Lymphoma / Leukemia / Myeloma Wed, 14 Jul 2010 00:00:00 PDThttp://mnt.to/f/3G3Rhttp://mnt.to/f/3G3RThe transplantation of stem cells from a healthy donor (allogeneic) offers the chance of cure for patients with an aggressive form of chronic lymphocytic leukemia (CLL), irrespective of genetic prognostic factors and the prior course of the disease. The German CLL Study Group proved this in a multicentric clinical phase II study led by Professor Dr...Lymphoma / Leukemia / Myeloma Tue, 13 Jul 2010 05:00:00 PDThttp://mnt.to/f/3G3thttp://mnt.to/f/3G3tMiss Marple notwithstanding, arsenic might not be many people's favorite chemical. But the notorious poison does have some medical applications. Specifically, a form called arsenic trioxide has been used as a therapy for a particular type of leukemia for more than 10 years...Cancer / Oncology Tue, 13 Jul 2010 05:00:00 PDThttp://mnt.to/f/3G3Fhttp://mnt.to/f/3G3F A new study by researchers from the John Theurer Cancer Center at Hackensack University Medical Center sheds light on how bortezomib (VELCADE®), the first in a new class of cancer drugs known as proteasome inhibitors, works in mantle cell lymphoma. The study also provides preliminary evidence for which patients might benefit most from bortezomib...Lymphoma / Leukemia / Myeloma Mon, 12 Jul 2010 05:00:00 PDThttp://mnt.to/f/3FYXhttp://mnt.to/f/3FYXBristol-Myers Squibb Company (NYSE: BMY) and Otsuka Pharmaceutical Co., Ltd. announced that the U.S. Food and Drug Administration (FDA) has accepted for filing and review the supplemental New Drug Application (sNDA) for SPRYCEL® (dasatinib) for the treatment of adult patients with newly diagnosed chronic myeloid leukemia (CML) in chronic phase...Lymphoma / Leukemia / Myeloma Mon, 12 Jul 2010 02:00:00 PDThttp://mnt.to/f/3FYthttp://mnt.to/f/3FYtA completely new mechanism that leads to the development of a certain type of leukaemia could eventually be targeted by new treatments, according to research published in Nature Immunology 1...Lymphoma / Leukemia / Myeloma