We include products we think are useful for our readers. If you buy through links on this page, we may earn a small commission. Here’s our process.

Medical News Today only shows you brands and products that we stand behind.

Our team thoroughly researches and evaluates the recommendations we make on our site. To establish that the product manufacturers addressed safety and efficacy standards, we:
  • Evaluate ingredients and composition: Do they have the potential to cause harm?
  • Fact-check all health claims: Do they align with the current body of scientific evidence?
  • Assess the brand: Does it operate with integrity and adhere to industry best practices?
We do the research so you can find trusted products for your health and wellness.
Was this helpful?

Lips can become swollen if fluid builds up in the skin tissue or if there is underlying inflammation. Causes include allergic reactions, angioedema, and injuries.

Swollen lips have a range of causes, which vary from normal to potentially dangerous.

In this article, we look at what causes swollen lips, how to treat them, and when to see a doctor.

Swollen lipsShare on Pinterest
Additional symptoms of swollen lips may include soreness or cracked skin.

There are a range of causes for swollen lips with different symptoms, including skin conditions and severe allergic reactions.

It is essential for people with swollen lips to identify their specific symptoms and potential causes so that they can receive appropriate treatment.

Additional symptoms can include:

  • redness
  • soreness
  • sensitive to the touch
  • cracked skin

Often, lips swell because of an allergic reaction to substances in the environment, foods, or medications. These three triggers are discussed below.

An allergic reaction is an immune system response that occurs when the body reacts negatively to a certain substance.

When a person has an allergic reaction, certain cells in the body produce and release a chemical called histamine.

Histamine’s job is to protect the body, but in doing so, it causes swelling and often itching as part of an inflammatory response.

The American College of Allergy, Asthma, and Immunology (ACAAI) estimate that more than 50 million Americans have some form of allergy.

People can be allergic to many different things, but some common allergies that can cause swollen lips include:

Environmental allergies

Environmental allergies are allergic reactions to substances found in the environment.

Common allergies include pollen, mold spores, dust, and pet dander (tiny particles of skin shed by an animal).

Symptoms of an environmental allergy include:

  • swelling of the lips and other areas of the body
  • wheezing
  • hives
  • sneezing
  • a blocked nose

Depending on the severity of the allergic reaction, a person can often treat the allergy with an over-the-counter antihistamine. These are also available to purchase online.

In more serious cases, a person can get a series of allergy shots, also called immunotherapy, to help the body get used to the allergens.

Food allergies

Share on Pinterest
Swollen lips may be caused by food allergies.

The ACAAI report that between 4 and 6 percent of children and around 4 percent of adults have a food allergy.

Allergies tend to run in families, but it is impossible to predict if a parent will pass an allergy on to their child.

About 90 percent of food allergies involve the following foods:

  • eggs
  • milk
  • peanuts and tree nuts
  • fish and shellfish
  • wheat
  • soy

Besides swollen lips, the ACAAI list the following symptoms of food allergies:

  • vomiting
  • stomach cramps
  • hives
  • shortness of breath
  • wheezing
  • cough
  • swollen tongue
  • trouble swallowing
  • weak pulse
  • pale or blue skin
  • dizziness

The main way to manage a food allergy is to avoid the food that triggers it. This can involve reading labels carefully and asking about ingredients at restaurants.

A dietitian or nutritionist can often advise on the best course of action regarding a diet for a specific allergy.

Other allergies

Insect bites, stings, and allergies to specific drugs can also cause the lips to swell.

Some people have allergies to particular medications; with antibiotics, particularly penicillin, being the main culprit.

Other common symptoms of a penicillin allergy include:

  • rashes
  • itchy eyes
  • hives
  • wheezing
  • swollen tongue or face
  • feeling sick
  • vomiting
  • diarrhea
  • headache

If a person experiences these symptoms after taking a medication that contains penicillin, they should stop taking it immediately and consult their doctor. Other medication options are often available.

Other drugs that can cause an allergic reaction that may be like this include non-steroidal anti-inflammatory drugs, anticonvulsants, and drugs associated with chemotherapy.


Share on Pinterest
An EpiPen is the first course of action, if swollen lips are caused by anaphylaxis.

Serious allergic reactions can be in the form an acute allergic reaction, called anaphylaxis. When anaphylaxis is severe, a person can have anaphylactic shock.

This reaction can be dangerous and, according to the American Academy of Allergy, Asthma, and Immunology (AAAAI), even fatal. Some people may not even realize they have an allergy to something until they experience anaphylaxis.

The AAAAI list five groups of symptoms of anaphylaxis:

  1. Breathing. Wheezing, tight throat, chest pain, difficulty swallowing, blocked nose.
  2. Circulation. Pale or blue skin, weak pulse, light-headedness, low blood pressure.
  3. Skin. Hives, swelling, itchiness, warmness, redness, a rash.
  4. Stomach (abdomen). Nausea, cramps, vomiting, diarrhea.
  5. Other. Symptoms include anxiety, a headache, and itchy red eyes.

Anaphylaxis requires immediate medical treatment. The first course of action is to inject a dose of epinephrine, such as through an EpiPen, and then to get to an emergency room.

Aside from allergies, some other things can cause swollen lips. These include:


This is typically a short-term condition that happens when there is swelling under the skin.

It often occurs as an adverse side effect of a medication or in response to a trigger that causes an allergy.

Angioedema often affects the lips along with other body parts, including:

  • hands
  • feet
  • around the eyes
  • tongue
  • genitals

Angioedema is not considered to be a serious condition, and it will usually go away on its own within a few days.

If angioedema is caused by an allergy, then an antihistamine is the usual treatment method.

If it is caused by a medication, a person may need to stop the current course of treatment and see their doctor to find an alternative.


Minor cuts, wounds, and lacerations to the lips can result in them becoming swollen. The lips have a rich blood supply, and so they are susceptible to swelling.

To treat lip injuries, clean the area and stop any bleeding with a clean cloth or bandage. It is also possible to reduce swelling by applying an ice pack to the affected area.

If the injury is large, was caused by an animal bite, is extremely painful, or is showing signs of infection, then the person should seek help from a healthcare professional.

Rare medical conditions

A rare condition that can cause swollen lips is granulomatous cheilitis.

  • Granulomatous cheilitis is a lumpy swelling of the lips. Causes include an allergy, Crohn’s disease, sarcoidosis, or orofacial granulomatosis.
  • Miescher-Melkersson-Rosenthal syndrome is a recurrent, long-lasting swelling of one or both lips (granulomatous cheilitis) with facial muscle weakness and a fissured tongue. There is no known cause, though genetics may be a factor.

Both conditions can usually be treated with prescription medication, although in some cases surgical reduction may be required. If there is an underlying cause, treatment should address it.

There are several reasons as to why lips become swollen, but in most cases, it is not serious and will disappear on its own.

Anyone with swollen lips should see a doctor if they are experiencing severe symptoms, such as those associated with anaphylaxis.

Most cases of swollen lips do not require emergency care, however, and will often go away on their own within a few days.

Identifying the underlying cause of swollen lips is essential. If a person requires treatment, such as in the case of an allergy, they should see a doctor for an accurate diagnosis.