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Diaper rash causes a red, irritating rash that can bother babies and worry caregivers. There are, however, a number of creams that may help to alleviate symptoms.

The warm, moist environment inside a baby’s diaper, coupled with friction from movement and the presence of fungus and bacteria on the skin, can lead to diaper rash.

Diaper rash affects an estimated 50–65% percent of babies. Diaper rash creams can cut down on the contributing factors by creating a barrier between the skin and moisture, as well as reducing friction.

Keep reading to learn more about some of the best diaper rash creams available for purchase.

Boudreaux’s Butt Paste has more than 2,700 parent supported reviews on Amazon. The maximum strength version contains 40% zinc oxide, castor seed oil, mineral oil, and petrolatum. It is also free of talc, preservatives, dyes, and parabens.

The paste is very thick and is best suited for treating moderate to highly irritated diaper rash.

Purchase it here.

Diaper rash creams are thick and frosting-like, which can be difficult to apply on an always-moving baby. This stick balm from GroVia is an alternative to more messy pastes.

The balm is best for minor skin irritation and as a skin protectant. It has natural skin softening ingredients, such as grape seed, lavender, jojoba seed, and shea butter.

Something to remember is that if someone has more than one baby at home, each will need their own stick. This cuts back on sharing unwanted visitors, such as fungi.

Purchase it here.

The Honest Company’s Diaper Rash Cream is a cream that product-testing company NSF International certified for its organic ingredients.

The cream is free from dyes, synthetic fragrances, silicons, petrolatum, mineral oil, and lanolin.

It contains 14% nonnano zinc oxide. This formulation will sit on top of the skin without penetrating it.

It also contains skin softening oils that repel moisture, such as sunflower seed, coconut, and olive oil.

The cream is for moderately irritated diaper rash. People may need something stronger if they apply the cream for 7 days, and the diaper rash does not improve.

Purchase it here.

This diaper rash spray from Boogie Bottoms is a touchless alternative to traditional creams and has more than 2,500 positive Amazon reviews.

The active ingredient is 25% zinc oxide, and it does not have fragrances, dyes, and parabens. Parents review it highly for its easy-to-use spray that does not require rubbing.

The spray has a spray lock to help keep curious babies from accidentally spraying. Users must make sure to engage the lock between diaper changing sessions.

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This A+D ointment has more than 3,200 ratings, with five out of five stars on Amazon.

The ointment contains 15.5% lanolin and 53.4% petrolatum, which helps prevent skin chafing while also repelling water. The formulation is free of dyes, parabens, and phthalates.

The formula is protective enough for parents to use it on their own dry skin, such as cracked lips and chafed knees or elbows.

The ingredients can be staining to cloth diapers. Parents reviewing the product suggested using a protective liner between the cloth diaper and ointment when applying.

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Aquaphor’s Healing Ointment is safe for baby’s skin and treating and preventing diaper rash while also addressing other areas of skin irritation. Examples include teething rashes, eczema areas, and chafed skin.

The clear ointment contains petrolatum, mineral oil, glycerin, and lanolin.

A consideration for this product, as with many others, is how difficult it may be to apply.

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A well-known name in diaper rash fighting, Desitin cream contains 40% zinc oxide plus petrolatum, lanolin, talc, and cod liver oil.

The formula gives maximum strength treatment and protection for diaper rash, particularly overnight.

According to the manufacturer’s website, an estimated 90% of babies with diaper rash had noticeable relief within 12 hours of application.

The cream is frosting-like in consistency, so people need to apply it carefully and be prepared to wash their hands a few times to get all the cream off.

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This plant-based diaper rash cream contains skin soothing ingredients, including noncolloidal oatmeal, shea butter, and organic calendula.

The formula is nonsticky with a smooth texture that is diaper friendly. It also contains 25% nonnano zinc oxide. The formulation is suitable for babies with sensitive skin.

The product does have a natural scent from its components. While many parent reviewers reported loving the scent, it may not be for everyone.

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Red, itchy eczema plagues many babies, and this baby healing ointment from CeraVe can treat both eczema and diaper rash woes.

The National Eczema Association awarded the ointment its Seal of Acceptance.

It does not contain lanolin, which can irritate some babies’ skin, or fragrances. The cream does contain skin softening ceramides that help to create a barrier between moisture and the skin.

This multi-use cream can help treat and prevent milder cases of diaper rash, but may not help those with moderate diaper rashes.

Purchase it here.

Diaper rash creams are useful for treating and preventing diaper rash, and a number of products are available.

Regular skin cleansing with gentle soap and water, changing diapers frequently and allowing a baby to spend some time without a diaper on may also help treat the condition.

With regular applications to clean skin, people can help their baby overcome diaper rash.

If the diaper rash worsens or does not improve with treatment, it may be time to call the child’s pediatrician.