Acyclovir is a generic drug that’s prescribed for certain viral infections. It’s available as the brand-name drugs Sitavig and Zovirax. The cost of acyclovir with and without insurance can depend on several factors.

As with all medications, the cost of acyclovir can vary. Factors that may affect the price you’ll pay include your treatment plan, your insurance coverage, and the pharmacy you use.

To find out what the cost of acyclovir will be for you, talk with your doctor, pharmacist, or insurance provider. Or look below in the next section to learn how much you can save by using an Optum Perks coupon.

To save money on your acyclovir prescription, explore these Optum Perks coupons.

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Acyclovir is a generic drug, which means it’s an exact copy of the active ingredient in a brand-name medication. A generic drug is considered to be as safe and effective as the original drug. And generics tend to cost less than brand-name drugs.

Acyclovir is available as the brand-name drugs Sitavig and Zovirax. Sitavig comes as a buccal tablet and is approved to treat cold sores (herpes labialis). If your doctor has prescribed acyclovir and you’re interested in using one of these drugs instead, talk with your doctor. They may have a preference for one version or the other. You’ll also need to check with your insurance provider, as it may only cover one or the other.

To find out how the cost of these brand-name drugs compares with the cost of acyclovir, talk with your doctor, pharmacist, or insurance provider.

If you take acyclovir long term, you may be able to lower its cost in the following ways.

Getting a 3-month supply

You may be able to get a 90-day supply of acyclovir. If approved by your insurance company, getting a 90-day supply of the drug could reduce your number of trips to the pharmacy and help lower the cost. If you’re interested in this option, check with your doctor, pharmacist, or insurance provider.

Using a mail-order pharmacy

Acyclovir may be available through a mail-order pharmacy. Using this type of service may help lower the drug’s cost and allow you to receive your medication without leaving home. Some Medicare plans may help cover the cost of mail-order medications. You may also be able to get a 90-day supply of the drug via mail order.

If you don’t have health insurance, talk with your doctor or pharmacist. They may be able to suggest online pharmacy options that could work for you.

If you need financial support to pay for acyclovir, consider looking into websites that offer cost resources and information. Two such organizations are:

These sites can provide details about drug assistance programs, ways to make the most of your insurance coverage, and links to savings cards and other services.

Here are answers to some frequently asked questions about drug cost and acyclovir.

How much does acyclovir cost with insurance vs. without it?

What you pay for acyclovir if you have insurance compared to what you’d pay without it depends on several factors.

Factors that could affect what you pay for this drug without insurance include:

  • the quantity you’re prescribed (such as a 90-day or 30-day supply)
  • whether you apply and qualify for any available savings programs
  • your dosage and treatment plan
  • the pharmacy you use
  • the form of the drug you’re prescribed (such as the oral capsule or topical cream)

These same factors may affect your price for acyclovir if you have insurance. But the price you pay with insurance will also depend on:

  • your specific plan benefits
  • any prior authorization requirements you have for drug coverage

To learn more about what you’d pay for acyclovir with or without insurance, talk with your doctor, pharmacist, or insurance provider (if you have one).

You can also visit Optum Perks* for price estimates for this drug when using coupons from their site. However, Optum Perks coupons cannot be used with insurance benefits or copays.

* Optum Perks is a sister site of Medical News Today.

Is acyclovir covered by Medicare?

It may be. You can call your Medicare plan provider to learn whether your particular plan covers the cost of this drug. There are many types of Medicare plans, so your coverage and what you pay for prescriptions will be based on your particular plan’s benefits.

You may also need to obtain prior authorization before your plan will cover the cost of this medication.

Your doctor may have information about your cost for acyclovir if you have Medicare.

Below is information you may want to consider if you have insurance and receive acyclovir.

If you have insurance, your insurance company may require prior authorization before it covers acyclovir. This means the company and your doctor will discuss acyclovir in regard to your treatment. The insurance company will then determine whether the medication is covered. If a drug requires prior authorization but you start treatment without the prior approval, you could pay the full cost of the medication. You can ask your insurance company whether acyclovir requires prior authorization.

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.