Amberen Menopause is an over-the-counter product that claims it can relieve menopause symptoms. However, being a dietary supplement, it has not received approval from the Food and Drug Administration (FDA).

Menopause is not a health problem, it is a natural stage of life. However, the effects it can cause, such as hot flashes, mood changes, and insomnia, can influence the quality of life.

Up to 80% of women report that their quality of life diminishes as a result of menopause symptoms.

Hormone replacement therapy (HRT) can be an effective approach to these symptoms, but it can also increase the risk of developing certain health problems, such as stroke, heart disease, and some cancers.

Some people may wish to use over-the-counter products, such as Amberen Menopause, to relieve menopause symptoms. However, the FDA does not approve dietary supplements.

It is important to speak with a healthcare professional about the benefits and risks of any over-the-counter menopause products before making a purchase. These can interact with other prescription or nonprescription treatments.

This article discusses what Amberen Menopause is, its pros and cons, and its side effects.

Please note that the writer of this article has not tried these products. All information presented is purely research-based and was correct at the time of publication.

Amberen Menopause is an over-the-counter dietary supplement. Its manufacturers claim that it can affect hormone levels in a way that reduces menopause symptoms.

The product does not contain any hormones, herbs, or soy. Its ingredients include a blend of amino acids, minerals, and vitamin E.

Amberen notes that the product is not suitable for people who are pregnant or breastfeeding or have severe high blood pressure, also known as hypertension.

Amberen does not have a Better Business Bureau profile. Its Trustpilot page shows an average customer rating of 1.9 out of 5 stars.

Positive reviews report a decrease in night sweats, mood swings, and insomnia. Some customers also say that their energy levels increased after taking the product.

Negative reviews report that customers had migraine headaches, bloating, and constipation after starting to take the product. Others say that energy levels decreased and nausea and anxiety developed during Amberen Menopause treatment.

Customer reviews on Amberen’s website and the Trustpilot page show the following pros and cons of using this product.


  • It may improve sleep.
  • It may reduce stress.
  • It may reduce night sweats.
  • It may increase energy.


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Amberen Menopause uses a proprietary blend. This means that while the company may list all the ingredients on labeling, it does not disclose the amounts of these ingredients.

The company says that Amberen Menopause contains:

  • ammonium succinate
  • calcium disuccinate
  • magnesium disuccinate
  • zinc difumarate
  • glycine
  • monosodium l-glutamate
  • vitamin E (tocopheryl acetate)

A 2019 review of studies that investigated the effectiveness of the product found that it provides some relief for 16 of the 21 menopause symptoms included in the data. Additionally, the review found that it may reduce anxiety, it significantly raises estradiol levels, and it reduces leptin levels.

However, the four authors of this investigation have all disclosed conflicts of interest. One is a paid consultant for Amberen, and the other three were involved in the original studies being reviewed.

Overall, there is little scientific evidence that Amberen’s ingredients can help relieve menopause symptoms.

For example, a 2018 review notes that, while vitamin E is positively associated with bone mass density, there is little correlation between ingesting vitamin E and having an increase in bone mass during menopause.

Amberen does not list possible side effects on its website. However, reviews on Trustpilot report that customers experienced the following while taking the product:

Anyone who has any adverse effects while taking Amberen Menopause should stop taking it and contact a healthcare professional.

Amberen Menopause is available for purchase online and in stores such as Walgreens, Costco, Target, and CVS.

At the time of publishing, a 30-day supply cost $29.99 on Amberen’s website.

Below, we compare Amberen Menopause with Estroven, which is another dietary supplement for menopause symptoms, and Premarin, an FDA-approved form of HRT.

Estroven contains black cohosh, soy isoflavones, and rhapontic rhubarb extract.

There is little scientific evidence that black cohosh has a significant effect on menopause symptoms. In addition, it is likely unsuitable for anyone with a history of breast cancer, endometrial cancer, thromboembolic disorders, undiagnosed vaginal bleeding, endometriosis, fibroids, or a history of any liver disorder.

If a person develops any symptoms of liver problems, such as abdominal pain, dark urine, or yellowing of the skin or eyes, they should stop taking Estroven and contact a healthcare professional.

There is evidence that rhapontic rhubarb, another ingredient in Estroven, has estrogen-like activity.

Premarin is an estrogen-only form of HRT. Its active ingredients are sodium estrone sulfate and sodium equilin sulfate, which help boost the amounts of estrogen in the body.

Amberen MenopauseEstrovenPremarin
Main ingredientammonium succinate• black cohosh
• soy isoflavones
• rhapontic rhubarb extract
• sodium estrone sulfate
• sodium equilin sulfate
FDA approvalno FDA approvalno FDA approvalFDA approval granted in 1998
Who is it not suitable for?• those who are pregnant
• those who are breastfeeding
• those who have severe hypertension
• those who are pregnant
• those who are breastfeeding
• those with abnormal genital bleeding
• those who have or have a history of breast cancer
• those who have a breast tumor that is dependent on estrogen
• those who have or have a history of deep vein thrombosis and pulmonary embolism
• those who have had a stroke
• those who have liver disease
• those who are pregnant
• those who are allergic to Premarin
Side effects• migraine headaches
• bloating
• constipation
• fatigue
• limb pain
• nausea
• vaginal bleeding
• breast pain
• bloating
• rash
• headache
• breast pain
• stomach cramps and bloating
• fluid retention
• hair loss
• nausea and vomiting
• irregular vaginal bleeding or spotting
• vaginal yeast infection

Amberen Menopause is an over-the-counter dietary supplement that claims to relieve menopause symptoms. However, the only clinical studies that have investigated its effectiveness have conflicts of interest. There is also little evidence that its ingredients are effective.

Before taking any over-the-counter treatment, carefully weigh the pros and cons and discuss these with a pharmacist, doctor, or another healthcare professional.