The researchers say the model that is used to estimate the potential cancer risk of low-level radiation from medical imaging machines - such as this CT scanner - is wrong and should be abandoned.
Writing in the American Journal of Clinical Oncology, the researchers describe how the linear no-threshold model (LNT) - first proposed over 70 years ago - is used to estimate cancer risks from low-dose radiation, such as medical imaging.
But - say James Welsh, a radiation oncology professor in the Stritch School of Medicine at Loyola University, Chicago, IL, and colleagues - risk estimates based on the LNT model are only theoretical, and, as yet, "have never been conclusively demonstrated by empirical evidence."
They say persistent use of the LNT model by regulators and advisory bodies leads to unfounded fears and money being wasted on unnecessary safety measures.
As a result, many doctors are averse to recommending and using the most appropriate imaging procedures for their patients, and many patients are unnecessarily scared to undergo them.
Model ignores that human body repairs low-dose radiation damage
The LNT model maintains there is no safe dose of radiation - no matter how low the dose. It says you can work out the cancer risk of very low-dose radiation exposure by simply continuing in a straight line from the well-established, undisputed effects of high-dose radiation.
But such a model ignores the fact that the human body is able to repair damage caused by low-dose radiation - something that has evolved over millennia in humans and other organisms that are continually exposed to naturally occurring radiation in the environment. The authors note:
"We are literally bathed every second of every day in low-dose radiation exposure due to natural background radiation, exposures that vary annually from a few mGy to 260 mGy, depending upon where one lives on the planet."
They go on to explain how no associated health effects as a result of being exposed to this background radiation have been documented anywhere in the world.
In fact, people in countries like the US are living longer than ever - likely because of improvements in medical care that involve exposure to radiation from diagnostic equipment - e.g. X-rays or computed tomography (CT) scans - at doses well below those of the background radiation.
In their paper, the authors describe how they revisited the studies - from over 70 years ago - that led to widespread use of the LNT model.
Low-dose risks are not an extrapolation of high-dose risks
The studies - published in the 1940s - exposed fruit flies to various doses of radiation, but not very low doses. Nevertheless, they concluded that to estimate the risk of those effects occurring at low doses, you simply continued in a straight line down the plot result from the higher-dose experiments.
When scientists carried out the same experiments on fruit flies in 2009 - using low doses of radiation - they did not find the results to be as predicted by the original studies.
Also, note the authors, studies of human populations exposed to radiation - including nuclear bomb survivors - have never conclusively shown that low-dose radiation increases cancer risk.
They urge people to vigorously challenge any claim that low-dose radiation from medical imaging is known to cause cancer.
To back such claims only "serves to alarm and perhaps harm, rather than educate," they note, as they conclude that the LNT model "should finally and decisively be abandoned."
Meanwhile, Medical News Today recently learned how scientists have discovered a surprising new clue to how cancer tumors form. It appears that a small minority of cancer cells extend "cellular cables" to draw in nearby cells - including a lot of healthy cells - into the tumor.