Livedo reticularis, commonly known as mottled skin, causes patterned areas to appear on the skin. It may result from reduced blood flow to the skin, for example, because of a health condition or cold weather.
When a person has livedo reticularis a blotchy or web-like pattern of red, blue, or purple lines appears across the skin. In very deep skin tones, the pattern may be a dark brown.
Because mottled skin is not a medical term, people may also use it to describe several other skin conditions and rashes. This article will focus on mottled skin caused by livedo reticularis.
Mottled skin is a net or web-like pattern on the skin. This pattern will usually appear red, bluish, purple, or brown.
The medical name for this symptom is livedo reticularis.
The main types of livedo reticularis are:
- Physiologic livedo reticularis/cutis marmorata: A temporary reaction to the cold that comes and goes. It commonly affects children and babies, but may also affect adults.
- Primary or idiopathic livedo reticularis: Mottled skin that does not have a cause.
- Secondary livedo reticularis: Mottled skin caused by an underlying condition.
If the rash is associated with systemic symptoms, doctors must check whether the rash is livedo reticularis or livedo racemosa, a related condition that also causes mottling. Livedo racemosa is always the result of an underlying condition and has a strong association with antiphospholipid syndrome (APS).
Many things can reduce the flow of oxygenated blood to the skin, so many things can cause livedo reticularis. Doctors sort cases into different categories to make it easier to understand the potential causes.
Below are a few of the causes associated with mottled skin.
Physiologic livedo reticularis, or cutis marmorata, can occur when blood vessels constrict in response to the cold. As the skin warms up, the blood vessels open again, which leads to the mottled skin clearing up.
This can affect both adults and children, but it is more
This is a harmless condition that does not require treatment. People can reduce their symptoms by warming their skin.
APS, or Hughes syndrome, is an autoimmune condition that mostly affects young to middle-aged adults. In this condition, abnormal antibodies can lead to abnormal micro blood clots, which decrease blood flow and increase the risk of stroke and pulmonary embolism.
Mottled skin, along with red or purple skin patches, is a common symptom of APS. A person
- blood circulation problems
- blood clots
- leg ulcers
Research also shows that APS can be an underlying condition in people with Snedden syndrome, a disorder in which abnormal clotting leads to neurological symptoms. This condition can also cause mottled skin.
People who have APS also have an increased risk of developing deep vein thrombosis. For this reason, many people with this diagnosis need blood-thinning medications to help prevent dangerous blood clots.
Other underlying conditions
The causes of secondary livedo reticularis are usually underlying diseases or disorders. These include:
- unexplained weight gain
- low energy
- sensitivity to cold
Diseases affecting the parathyroid gland may also cause mottled skin, especially when blood vessels calcify, damaging circulation.
Treatment for thyroid disease focuses on correcting a person’s thyroid hormone levels. People with hypothyroidism will need to take synthetic thyroid hormones.
It may also cause dark, patchy, or mottled skin, which may be due to the way the inflammatory condition affects the blood vessels.
Other symptoms of RA
- a low fever
- pain and stiffness that lasts for more than 30 minutes
- weight loss
- firm lumps or nodules beneath the skin in the hands, elbows, or ankles
There is no cure for RA, but treatment can reduce the symptoms and the risk of joint damage. Doctors can prescribe disease-modifying antirheumatic drugs (DMARDs), biologics, and pain medications to reduce autoimmune activity and manage people’s symptoms.
A 2020 case study notes that skin symptoms may occur in as many as
Doctors do not know what specifically caused the rashes in these people. It may be part of an immune reaction or related to new medications for COVID-19.
Other symptoms of COVID-19
- a cough
- a new loss of taste or smell
- feeling short of breath
- body aches
- a sore throat
- congested or runny nose
- a headache
If someone could have COVID-19, they need to remain at home and seek testing from their local health authority, even if their symptoms are mild. Most cases of COVID-19 improve on their own without treatment, but people must seek emergency help if someone develops:
- difficulty breathing
- blue or white lips
- new confusion
- pain or pressure in the chest
- difficulty staying awake
A person can receive a vaccine against COVID-19.
Mottled skin is a secondary and rare symptom of acute pancreatitis. This condition happens when the pancreas becomes inflamed for a short period.
- severe abdominal pain
Treatments for acute pancreatitis include intravenous (IV) fluids and anti-inflammatory medication. Lifestyle changes may also help prevent it from coming back.
Lupus is an autoimmune inflammatory condition in which the immune system begins attacking healthy tissue. If lupus causes damage to the small blood vessels, a person with this condition may develop livedo reticularis.
Other symptoms of lupus include:
- a butterfly-shaped rash on the face
- dry eyes
- breathing problems
- oral ulcers
In addition to cold and mottled skin, symptoms of septic shock can include:
- difficulty breathing
- rapid heart rate
- rapid breathing
- nausea or vomiting
If someone seems as though they are in septic shock, contact emergency services immediately.
Treatment may include oxygen, IV fluids, and further testing. A person may also need treatment for the underlying cause of their septic shock, usually an infection.
People should speak with a doctor if they have mottled skin and are not sure why. A doctor may:
- perform a physical examination
- take a complete medical history
- request blood work to check for infections and illnesses
- perform a skin biopsy for further evaluation
A doctor will also ask when the symptoms began and if other symptoms are present to determine the source of the problem. For example, a person with an infection who seems confused may have septic shock, while a newborn baby may have developmentally typical skin mottling.
Depending on what is causing it, mottled skin is not always preventable. However, if someone has cutis marmorata or another condition that affects body temperature or circulation, taking steps to stay warm and boost blood flow may help.
People can try:
- Staying active: Regular exercise can help improve circulation. Avoid sitting or lying down for long periods, wherever possible. If this is unavoidable, take regular breaks to stretch and move around. People with limited mobility may find it helpful to elevate their feet.
- Keeping warm: Wearing multiple, light layers of clothing is a more effective way to stay warm than wearing just one thick layer. A blanket may help keep the legs and feet warm when sitting. Putting on gloves before going outside in cold weather traps warm air.
- Reducing pressure on the extremities: Try to avoid putting weight on the arms or legs for long periods. For example, if someone often sits with their legs crossed, they could try uncrossing them to allow blood to flow more easily. Wearing tight clothing may also reduce blood flow, so aim for clothes that fit but do not dig in.
- Massage: Massage can help stimulate circulation. A person can visit a professional for this or learn self-massage techniques.
- Maintaining hydration: Making sure a person drinks enough water can help support healthy blood flow.
- Stress reduction: When a person experiences stress, it can cause the blood vessels to narrow and restrict blood flow. Therefore, managing a person’s stress is a good prevention strategy.
- Quitting smoking: Smoking can also cause blood vessels to narrow, so a person should avoid it as well.
The following are answers to common questions about mottled skin.
Why does a baby have mottled skin?
Mottled skin in newborn babies is usually the result of cutis marmorata. It is a typical physiological response to cold temperatures and does not require treatment. Babies will usually grow out of cutis marmorata within a few weeks or months, but it can persist into adulthood. Rarely, mottled skin in babies can occur because of cutaneous marmorata telangiectatica congenita, a genetic condition that causes blood vessels to form differently than usual.
Why do some people get mottled skin before death?
The skin may appear mottled when a person is close to dying, particularly if it affects the upper extremities. Mottled skin may persist after someone dies because the heart stops pumping, so the circulation stops.
Should I worry about livedo reticularis?
A person with mottled skin may want to see a doctor who can rule out any underlying cause, especially if they are also experiencing other symptoms. However, in many cases, it may be a harmless symptom with no obvious cause or just a response to cold temperature.
Mottled skin is not harmful by itself. Some people develop this symptom when they are cold. Others have idiopathic livedo reticularis, meaning the mottled skin occurs on its own and has no clear cause.
Mottled skin can vary in severity. The more severe it is, the more likely it is that it is a symptom of another condition.
It is associated with thyroid disease, acute pancreatitis, and shock. If it is a sign of an underlying disorder, there will typically be other symptoms that occur alongside skin mottling.
People with mottled skin as a result of cold temperatures may be able to ease this symptom by boosting circulation and warming their skin. If warming their skin does not help, or the mottled skin is unconnected to temperature, it is a good idea to speak with a doctor.