Psoriasis is a life-long, autoimmune inflammatory disease. It often appears as a skin condition, but it is a systemic condition that can affect many parts of the body.
Not only are there are different types of psoriasis, but it is also a complex condition.
As scientists learn more about inflammatory conditions and how they affect people, they are also establishing more links between conditions that have different diagnoses.
In addition, psoriasis poses lifestyle challenges that can be difficult to cope with. This can lead to additional symptoms, such as depression.
Read on to find out more about some of the problems that may occur alongside this condition.
People with psoriasis are more likely to have antibodies for celiac disease, suggesting that there may be a link between the two.
Celiac disease affects around
People with celiac disease can experience a severe reaction when they consume gluten.
Both celiac disease and psoriasis appear to stem from dysfunction in the immune system. Some people find that avoiding gluten helps to reduce the symptoms of psoriasis.
Researchers who published a
In 2014, authors of a
People with psoriasis who are considering giving up gluten should speak to a doctor first, as whole grains can contain valuable nutrients, and a gluten-free diet may not be suitable for everyone.
Some studies have suggested that people with psoriasis are more likely to develop problems with mucous membranes in the oral cavity, such as fissures in the tongue and lesions in the gums and cheeks.
Scientists have not established a specific link between psoriasis and oral problems, but
Psoriasis and mouth problems could stem from similar genetic factors, or they might result from exposure to similar triggers, such as stress and alcohol.
Scientists have looked at possible links between psoriasis and inflammatory bowel disease (IBD), Crohn's disease, and ulcerative colitis.
Psoriasis and IBD have various genetic factors in common.
Studies have found that vitamin D deficiency is often present at the onset of some autoimmune diseases.
Some experts recommend taking vitamin D supplements to improve the symptoms of psoriasis.
However, they note that the association between vitamin D and psoriasis is "controversial."
Another study, also published in 2018, looked at 61 people with psoriasis and 61 people without. The researchers found no correlation between vitamin D levels and the severity of psoriasis symptoms in the two groups.
The results were published in the
One reason may be the use of systemic medications in treatment. These drugs affect the whole body.
Other underlying reasons may include genetic factors and the impact of psoriasis on the individual's lifestyle. More research is necessary to confirm a link.
Experts do not know what might link these conditions with psoriasis. There
People with moderate-to-severe psoriasis should undergo testing for these conditions, so that they can receive preventive treatment if necessary.
Some types of psoriasis can affect body temperature regulation, and this can have an impact on internal organs, such as the heart and the kidneys, according to the National Psoriasis Foundation.
The skin is important for keeping the body temperature stable, and problems that affect the skin can also affect temperature, especially with more severe forms, such as erythrodermic and pustular psoriasis.
Pustular psoriasis is a severe form of psoriasis that can appear in people who already have psoriasis.
One type, known as Zumbusch psoriasis, can lead to severe erythroderma and skin scaling.
The patient who was the focus of the study had the following symptoms:
- pustular skin lesions
- pitted nail beds
- fever and chills
- muscle weakness
- a rapid heartbeat
- difficulty breathing
- an over-accumulation of fluids, or edema
The person may need to spend time in the hospital until treatment normalizes their fluid, chemical balances, heart function, and skin condition.
It usually appears between the ages of 30 and 50 years.
While 85 percent of people with this condition first have skin symptoms, it can occur before or without dermatological symptoms.
- pain and swelling over the tendons
- swollen fingers and toes
- reduced mobility
- stiffness and pain in one or more joints
- pitted nails that may look as if they have a nail fungus
There are also different types of PsA, including:
- spondylitis, which affects the spine
- enthesitis, which occurs where the ligaments or tendons meet the bones
- dactylitis, which affects the fingers and toes
Anyone with psoriasis who has joint pain or stiffness should speak to their doctor. Early treatment can reduce the risk of permanent joint damage.
The researchers found that 60 percent of those with PsA had some degree of hearing loss, compared with only 8.3 percent of those without the condition. They concluded that PsA may lead to damage in the inner ear.
Chronic kidney disease appears to be more common among people with psoriasis.
Scientists reporting in 2016 described this as "logical," because psoriasis has links with cardiovascular disease, and kidney disease shares the same risk factors.
In addition, the treatments people use for psoriasis are likely to have a toxic effect on the kidneys.
Living with psoriasis can be difficult, and it can have emotional and social consequences.
In a review published in
People who have visible lesions may feel embarrassed by their appearance. This can lead to isolation, depression. and anxiety.
This can affect areas of life such as:
- leisure and social activities
However, there may also be physiological reasons for the psychological impact of psoriasis.
Scientists have found evidence of adrenal and pituitary involvement, which could lead to a hormonal imbalance. This imbalance could impact both the skin changes and the psychological well-being of a person with psoriasis.
Stress and worry, in turn, can make symptoms worse.
Anyone with psoriasis who is experiencing signs of depression or low mood should speak to a doctor about their concerns.
As doctors increasingly come to understand the mental health challenges that people with psoriasis face, more effective treatment will hopefully become available.
Psoriasis is a complex condition with a wide range of possible complications and comorbidities.
When a person is familiar with the possible problems that can arise, it will be easier for them to explain to their doctor how they feel and to seek help.
Treatment is available that can help to reduce many of the symptoms and complications of psoriasis and to improve a person's quality of life.