Breztri Aerosphere (budesonide/glycopyrrolate/formoterol fumarate) is a brand-name prescription medication. The Food and Drug Administration (FDA) has approved it for long-term treatment of chronic obstructive pulmonary disease (COPD) in adults.

For more information about Breztri Aerosphere’s uses, refer to this article.

Drug details

Here are some details about Breztri Aerosphere:

  • Drug form: metered-dose inhaler
  • Generic: not available

Read on to learn about Breztri Aerosphere and cost, as well as how to save money on prescriptions.

As with all medications, the cost of Breztri Aerosphere can vary. Factors that may affect the price you’ll pay include:

  • your treatment plan
  • your insurance coverage
  • the pharmacy you use
  • whether there’s a savings program for Breztri Aerosphere that’s right for you (see the “Financial and insurance assistance” section below)

To find out what the cost of Breztri Aerosphere will be for you, talk with your doctor, pharmacist, or insurance provider.

Note: If you have insurance, your insurance company may require prior authorization before it covers Breztri Aerosphere. This means the company and your doctor will discuss Breztri Aerosphere in regard to your treatment. The insurance company will then determine whether the medication is covered. If a drug requires prior authorization, but you start treatment without the prior approval, you could pay the full cost of the medication. You can ask your insurance company whether Breztri Aerosphere requires prior authorization.

Here are answers to some frequently asked questions about drug cost and Breztri Aerosphere.

What is the cost of Breztri Aerosphere with insurance and without insurance?

The cost of Breztri Aerosphere can vary based on your insurance plan (if you have one) and other factors. These factors include if you’re eligible for cost savings programs, your treatment plan, and the pharmacy you use.

If you have insurance, you can contact your plan by calling the phone number on the back of your insurance card. They can tell you how much you’ll pay based on your benefits. They can also tell you if there is a preferred or in-network pharmacy for their participants.

If you don’t have insurance, talk with your pharmacist. Some pharmacies offer discounts to those without coverage. Your pharmacist may also be able to suggest other savings programs available for Breztri Aerosphere.

How much does Breztri Aerosphere cost with Medicare?

The cost of Breztri Aerosphere with Medicare depends on your particular Medicare plan. There are many different plans, and costs can vary based on your prescription drug benefits.

Your plan may also have prior authorization requirements you must meet, which can affect the cost of the drug.

You may want to contact your Medicare provider to find out the cost of Breztri Aerosphere for you.

You can also learn more about Medicare savings programs in the “Ways to reduce long-term drug costs” and “Financial and insurance assistance” sections below. These sections give you helpful tips and information about ways to save money on your prescription.

Is there a difference in the cost of Breztri Aerosphere and Trelegy Ellipta?

Maybe. The cost of Breztri Aerosphere compared with Trelegy Ellipta can vary based on whether you have insurance coverage, your plan benefits, and your treatment plan.

If you don’t have insurance, the pharmacy you use and eligibility for cost savings can affect your cost of these two medications.

To find out the cost comparisons between Breztri Aerosphere and Trelegy Ellipta, ask your doctor or pharmacist for details. You can also check with your insurance provider (if you have one) on plan benefits and which drug is covered by your plan.

Breztri Aerosphere is only available as a brand-name drug. It doesn’t come in a generic version. A generic drug is an exact copy of the active drug in a brand-name medication.

Generics tend to cost less than brand-name drugs.

The active ingredient in Breztri Aerosphere is budesonide/glycopyrrolate/formoterol fumarate.


Brand-name drugs can be expensive because of the research needed to test their safety and effectiveness. The manufacturer of a brand-name drug can sell it for up to 20 years. When the brand-name drug’s patent expires, multiple manufacturers can create generic versions. This marketplace competition may lead to lower costs for generics. Also, because generics contain the same active ingredients as brand-name drugs, they don’t require the same costly testing.

If you take Breztri Aerosphere long term, you may be able to lower its cost in the following ways.

Getting a 3-month supply

You may be able to get a 90-day supply of Breztri Aerosphere. If approved by your insurance company, getting a 90-day supply of the drug could reduce your number of trips to the pharmacy and help lower the cost. If you’re interested in this option, check with your doctor, pharmacist, or insurance provider.

Using a mail-order pharmacy

Breztri Aerosphere may be available through a mail-order pharmacy. Using this type of service may help lower the drug’s cost and allow you to receive your medication without leaving home. Some Medicare plans may help cover the cost of mail-order medications. You may also be able to get a 90-day supply of the drug via mail order.

If you don’t have health insurance, talk with your doctor or pharmacist. They may be able to suggest online pharmacy options that could work for you.

If you need financial support to pay for Breztri Aerosphere, or if you need help understanding your insurance coverage, help is available. For example:

  • A program called Breztri Zero Pay is available for Breztri Aerosphere for those who have private insurance coverage to lower the cost of Breztri. For more information and to find out if you’re eligible for support, call 833-458-0440 or visit the program website.
  • Some websites provide details about drug assistance programs, ways to make the most of your insurance coverage, and links to savings cards and other services. Two such websites are:

To learn more about saving money on prescriptions with or without insurance, check out this article.

Now that you’ve learned about cost and Breztri Aerosphere, you may still have some questions. Talk with your doctor or pharmacist, who can provide personalized guidance about cost issues related to Breztri Aerosphere. But if you have health insurance, you’ll need to talk with your insurance provider to learn the actual cost you would pay for Breztri Aerosphere.

Here are some other resources you may find helpful:

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.