Bryhali (halobetasol) is a brand-name drug prescribed to treat plaque psoriasis in adults. Bryhali comes as a topical lotion that’s applied to your skin once per day.

Bryhali belongs to a drug class called corticosteroids. It’s not available in a generic version.

Keep reading for specific information about the dosage of Bryhali, including its strength and how to use the medication. For a comprehensive look at Bryhali, see this article.

Note: This article describes the typical dosage of Bryhali provided by the drug’s manufacturer. When taking Bryhali, always follow the dosage prescribed by your doctor.

Below is information about Bryhali’s recommended dosage.

Bryhali form

Bryhali comes as a topical lotion that you apply to your skin.

Bryhali strength

Bryhali comes in one strength of 0.01%. This means that each gram (g) of lotion contains 0.1 milligrams (mg) of halobetasol.

Bryhali comes in tubes of 60 g and 100 g.

Typical dosage

The following information describes the dosage that’s commonly prescribed or recommended. However, be sure to follow the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs.

Dosage for plaque psoriasis

The typical Bryhali dosage for plaque psoriasis is a thin layer of lotion applied to the affected area once per day. For details, see just below, “How to use Bryhali.”

For more information about your specific dosage, talk with your doctor.

Length of treatment

Bryhali is meant to be a short-term treatment for plaque psoriasis. You’ll typically use Bryhali until your condition eases, but for no longer than 8 weeks.

Talk with your doctor if you have questions about how long you can expect to use Bryhali.

Bryhali comes as a lotion that you apply to the affected area(s) of your skin.

Always follow your doctor’s instructions for applying Bryhali. In general, this means using just enough lotion to make a thin layer over the psoriasis plaque. Then, you’ll gently massage the product on the affected area.

You should wash your hands after applying Bryhali (unless you’re treating your hands). Avoid putting Bryhali on your face, armpits, or groin. Unless your doctor instructs you to, you should not use a bandage or another dressing on the area where you applied Bryhali.

You should not use more than 50 g of Bryhali lotion per week. (Bryhali comes in tubes of 60 g and 100 g.)

If you have questions about how to use Bryhali, talk with your doctor or pharmacist.


Some pharmacies offer labels with large print, braille, or a code you scan with a smartphone to convert text to speech. If your local pharmacy doesn’t have these options, your doctor or pharmacist might be able to recommend a pharmacy that does.

If you miss a dose of Bryhali, apply it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and apply your next scheduled dose. Do not use extra Bryhali to make up for the missed dose. Also, you shouldn’t apply Bryhali more than once per day.

To help make sure that you don’t miss a dose, try using a medication reminder. This can include setting an alarm or putting a note where you’ll see it, such as on your bathroom mirror or bedside table. You could also download a reminder app on your phone.

It’s important that you do not use more Bryhali than your doctor prescribes. For some medications, using more than the recommended amount may lead to harmful effects or overdose.

If you use more than the recommended amount of Bryhali

Call your doctor right away if you believe you’ve used too much Bryhali. Another option is to call America’s Poison Centers at 800-222-1222 or use its online tool. If you have severe symptoms, immediately call 911 or your local emergency number, or go to the nearest emergency room.

Below are some frequently asked questions about Bryhali and dosage.

Is the dosage of Bryhali similar to the dosage of Cimzia?

No, the forms and how often you take each drug are different. Bryhali comes as a lotion that’s applied to your skin once per day. Cimzia comes in forms for subcutaneous injection. It’s typically given once every 2 weeks to treat plaque psoriasis.

The amount per dose of each drug differs because they have different active ingredients. (Cimzia’s active ingredient is certolizumab pegol.) Your doctor will prescribe the drug and the dosage that’s right for you.

To learn more about how these drugs compare, talk with your doctor.

How long does it take for Bryhali to start working?

Bryhali starts to work right after you apply your first dose. Because of how the drug works, you likely won’t feel the drug working. It may take up to 2 weeks to see an improvement in your plaque psoriasis. If you don’t see improvement, talk with your doctor. They’ll help determine whether the drug is working to treat your condition.

Note that Bryhali is a short-term treatment. It should not be used for longer than 8 weeks. Talk with your doctor if you have questions about what to expect with Bryhali treatment.

The dosage in this article is the typical dosage provided by the drug’s manufacturer. If your doctor recommends Bryhali for you, they’ll prescribe the dosage that’s right for you. Always follow the dosage that your doctor prescribes.

As with any drug, never change your dosage of Bryhali without your doctor’s recommendation. If you have questions about the dosage of Bryhali that’s best for you, talk with your doctor.

Besides learning about dosage, you may want other information about Bryhali. These additional articles might be helpful:

  • More about Bryhali: For information about other aspects of Bryhali, refer to this article.
  • Details about plaque psoriasis: For details about your condition, see our psoriasis hub.

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.