Cannabidiol (CBD) is an increasingly popular ingredient for people seeking alternative remedies for various conditions, including chronic pain. CBD comes in the form of oral sprays, as well as edibles and topical products.
Cannabis plants contain compounds called cannabinoids. The two best-known cannabinoids are tetrahydrocannabinol (THC) and CBD.
THC can lead to psychological effects and the “high” that people frequently associate with cannabis. CBD, however, does not produce the same psychoactive effects. It might, on the other hand, have numerous potential health benefits.
Various forms of CBD exist, including oils, gummies, topicals, and oral sprays. However, it is important to note that availability
Keep reading to learn more about the effects and potential benefits of CBD oral sprays. This article also covers how this form of CBD compares with others that are available.
CBD products are available in many forms, including oral sprays.
Sprays involve a tincture of CBD extract and ethanol alcohol. The alcohol helps extract the cannabinoids. An oral spray dispenses directly into the mouth, either under the tongue or inside the cheek.
Although the research into CBD’s use as a remedy for various conditions is ongoing, studies that support CBD’s purported benefits are
The following conditions may benefit from CBD use.
There are anecdotal reports of people who use CBD experiencing anxiety-reducing effects. CBD
However, existing studies into the effects of CBD on anxiety involve only small groups of participants. Further research may help clarify the potential link between the two.
Chemotherapy side effects
People undergoing chemotherapy for cancer may experience nausea and vomiting. Doctors usually prescribe antiemetics to counteract these unpleasant side effects.
A 2018 study found that CBD limited a surge of serotonin levels in the interoceptive insular cortex (IIC) of rats that received injections of a nausea-inducing chemical compound.
The IIC region of the human brain is responsible for nausea. Therefore, the findings suggest that it may be possible for scientists to develop a CBD-based antinausea treatment for people receiving chemotherapy treatment.
One 2019 review also suggests that cannabinoids may help prevent other adverse effects associated with chemotherapy, including poor appetite and pain. That said, the evidence in this area is weak.
There is evidence to suggest that cannabinoids may help with pain relief, but few studies exist on CBD specifically.
A 2018 review took into account 48 studies on using cannabinoids and cannabis for the relief of chronic non-cancer-related pain.
The authors suggest that there is moderate evidence pointing to the pain-relieving effects of cannabinoids compared with a placebo. However, people using cannabinoids were also more likely to experience adverse effects than those taking the placebo.
A more recent study analyzed the evidence surrounding the benefits and harms of medical cannabinoids in the treatment of chronic non-cancer-related pain. At 2 weeks, there was “moderate evidence” to support the use of cannabinoids in treating this type of pain.
Although current evidence does not fully support the use of CBD for relief from chronic pain, new research and clinical trials are on the horizon. For example, the
However, there has been little research into the benefits of CBD for milder, more common forms of epilepsy.
Limited evidence suggests that CBD may help people with substance abuse disorder by curbing compulsive behaviors.
One study from 2019 found that CBD may help people with heroin use disorder by reducing cravings and anxiety.
Although this preliminary research is encouraging, more studies are necessary to establish conclusive evidence.
Although CBD oral sprays need longer to take effect than smoking or vaping, they are faster-acting than edible forms of CBD.
Oral sprays can have an unpleasant aftertaste, but some have flavorings to make them more palatable.
When using CBD oral spray, it can be challenging to determine the correct dose. As with any form of cannabinoid, it is best to start small to prevent unpleasant side effects.
Oral sprays such as Epidiolex are standardized to meet formulation and dosage regulations. With these, a person will know exactly how much they are getting with each spray.
However, the effects of oral sprays may last longer and be stronger than with vaping or smoking.
Researchers still have a limited understanding of how CBD affects the human body.
Risks and side effects are
Some potential adverse effects of CBD include:
- liver damage
- drug interactions
- an increased risk of sedation (when a person combines CBD with alcohol or certain medications)
- decreased appetite
- altered alertness
Researchers have yet to answer certain questions about CBD, including the following:
- What are the effects of prolonged exposure?
- Can high doses cause an increase in adverse effects?
- Does CBD hinder or alter brain development?
- Are certain people at higher risk of experiencing adverse effects?
- Is it safe for animals to consume CBD?
Although the FDA have only approved a single CBD-containing medication for severe forms of epilepsy, there are many products that contain CBD.
Therefore, people should use products containing CBD with caution and never use them in place of conventional medical treatments.