Ajovy (fremanezumab-vfrm) is a brand-name subcutaneous injection prescribed for migraine prevention in adults. Ajovy has no known interactions with alcohol, drugs, or supplements. However, the drug has certain health-related interactions.

An interaction occurs when one substance causes another substance to have a different effect than expected.

To learn more about Ajovy’s interactions, keep reading. For additional information about Ajovy, including details about its uses, see this article.

The manufacturer of Ajovy did not study drug interactions in clinical trials. However, it’s possible for interactions to be recognized in the future. For example, people who have used Ajovy since it became available might report a suspected interaction.

Before you start treatment with Ajovy, tell your doctor and pharmacist which prescription, over-the-counter, and other medications you take. By sharing this information with them, you may help prevent possible interactions. (To learn whether Ajovy interacts with supplements, herbs, or vitamins, see the “Ajovy and other interactions” section below.)

If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.

Sometimes, factors or conditions could prevent your doctor from prescribing Ajovy due to the risk of harm. These are known as contraindications. The Ajovy contraindications include:

Having had an allergic reaction to Ajovy or any of its ingredients

If you have had an allergic reaction to Ajovy or any of its ingredients, your doctor will likely not prescribe Ajovy. Using the drug could cause another allergic reaction. You can ask them about other treatments that may be better choices for you.

Note: Before you start treatment with Ajovy, it’s important to tell your doctor if this contraindication applies to you. They can determine whether to prescribe Ajovy.

There are no known interactions between Ajovy and alcohol. However, your doctor may advise you to avoid or limit alcohol consumption during Ajovy treatment.

This is because drinking alcohol can trigger a migraine for some people. (Doctors prescribe Ajovy for migraine prevention.)

If you have questions about limiting or avoiding alcohol during Ajovy treatment, talk with your doctor.

Ajovy may interact with other substances, such as supplements, foods, vaccines, or even lab tests. You’ll find details below. Keep in mind that the following information does not include all possible interactions with Ajovy.

Ajovy and supplements

It’s possible for drugs to interact with supplements such as vitamins and herbs.

Ajovy and herbs

There are no specific reports of herbs interacting with Ajovy. However, that doesn’t mean herbal interactions won’t occur or be recognized in the future. Because of this, it’s important to check with your doctor or pharmacist before taking any of these products during Ajovy treatment.

Ajovy and vitamins

There are no specific reports of vitamins interacting with Ajovy. However, that doesn’t mean vitamin interactions won’t occur or be recognized in the future. Because of this, you should talk with your doctor or pharmacist before taking any vitamin product with Ajovy.

Ajovy and food

There are no specific reports of foods interacting with Ajovy. If you’d like to learn more about eating certain foods during treatment with Ajovy, talk with your doctor.

Ajovy and vaccines

There are no known interactions between Ajovy and vaccines. Talk with your doctor or pharmacist to see whether you’re due for any vaccines.

Ajovy and lab tests

Ajovy is not known to interact with any lab tests. If you have concerns about this medication interacting with lab tests, talk with your doctor.

AJOVY AND CANNABIS OR CBD

Cannabis (often called marijuana) and cannabis products, such as cannabidiol (CBD), have not been specifically reported to interact with Ajovy. However, as with any drug or supplement, talk with your doctor before using cannabis in combination with Ajovy. The impact of cannabis may affect how well you stick to your Ajovy treatment plan.

Note: Cannabis is illegal at a federal level but is legal in many states to varying degrees.

Certain medical conditions and other factors may increase the risk of interactions with Ajovy. Before you receive this drug, be sure to talk with your doctor about your health history. Ajovy may not be the right treatment option if you have certain medical conditions or other factors affecting your health.

Health conditions or factors that might interact with Ajovy include:

  • Allergic reaction: If you’ve had an allergic reaction to Ajovy or any of its ingredients, your doctor will likely not prescribe Ajovy. Using the drug could cause another allergic reaction. You can ask them about other treatments that may be better choices for you.
  • Breastfeeding: It is unknown whether it’s safe to use Ajovy while breastfeeding. There isn’t enough information to determine whether the drug passes into breast milk or what effects Ajovy may have on a child who is breastfed. If you’re breastfeeding or planning to, talk with your doctor before using Ajovy. They can talk with you about treatment options and ways to feed your child.
  • Pregnancy: There haven’t been enough clinical trials to determine whether Ajovy is safe to use while pregnant. If you’re pregnant or planning to become pregnant, tell your doctor before starting Ajovy. They can advise you on the right treatment plan for you.

Note: If you’re prescribed Ajovy during pregnancy, consider enrolling in a pregnancy registry for migraine drugs. This registry keeps track of issues that may occur when Ajovy is used during pregnancy. To learn more, visit the registry website. You can also call 833-927-2605 or talk with your doctor.

You can take certain steps to help prevent interactions with Ajovy. Your doctor and pharmacist are key resources, so reach out to them before starting treatment. For example, you should plan to do the following:

  • Let them know if you drink alcohol or use cannabis.
  • Tell them about any other medications you take, as well as any supplements, herbs, and vitamins.
  • Create a medication list, which your doctor and pharmacist can help you fill out.

It’s also important to read the Ajovy label and other paperwork that may come with the drug. The label may have colored stickers that mention an interaction. And the paperwork, sometimes called the medication guide or patient package insert, may contain details about interactions.

If Ajovy doesn’t come with paperwork, you can ask your pharmacist to print a copy. If you need help reading or understanding this information, ask your doctor or pharmacist.

You can also help prevent interactions with Ajovy by using it exactly as your doctor prescribes.

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.