The world’s first ever analysis of data from a full scale clinical trial in adults shows that training Health Visitors to assess and psychologically support mothers after childbirth can prevent the development of depression over the following year.

But the substantial reduction in the number of NHS health visitors was identified by researchers as a key issue for the health and well-being of mums.

The prevention study was led at the University of Leicester by Professor Terry Brugha with researchers from the universities of Nottingham and Sheffield. It is being published in the Cambridge University Press journal Psychological Medicine.

While small scale studies have been carried out into the prevention of depression among adults, this peer refereed scientific report is the first sufficiently large scale randomised trial to clearly show a statistically significant reduction in future cases of depression in women living in the community who were not depressed when they joined the study.

  • Intervention women, who had a Health Visitor with additional mental health training, were 30% less likely to have developed depression six months after child birth compared to control women receiving usual care.
  • The results suggest that these improvements continued throughout the eighteen month follow-up. Even women who had few or no complaints of depression at six weeks following child birth appeared to benefit later if their Health Visitor had additional training.
  • If the Health Visitor with additional training discussed the results of depression screening with the mother at six weeks it appears there was even more benefit and less risk of developing later depression.
  • There was evidence that the training programme was also cost effective even when the cost of extra training was taken into account. Health visitors with the new training were found to spend less general time with mothers but more time with those who needed emotional support.
  • In discussing the findings the investigators considered that the quality of the ongoing relationship between the Health Visitor and mother, which can continue until the child starts to attend school, may have provided the mother with a reliable confidant she knew she could turn to later if necessary. It may also have helped to know that she would not have to discuss emotional concerns with a different person such as her doctor or a psychologist and that access to help would be easy and non stigmatizing.
  • The investigators were successful in obtaining further funding to undertake similar research in Leicestershire and Northamptonshire but were unable to do so because of the critical reduction in the number of Health Visitor Staff available. Health Visitors told them that they wanted to receive such training and to support such research but they were struggling to provide a minimum of one home visit for each new childbirth.

Depression is thought to affect about one in ten women following child birth, depending on the definition and method used to assess depression. The consequences for the child and family are even more profound and concerning than when depression affects adults at other times.

The World Health Organisation has predicted that depression will be a leading cause of disability due to ill health by the year 2020. Although depression can be treated effectively with medication and psychological approaches there is no evidence that rates of depression have fallen since these treatments became available. It is also often the case that once treatment is stopped the condition can relapse.

The prevention study involved analysing data already collected as part of the PoNDER clinical trial originally designed to test the effectiveness of health visitors identifying and managing postnatal depression following child birth. Dr Jane Morrell, now at the University of Nottingham, was Principal Investigator for the PoNDER trial with a team of researchers at the Universities of Sheffield (Jane Morrell, Pauline Slade, Stephen Walters), Leicester and Leeds, with funding from the NIHR Health Technology Assessment programme , London.

While the PoNDER treatment trial was published in the BMJ in 2009, the research into prevention of depression required additional collaborative analysis by the authors of this new scientific paper which is now published separately in the Cambridge University Press journal Psychological Medicine.

“Universal prevention of depression in women postnatally: cluster randomized trial evidence in primary care”, appears in the journal Psychological Medicine (2010) Vol 40. Cambridge University Press, doi:10.1017/S0033291710001467 at (

Source: University of Leicester