ZzzQuil is an over-the-counter nighttime sleep aid. The active ingredient in ZzzQuil is diphenhydramine, which is also the active ingredient in the allergy medication Benadryl.
Diphenhydramine is an antihistamine that people commonly use to treat allergic reactions, itchiness, and hives. The most common side effect of diphenhydramine is drowsiness.
ZzzQuil is a safe and effective medication for treating short-term sleeping difficulties, or insomnia, in people over 12 years old. However, individuals with certain medical conditions, such asthma and heart disease, should speak to a doctor before taking ZzzQuil.
Read on for more information on the uses, dosage, and safety of taking ZzzQuil. We also discuss whether ZzzQuil can be addictive.
The active ingredient in ZzzQuil is an antihistamine called diphenhydramine.
Antihistamines reduce the effect of histamines, which are natural chemicals that the body produces during an allergic reaction.
Diphenhydramine binds to the histamine-1 receptor in the body. This receptor is present in many areas of the body, including the respiratory tract, abdominal tract, immune cells, and brain.
Antihistamines such as diphenhydramine are common ingredients in allergy and cold medications.
The most significant side effect of diphenhydramine is drowsiness, which is due to the effect that some antihistamines can have on the brain.
The manufacturer recommends using ZzzQuil for relieving occasional sleeplessness. ZzzQuil works by helping to reduce the time it takes for a person to fall asleep.
Adolescents and adults can use ZzzQuil as a short-term aid for occasional problems getting to sleep. The manufacturer states that children under the age of 12 years should not use this medication.
The recommended dose of ZzzQuil is 50 mg at bedtime when needed, or as a person’s doctor directs. ZzzQuil is available in both liquid and capsule forms.
For the liquid form, a single 50 milligram dose is equal to 30 milliliters, or 2 tablespoons. Liquid ZzzQuil comes with a special cup for measuring out the correct dose.
For the capsule form, a single 50 mg dose is equal to two ZzzQuil capsules. A person cannot cut, chew, or split the capsules.
People should not take more than 50 mg of ZzzQuil in a single day.
The liquid form of ZzzQuil contains 10% alcohol. ZzzQuil is also available in an alcohol-free liquid solution, which may be more appropriate for adolescents.
Diphenhydramine, which is the active ingredient in ZzzQuil, can cause side effects in some people.
The most common side effects of diphenhydramine
- loss of coordination
- upper abdominal pain
- thickened mucus in the lungs
- dry mouth and nasal passages
- stimulation of the central nervous system
- involuntary muscle movements
- painful or difficult urination
- low blood pressure
- blurred or double vision
- irregular heartbeat
- sensitivity to light
- erectile dysfunction
- early periods
Rarely, more serious side effects can occur,
- severe allergic reactions
- abnormal heart rhythm
The intended use of ZzzQuil is for occasional sleeplessness. The manufacturer recommends that people consult a doctor if they experience sleeping difficulties continuously for more than 2 weeks, as this may be a symptom of a more serious medical condition.
Because ZzzQuil causes drowsiness, it may affect a person’s ability to drive or operate heavy machinery. It is also important to avoid drinking alcohol when taking ZzzQuil as this can increase drowsiness.
Older adults should use ZzzQuil with caution as side effects such as drowsiness, dizziness, and low blood pressure can increase the risk of falling.
Taking ZzzQuil may worsen certain medical conditions,
- heart disease
- high blood pressure
Individuals with these conditions should consult their doctor before taking ZzzQuil.
People who experience urinary difficulties while taking ZzzQuil should stop taking the medication and speak to a doctor.
Not everyone can take ZzzQuil. People should not give ZzzQuil to children under the age of 12 years.
The active ingredient of ZzzQuil can pass into breastmilk, so people who are breastfeeding should consult a doctor before taking it. Pregnant women should also seek medical advice before using this medication.
People taking monoamine oxidase inhibitors (MAOIs), which are a type of antidepressant, should avoid taking ZzzQuil or speak to a doctor first. MAOIs can worsen some of the side effects of antihistamines.
Although ZzzQuil contains diphenhydramine, which can help relieve allergy symptoms, it can still cause allergic reactions in some people. Anyone who has previously had an allergic reaction to ZzzQuil or medicines containing diphenhydramine should avoid taking it.
According to a
Antihistamines are widely available OTC medications. The drowsing effect of antihistamines can help relieve sleeplessness and anxiety.
Taking too much diphenhydramine can cause a calming effect and mild euphoria. Some people misuse diphenhydramine for its hallucinogenic effects, which may occur at doses of
Diphenhydramine is not additive at the recommended dosage. However, taking very large doses of diphenhydramine, such as over
People who become dependent on diphenhydramine can experience withdrawal symptoms when they stop taking it. These may
- worsened sleeplessness
- runny nose
- stomach upset
- abdominal cramps
Doctors usually recommend a gradual dosage reduction schedule for people who become dependent on diphenhydramine. This detox program help treat the person’s dependence and minimizes uncomfortable withdrawal symptoms.
ZzzQuil is a safe and effective medication that can help relieve occasional sleeplessness. However, people should stop using ZzzQuil and see a doctor if sleeping difficulties persist for more than 14 consecutive days.
ZzzQuil is not suitable for everyone. Children under 12 years old should not take ZzzQuil, and women who are pregnant or breastfeeding should speak to a doctor first.
ZzzQuil can also interact with some antidepressants and can worsen certain medical conditions, such as asthma and heart disease. Side effects of ZzzQuil may increase the risk of falls in older people.
ZzzQuil is not addictive at the recommend dosage. However, people who take very high doses of ZzzQuil for a prolonged period may be at risk of becoming dependent.