Some people may need to take antibiotics to help treat boils. Some of the most effective antibiotics include oxacillin, daptomycin, and telavancin.

Boils are a form of bacterial skin infection that presents as inflamed, tender, pus-filled sores.

Minor or small boils often resolve on their own with good hygiene and at-home treatments, such as warm compresses. However, large or complex boils, boils on the face or neck, and chronic boils often require a doctor to drain them. Some people may also need to take antibiotics.

This article discusses what a boil is, which antibiotics may be effective, why it is important to take antibiotics exactly as prescribed, general tips for taking antibiotics, and additional treatments for boils.

antibiotics on a blue surface that can be used for boilsShare on Pinterest
A doctor may prescribe antibiotic treatment for large boils.

A wide range of oral and topical antibiotics may help treat boils. A doctor will determine which medication is most likely to be effective for someone based on several factors, such as:

  • the person’s age
  • additional medical conditions
  • other medications that a person is using or has already tried
  • any allergies
  • the severity of the infection
  • the person’s immune status
  • the risk factors associated with the medication

Staphylococcus (Staph) bacteria cause many boils. Several types of Staph bacteria have adapted to resist certain types of antibiotics, particularly methicillin-based medications.

Several studies have concluded that taking nonmethicillin-based systemic (oral or intravenous) antibiotics after a doctor has incised and drained the boils increases the likelihood of full recovery.

Some of the nonmethicillin-based antibiotics that doctors may use to treat Staph boils include:

  • ceftaroline
  • daptomycin
  • oritavancin
  • vancomycin
  • telavancin
  • dalbavancin

In rare cases, a doctor may take a sample of pus from a boil and send it to a laboratory. There, technicians will analyze it to determine which specific type of bacteria is causing the boil. The doctor may require this information if:

  • standard treatment is not working
  • sepsis (a blood infection) is a possibility
  • someone is allergic to several types of antibiotics or does not respond well to them
  • there is a risk that the bacteria are antibiotic resistant
  • there are multiple boils, or they are recurring
  • the person has a weakened immune system

Knowing which specific type of bacteria is causing boil infections usually makes treatment more effective.

It is extremely important to take antibiotic medications exactly as per the prescription and to complete the whole course, even if the symptoms go away.

Not taking the whole course of prescribed antibiotics increases the risk that the infection will return and that the bacteria causing the infection will become antibiotic-resistant. People with a staph infection should take particular care, as several staph species are already antibiotic-resistant.

Some research suggests that shorter courses of antibiotics may be as effective as longer courses. However, the doctor prescribing the antibiotics will prescribe as much as they feel appropriate. So, it is important to follow their advice.

Adhering to the doctor’s prescription for antibiotics is extremely important. People can also maximize the safety and effectiveness of antibiotics by doing the following:

  • take them exactly as the doctor has prescribed
  • do not skip doses
  • do not save doses for the future
  • do not take antibiotics prescribed for someone else
  • tell a healthcare professional about all current medications
  • report any new or unusual symptoms to a healthcare professional
  • take any questions to a doctor or pharmacist

In many cases, people do not need to take antibiotics for boils. Instead, several at-home remedies may help accelerate the healing process or improve the chances of recovery.

Additional treatment options for boils include:

  • Using a warm compress: Make a warm compress by heating a wet, clean cloth or facecloth and gently applying it to the boil for 10–20 minutes, three to four times a day.
  • Covering boils: Cover boils with sterile gauze or a bandage, especially once they have burst.
  • Washing the hands and body frequently: Wash the hands thoroughly with hot water and soap before and after touching boils. Wash the body daily with a gentle antiseptic or antibacterial cleanser.
  • Avoiding forcing boils open: Never try to squeeze, pierce, or forcibly open a boil, as this can spread the infection and cause it to become more severe.
  • Taking over-the-counter (OTC) pain relievers: Take medications such as paracetamol or ibuprofen to reduce or manage pain associated with boils.

In certain cases, a doctor may also make a small cut to drain boils in their office. They may do this for boils that:

  • are severe
  • are on the face or neck
  • recur
  • do not resolve on their own
  • have merged with other boils, forming a carbuncle

In some cases, a doctor may also prescribe antiseptic creams or ointments that a person can apply to the inside of their nose to help limit staph infection.

OTC topical antibacterials, such as Neosporin, will not help treat boils as they do not penetrate the skin enough.

A doctor may prescribe one of several types of antibiotics that can help treat boils. Typically, the most common and effective antibiotics are not methicillin-based, but a doctor will decide which antibiotics or other treatments are most appropriate.

Some people may be able to manage boils with at-home remedies, and some boils may resolve on their own. In other cases, people may need medical help and require a doctor to drain a boil and prescribe antibiotics.

It is best to talk to a doctor about severe boils, clusters of boils, and boils with accompanying symptoms. People should also talk to a doctor if boils do not fully heal after completing a whole course of antibiotics.