Insulin is a hormone that takes sugar from foods and moves it to the body's cells. If the body does not make enough insulin or does not use insulin well, the sugar from food stays in the blood and causes high blood sugar.
Diabetes is a key health concern worldwide. In the United States, the rate of new cases rose sharply from the 1990s, but it fell between 2008 and 2015, and it continues to fall, according to the Centers for Disease Control and Prevention's (CDC) National Diabetes Report, 2017.
The most common of diabetes is type 2. According to the CDC, 90 to 95 percent of people with diabetes in the United States have type 2. Just 5 percent of people have type 1.
Type 2 diabetes is the most common form of diabetes.
Diabetes is at an all-time high in the U.S. The CDC's Division of Diabetes Translation states that 1 percent of the population, which is about a half of a million people, had diagnosed diabetes in 1958.
In 2015, around 9.4 percent of the population in the U.S. had diabetes, including 30.2 million adults aged 18 years and over. Nearly a quarter of these people do not know they have it.
The ADA report that the number of people who have diabetes increased by 382 percent from 1988 to 2014.
The risk of developing diabetes increases with age.
The CDC report that 4.0 percent of people age 18-44 years are living with diabetes, 17 percent of those aged 45 to 64 years, and 25.2 percent of those aged over 65 years old.
Type 2 diabetes is thought to result from a combination of genetic and lifestyle factors.
The exact cause is unknown, but risk factors appear to include:
- excess body fat
- high blood pressure or cholesterol
- having a close family member with the condition
- a history of gestational diabetes
- higher age
As obesity has become more prevalent over the past few decades, so too has the rate of type 2 diabetes. In 2013, more than 1 in 3 people in the U.S. were considered to have obesity, and over 2 in 3 were either overweight or had obesity.
In 1995, obesity affected 15.3 percent of Americans, and in 2008, the figure was 25.6 percent. From 1998 to 2008, the incidence of diabetes increased by 90 percent.
Although the link between obesity and diabetes is well known, the reasons they are connected remain unclear. A report in the Journal of Clinical Endocrinology and Metabolism asks why obesity does not always lead to diabetes, given the established link between the two conditions.
The same report notes that the location of body fat appears to play a role. People with more fat in the upper body area and around the waist are more likely to get diabetes than those who carry their body fat around the hips and lower body.
Diabetes and ethnicity
Rates of diabetes vary between ethnic groups.
There may be a combination of factors, including:
- health conditions
- access to healthcare
The CDC's National Diabetes Statistics Report, 2017, found that, among people aged 20 years and over, diabetes affects:
- 7.4 percent of Non-Hispanic whites
- 8.0 percent of Asian Americans
- 12.1 percent of Hispanics
- 12.7 percent of Non-Hispanic Blacks
- 15.1 percent of American Indians and Alaska Natives
Why diabetes is serious
Diabetes can have serious health consequences.
According to the CDC, 79,353 deaths occur each year due to diabetes. The number of fatalities related to diabetes may be underreported.
Why and how does diabetes damage the body and cause complications?
The ADA says:
- Adults with diabetes are significantly more likely to die from a heart attack or stroke.
- More than a quarter of all Americans with diabetes have diabetic retinopathy, which can cause vision loss and blindness.
- Each year, nearly 50,000 Americans begin treatment for kidney failure due to diabetes. Diabetes accounts for 44 percent of all new cases of kidney failure.
- Each year, diabetes causes about 73,000 lower limb amputations, which accounts for 60 percent of all lower limb amputations (not including amputations due to trauma).
Because of its high prevalence and link to numerous health problems, diabetes has a significant impact on healthcare costs.
The productivity loss for reduced performance at work due to diabetes in 2012 was 113 million days, or $20.8 billion, according to the ADA.
Diabetes cost the U.S. $245 billion in 2012. But, the ADA believes this number may be lower than the actual cost because it does not include:
- the millions of people who have diabetes but are undiagnosed
- the cost for prevention programs for people with diabetes, which are not counted under standard medical costs
- over-the-counter medications for eye and dental problems, which are more common in people with diabetes.
- administrative costs for insurance claims
- the cost of reduced quality of life, pain and suffering, lost productivity of family members, and other factors that cannot be measured directly
Because diabetes affects various parts of the body, the medical costs span different areas of specialty. The ADA report that:
- 30 percent of medical costs associated with diabetes are for circulation problems that reduce blood flow to the limbs
- 29 percent of medical costs associated with diabetes are for kidney conditions
- 28 percent of medical costs associated with diabetes are for nervous system conditions
Despite its complications, people can manage their diabetes with a comprehensive plan that includes lifestyle changes and proper medical care. If they control their blood sugar levels well, many people with diabetes can lead full, active lives.
Difference between types 1 and 2
In type 1 diabetes, the immune system attacks the cells in the pancreas that make insulin. As a result, the body does not produce insulin, and people with this condition must take insulin by injection or pump every day.
Type 1 diabetes usually develops in children or young adults, but it can occur at any age. There is no known way to prevent type 1 diabetes, and there is no cure.
In 2011-2012, around 17,900 children under the age of 18 years received a diagnosis of type 1 diabetes in the U.S., or around 49 children each day. Type 1 diabetes affects around 1.25 million American adults and children.
People with type 2 diabetes may still have insulin in their bodies, but not enough for proper blood sugar control. Or, the body may not be able to use the insulin it has properly. As a result, blood sugar levels can become too high.
Typically, adults are diagnosed with type 2 diabetes, but children can get it too. Certain factors increase a person's risk of getting type 2 diabetes, including:
- older age
- a family history of diabetes
- lack of exercise
- problems with glucose metabolism
The annual relative increase for type 1 diabetes in 2002-2012 in the U.S. was 1.8 percent, but the annual increase for type 2 diabetes was 4.8 percent.