Cervical cancer can impact people before and during pregnancy. Early screening and comprehensive care from a multidisciplinary medical team can help many people with cervical cancer experience a healthy pregnancy and delivery.
Cervical cancer occurs when cancerous cells grow in the cervix, a part of the lower uterus. According to
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This article looks at the link between cervical cancer and pregnancy, treatment options for pregnant people with cervical cancer, the symptoms of cervical cancer, and more.
Doctors typically identify cervical cancer in pregnant people at an early stage. Early detection of cervical cancer increases the chances of successful treatment.
How cervical cancer affects a person’s pregnancy will depend on several factors, such as:
- the type of cervical cancer
- the size of the tumor
- whether the cancer has spread
- how many weeks pregnant a person is
- the wishes of the individual regarding treatment and continuing their pregnancy
Method of delivery
If a pregnant person receives a diagnosis of cervical cancer, their method of delivery may change. For instance, doctors typically recommend a cesarean section for people with the condition. This is because vaginal delivery can carry
Doctors may recommend surgery or chemotherapy to treat a person’s cancer, which they may carry out during or after pregnancy, depending on the individual case. A person will work with a doctor to determine which chemotherapy drugs will be safe for them to use, as the timing of chemotherapy treatment and the type of drug
Every case of cervical cancer during pregnancy is different and will involve a multidisciplinary team of health professionals.
Doctors a person might work with
- gynecological oncologists, specialists in cancers of the female reproductive system
- medical oncologists, specialists in cancer drug treatments
- perinatologists, specialists in the care of pregnant people and fetuses
- neonatologists, specialists in the care of newborn babies
Working with a team of medical professionals will help a person understand how the condition might affect their pregnancy.
After a cervical cancer diagnosis, people may worry about their ability to have children in the future. The
- their baseline fertility
- their age
- the type of cancer treatments they have
- the treatment dosage
- the duration of treatment
- the time since a person’s last treatment
- an individual’s overall health
A person with early stage cancer
- conization, which involves removing a piece of the cervix
- simple trachelectomy, which involves removing a larger portion of the cervix
- radical trachelectomy, which means removing the cervix and nearby tissue
Some people may not learn that they have cervical cancer until they are pregnant. Regular pregnancy exams can detect the presence of cervical cancer.
In many cases, infertility only becomes a risk after
Fertility rates vary between people and over time. Anyone trying to become pregnant after a cervical cancer diagnosis should consult with a medical professional.
Choosing a treatment course for cancer during pregnancy is a complex and highly personal decision that will involve a multidisciplinary medical team. Treatment plans can vary according to the pregnancy trimester.
It is important to note that doctors
Below is an explanation of the treatment options available during each trimester of pregnancy.
According to Cancer Research UK, doctors will not treat a person with chemotherapy in the first trimester as it can cause damage to the growing fetus or pregnancy loss.
The organization also notes that it is sometimes possible for a person to have small tumors removed with a cone biopsy or trachelectomy. However, it warns that a trachelectomy comes with a risk of bleeding and miscarriage.
If a person is less than 3 months pregnant, doctors may recommend getting treatment immediately. At this early stage, a person may need to choose to end their pregnancy. Their medical team will support them through this decision.
If a person chooses to continue with their pregnancy, they will start treatment once they are 3 months pregnant, in the second trimester.
If a person receives a cervical cancer diagnosis during the second trimester, doctors may suggest they continue with the pregnancy and have an early cesarean section delivery.
A person may have a hysterectomy at the same time as their cesarean section. They can then begin chemotherapy or radiation treatment.
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In the third trimester, a person may continue any chemotherapy treatments that their medical team considers safe.
A doctor may carry out an early delivery through a cesarean section. Doctors will aim to deliver the baby after 37 weeks of pregnancy. However, they will consider the health of the pregnant individual and the fetus carefully when deciding when delivery would be safest.
After delivery, a person can begin or continue their chosen treatment plan for cervical cancer.
An older study from
Doctors generally consider chemotherapy relatively safe in the second and third trimesters. That said, certain cancer drugs, such as trastuzumab (Herceptin), are unsafe during pregnancy because they can negatively affect a fetus’s kidneys and lungs.
In rare cases, major cervical surgery may lead to pregnancy loss.
More research is needed to determine how cancer treatments affect fetuses during pregnancy and after birth. People experiencing cervical cancer during pregnancy should talk with a doctor about their options and the risks of cancer treatments for their and their baby’s health.
People may experience no symptoms during the early stages of cervical cancer. As the condition progresses, symptoms can become more pronounced. These may include:
- abnormal vaginal bleeding or discharge
- bleeding after sexual intercourse
- pain in the pelvic region
- pain during sexual intercourse
A few of these symptoms may overlap with early signs of pregnancy. People in the early stages of pregnancy may experience:
Changes in vaginal discharge can indicate a variety of conditions. People experiencing such changes should contact a doctor to determine the cause.
Doctors typically divide cervical cancer into
- Stage 1: During this stage, cancer occurs in the cervix and uterus.
- Stage 2: Cancer has spread to other areas in the pelvic area, such as the vagina.
- Stage 3: At this stage, cervical cancer may include tumors in the lower vagina or pelvic wall. It may affect kidney function or nearby lymph nodes.
- Stage 4: The tumor has spread to parts of the body even further away.
Early stage cancers are generally manageable during pregnancy. Doctors may recommend immediate, deferred, or no treatment depending on the cancer stage, pregnancy trimester, and the individual’s goals for care.
People with more advanced cervical cancer may need surgery during pregnancy.
If a person wishes to continue their pregnancy and needs surgery to treat their cancer, they should work with a doctor to consider the risks of cancer progression alongside the health and development of the fetus.
Cervical cancer during pregnancy
Researchers generally consider chemotherapy safe in the second and third trimesters, although there is a limited number of studies in this area.
People with cervical cancer during pregnancy should discuss the risks and complications related to treatment and cancer progression with a medical professional.
Cervical cancer is a serious condition, but it is relatively rare in pregnancy. Doctors typically identify cervical cancer during pregnancy in the early stages of the disease. This improves the likelihood of a person having a healthy pregnancy and delivery.
Cervical cancer treatment varies according to the pregnancy trimester, the cancer stage, the healthcare resources available to a person, and their goals for treatment.
Individuals with cervical cancer during pregnancy should regularly visit a medical professional and work closely with a multidisciplinary team to choose a treatment plan that is right for them.