Buspirone oral tablet is a generic prescription medication that’s used to treat anxiety disorders, such as generalized anxiety disorder, in adults. Anxiety is a condition that causes you to feel symptoms such as stress, apprehension, and nervousness.
Buspirone is not currently available as any brand-name drugs.
Buspirone belongs to a classification of drugs called anxiolytics. These drugs work to decrease symptoms of anxiety.
Buspirone comes as an oral tablet (a tablet taken by mouth) that’s typically taken twice per day. The tablets come in several strengths: 5 milligrams (mg), 7.5 mg, 10 mg, 15 mg, and 30 mg.
Buspirone is not currently available in any brand-name forms. Buspar was the brand-name form of buspirone, but it’s no longer available.
For information about the effectiveness of buspirone, see the “Buspirone uses” section below.
Buspirone is a generic drug. A generic drug is an exact copy of the active drug in a brand-name medication. Buspar is the brand-name medication that buspirone is based on. (However, Buspar is no longer available.)
A generic is considered to be as safe and effective as the original drug. Generics tend to cost less than brand-name drugs.
To learn more about how generics compare with brand-name drugs, see this article.
Buspirone oral tablets can cause mild or serious side effects. The following lists contain some of the key side effects that may occur while taking buspirone. These lists do not include all possible side effects.
For more information about the possible side effects of buspirone, talk with your doctor or pharmacist. They can give you tips on how to manage any side effects that may be concerning or bothersome.
Note: The Food and Drug Administration (FDA) tracks side effects of drugs it has approved. If you would like to notify the FDA about a side effect you’ve had with buspirone, you can do so through MedWatch.
Mild side effects
Mild side effects* of buspirone can include:
- feeling dizzy or lightheaded
- excitement or restlessness
- insomnia (trouble sleeping)
You may experience more side effects in the first week that you take buspirone. However, most of these side effects may go away within a few days or a couple of weeks. But if they become more severe or don’t go away, talk with your doctor or pharmacist.
* This is a partial list of mild side effects from buspirone oral tablet. To learn about other mild side effects, talk with your doctor or pharmacist, or view buspirone oral tablet’s prescribing information.
† To learn more about this side effect, see “Side effect details” below.
Serious side effects
Serious side effects from buspirone aren’t common, but they can occur. Call your doctor right away if you have serious side effects. Call 911 or your local emergency number if your symptoms feel life threatening or if you think you’re having a medical emergency.
Serious side effects and their symptoms can include:
- Serotonin syndrome. Symptoms can include:
- hallucinations (seeing or hearing things that aren’t really there)
- Allergic reaction.*
* For more information about this side effect, see “Side effect details” below.
Side effect details
Here are some details on certain side effects buspirone may cause.
In rare cases, anger can be a side effect of buspirone oral tablets. This was not a common side effect in studies, but some people taking the drug did develop anger or even hostility while using buspirone. To find out how often this side effect occurred in clinical studies, see the drug’s prescribing information.
Symptoms of anger may include:
- increased heart rate
- tense muscles
- clenching your jaw or grinding your teeth
- feeling anxious, nervous, or unable to relax
If you experience any symptoms of anger, be sure to tell your doctor.
If you have a history of anger or if you experience unexplained anger while taking buspirone, tell your doctor. They may want to monitor you more closely during your treatment, or they may recommend a different medication to treat your anxiety.
As with most drugs, some people can have an allergic reaction after taking buspirone.
Symptoms of a mild allergic reaction can include:
- skin rash
A more severe allergic reaction is rare but possible. Symptoms of a severe allergic reaction can include:
- swelling under your skin, typically in your eyelids, lips, hands, or feet
- swelling of your tongue, mouth, or throat
- trouble breathing
Call your doctor right away if you have an allergic reaction to buspirone, as the reaction could become severe. Call 911 or your local emergency number if your symptoms feel life threatening or if you think you’re having a medical emergency.
The dosage for buspirone oral tablets that your doctor prescribes will depend on several factors. These include:
- the type and severity of the condition you’re using buspirone to treat
- other medical conditions you may have
- other medications that you are taking
Typically, your doctor will start you on a low dosage. Then they’ll adjust it over time to reach the amount that’s right for you. Your doctor will ultimately prescribe the smallest dosage that provides the desired effect.
The following information describes dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs.
Buspirone oral tablets are taken by mouth. They come in the following strengths: 5 milligrams (mg), 7.5 mg, 10 mg, 15 mg, and 30 mg.
Dosage for anxiety
To treat anxiety disorders, in most cases, your doctor will recommend a starting dose of 7.5 mg of buspirone taken by mouth twice per day. This will give you a daily dose of 15 mg. Then, your doctor may increase your dose every 2 to 3 days by 5 mg per day to reach the buspirone dose that’s best for you. The maximum dose of buspirone is 60 mg per day, or 30 mg taken twice daily.
What if I miss a dose?
If you miss your dose of buspirone, take it as soon as you remember. However, if it is almost time for your next dose, just skip your missed dose and continue with your normal dosing schedule. If you missed a dose of your buspirone and are unsure when to take your next dose, talk with your doctor or pharmacist. They can recommend when you should take your next dose.
To help make sure you don’t miss a dose, try using a medication reminder. This can include setting an alarm or timer on your phone or downloading a reminder app. A kitchen timer can work, too.
Will I need to use this drug long term?
Buspirone may be used as a long-term treatment. If you and your doctor determine that buspirone is safe and effective for you, you’ll likely take it long term.
You should not drink alcohol while taking buspirone oral tablets. This is because drinking alcohol during your buspirone treatment can raise your risk for side effects, such as headache or dizziness. It can also cause more serious side effects, such as trouble breathing or trouble concentrating.
If you drink alcohol, talk with your doctor before you start using buspirone.
Buspirone oral tablets can interact with several other medications. It can also interact with certain foods.
Different interactions can cause different effects. For instance, some interactions can interfere with how well a drug works. Other interactions can increase side effects or make them more severe.
Buspirone and other medications
Below is a list of medications that can interact with buspirone. This list does not contain all drugs that may interact with buspirone.
Before taking buspirone, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.
If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.
Types of drugs that you should not take with buspirone include:
- Monoamine oxidase inhibitors (MAOIs). You should never take buspirone with an MAOI or within 14 days of stopping an MAOI. This is because taking buspirone with an MAOI raises your risk for serotonin syndrome or hypertension (high blood pressure), which can be very serious. Examples of MAOIs include:
- tranylcypromine (Parnate)
- phenelzine (Nardil)
- selegiline (Emsam)
- linezolid (Zyvox)
- methylene blue by intravenous (IV) infusion (Provayblue)
Types of drugs that can interact with buspirone include:
- Haloperidol (Haldol). Taking buspirone with haloperidol may increase your risk for side effects from haloperidol. If you take these drugs together, your doctor may need to adjust your dose of buspirone.
- Antidepressants. Taking buspirone along with certain antidepressants may raise your risk for serotonin syndrome, which can be serious. If you take these drugs together, your doctor may monitor you more closely during treatment. Examples of antidepressants that may interact with buspirone include:
- nefazodone (may also raise your risk for side effects from buspirone if used together)
- Certain heart medications. Taking buspirone with certain heart medications may raise your risk for side effects from buspirone. If you take these drugs together, your doctor may need to adjust your buspirone dose. Examples of heart medications that may interact with buspirone include:
- diltiazem (Cardizem CD, others)
- verapamil (Verelan, others)
- Certain antibiotics or antifungals. Using buspirone with some antibiotics or antifungals may raise your risk for side effects from buspirone. If you take these drugs together, your doctor may need to change your dose of buspirone. Examples of antibiotics or antifungals that may interact with buspirone include:
- erythromycin (Ery-Tab)
- itraconazole (Sporanox, Tolsura)
- Rifampin (Rimactane). Taking buspirone with rifampin may make buspirone less effective. If you take these drugs together, your doctor may need to change your dose of buspirone.
- Dexamethasone. Using buspirone with dexamethasone may make buspirone less effective. If you take these drugs together, your doctor may need to change your dose of buspirone.
- Seizure medications. Using buspirone with certain seizure medications can make buspirone less effective. If you do take these drugs together, your doctor may need to adjust your buspirone dose. Examples of seizure medications that may interact with buspirone include:
- phenytoin (Dilantin)
- carbamazepine (Tegretol, others)
- Ritonavir (Norvir). Taking ritonavir with buspirone can increase your risk for side effects from buspirone. If you use these two drugs together, your doctor may need to change your dose of buspirone.
Buspirone and herbs and supplements
St. John’s wort may make buspirone less effective. If you take St. John’s wort, your doctor may recommend that you stop taking this herb before you start buspirone. Or they may prescribe a higher buspirone dosage than is typical. Talk with your doctor if you take St. John’s wort before you begin taking buspirone.
Buspirone and foods
Buspirone can interact with grapefruit or grapefruit juice. You should avoid consuming grapefruit or grapefruit juice during your treatment, as doing so can raise your risk for side effects from buspirone.
Buspirone can be taken with or without food. To learn more, see the “How to take buspirone” section below.
Here are answers to some frequently asked questions about buspirone oral tablets.
Can buspirone cause weight gain or weight loss?
Changes in weight, such as weight gain or weight loss, were reported by some people taking buspirone in certain clinical studies. However, it isn’t known for sure whether buspirone or another factor caused these changes. One
You may experience appetite changes related to changes in your anxiety symptoms after you start taking buspirone. This could result in eating more or fewer calories than you typically would, which could lead to weight changes.
Also, if you’re taking other drugs for anxiety or depression along with buspirone, these drugs may affect your weight. Examples of these drugs include:
- selective serotonin reuptake inhibitors (SSRIs), such as fluoxetine (Prozac) or escitalopram (Lexapro)
- serotonin-norepinephrine reuptake inhibitors (SNRIs), such as venlafaxine (Effexor XR) or duloxetine (Cymbalta)
Although it’s not common, if you do experience unexpected weight gain or loss while taking buspirone, talk with your doctor. They can recommend ways to maintain a weight that is healthy for you.
How does buspirone make you feel? Can it make you feel ‘high’?
No, buspirone should not make you feel “high.” But the drug can affect how you feel. Buspirone decreases your symptoms of anxiety and can make you feel restless, sleepy, or excited.
You should never snort buspirone. Snorting the drug will not make you feel “high.” In addition, snorting drugs can cause serious side effects, such as lung infections or damage to the inside of your nose.
If you have questions about how you’ll feel while taking buspirone, talk with your doctor.
Is buspirone an SSRI or benzodiazepine?
Does buspirone treat depression or problems with sleep?
However, in some cases, buspirone may be used off-label to treat other conditions, such as depression or sleep problems. Off-label drug use means that your doctor prescribes a medication for a use other than what it is approved for.
If you’re interested in taking buspirone to treat depression or sleep problems, talk with your doctor.
Does buspirone cause sexual side effects?
No, buspirone isn’t known to cause sexual side effects. In fact, it’s sometimes used to help treat sexual side effects caused by other drugs used to treat anxiety or depression.
Sexual side effects, such as libido (sex drive) changes, were reported by some people taking buspirone in certain clinical studies. However, it isn’t known for sure whether buspirone caused the sexual side effects.
Although sexual side effects are uncommon with buspirone, talk with your doctor if you experience them during your treatment. Your doctor can recommend ways to manage these side effects.
Is buspirone a controlled substance?
No, buspirone is not a controlled substance. A controlled substance has the potential to be misused or for people to become dependent on it. (Misuse means using a medication in a way other than how it was prescribed. Dependence is when you need a drug to feel or function as you typically do.)
Although buspirone is not a controlled substance, other medications that may be taken for anxiety are controlled substances. For example, anxiety medications such as alprazolam (Xanax), lorazepam (Ativan), diazepam (Valium), and clonazepam (Klonopin) are controlled substances.
If you have any concerns about taking buspirone, talk with your doctor or pharmacist.
How do you safely stop taking buspirone? Should you taper off?
How you should stop taking buspirone depends on your dose and other medications you’re taking. Always talk with your doctor before stopping any medications.
In some cases, your doctor may recommend that you switch to a different medication to treat your condition. If your dose of buspirone is low, they may recommend just stopping buspirone and switching to another treatment option.
If you take a higher dose of buspirone, your doctor may recommend slowly decreasing your dose over time. This helps your body adjust to the change.
If you have specific questions about how to stop your buspirone treatment, talk with your doctor or pharmacist.
Does buspirone interact with stimulants such as caffeine and Adderall?
However, taking buspirone with medications that can increase your serotonin levels, such as Adderall, can cause your serotonin levels to get too high. This can raise your risk for serotonin syndrome, a condition that can be serious and even life threatening.
For a list of medications that may interact with buspirone, see the “Buspirone interactions” section above. If you still have additional questions or concerns, talk with your doctor or pharmacist.
Buspirone oral tablets are FDA-approved to treat anxiety disorders, such as generalized anxiety disorder, in adults. People with anxiety may have symptoms such as feeling stressed, apprehensive, or nervous.
It’s not known exactly what buspirone’s mechanism of action is. (The mechanism of action of a drug explains how it works.) It’s possible that buspirone works by affecting levels of chemicals in your brain called serotonin and dopamine. These chemicals may help reduce symptoms of anxiety.
How long does it take to work? Does it start working immediately?
Buspirone will begin working after you take your first dose of medication. However, unlike some other anxiety medications, it doesn’t reach its full effect right away. Because buspirone affects chemical levels in your brain, it can take 2 to 4 weeks before it reaches its full effect.
If you have anxiety attacks or need a medication that works more quickly than buspirone, talk with your doctor about other treatment options for your condition.
How long does it stay in your system?
Within 24 hours, most of a buspirone dose will be eliminated from your body.
Buspirone has a half-life of about 2 to 3 hours. (A half-life is how long it takes your body to get rid of half of the dose of medication.)
Other drugs are available that can treat anxiety disorders. Some may be a better fit for you than others. If you’re interested in finding an alternative to buspirone oral tablets, talk with your doctor. They can tell you about other medications that may work well for you.
Note: Some of the drugs listed here are used off-label to treat these specific conditions. Off-label drug use means using a drug for a purpose other than what it’s been approved for by the FDA.
Examples of other drugs that may be used to treat anxiety include:
- escitalopram (Lexapro)
- fluoxetine (Prozac)
- alprazolam (Xanax)
- clonazepam (Klonopin)
- propranolol (Inderal LA)
- diazepam (Valium)
- sertraline (Zoloft)
- tranylcypromine (Parnate)
- lorazepam (Ativan)
Some of these medications are taken daily, like buspirone. However, other medications on this list, such as alprazolam (Xanax), can also be used as needed for anxiety attacks or for anxiety symptoms. (Buspirone must be taken every day for it to work. It can’t be used as needed for anxiety symptoms).
You may wonder how buspirone compares with other medications that are prescribed for similar uses. Here is an overview of how buspirone compares with the brand-name drug Xanax:
|Form(s)||oral tablet||• oral tablet|
• oral tablet XR (extended release)
|Use(s)||anxiety disorders, such as generalized anxiety disorder, in adults||• generalized anxiety disorder|
• panic disorder, with or without agoraphobia
These drugs generally cause similar side effects. However, Xanax has
A boxed warning is the most serious warning from the Food and Drug Administration (FDA).
For details about these drugs and the side effects they may cause, refer to the prescribing information for buspirone oral tablet, Xanax, and Xanax XR. You can also talk with your doctor or pharmacist for details about how these drugs compare.
The Food and Drug Administration (FDA) approves prescription drugs such as buspirone oral tablets to treat certain conditions. Buspirone may also be used off-label for other conditions. Off-label drug use means using a drug for a purpose other than what it’s been approved for by the FDA.
Buspirone for anxiety
For information about anxiety, you can visit the Medical News Today anxiety hub.
Effectiveness for anxiety
Buspirone has been shown to be an effective treatment for anxiety disorders and short-term treatment of anxiety symptoms. It’s recommended as a treatment option for generalized anxiety disorder by the American Academy of Family Physicians. For information on how buspirone performed in clinical studies, see the drug’s prescribing information.
Buspirone for children
Buspirone is not FDA-approved for use in children. However, small studies have been done in children to see if buspirone may be a safe or effective treatment option. Buspirone may be prescribed off-label to treat anxiety in children.
If you have questions about off-label use of buspirone for treating anxiety in your child, talk with their doctor.
Buspirone is FDA-approved to treat anxiety disorders, such as generalized anxiety disorder, in adults. In some cases, your doctor may recommend taking buspirone along with other medications to treat your condition.
For example, your doctor may recommend a medication to take if you have anxiety attacks or breakthrough anxiety (a sudden worsening of anxiety symptoms) while taking buspirone. Examples of these medications include alprazolam (Xanax) or lorazepam (Ativan). If you have depression along with anxiety, your doctor may recommend another medication, such as bupropion (Wellbutrin SR or XL) or fluoxetine (Prozac).
Buspirone can interact with many medications, so before using buspirone, talk with your doctor about any other medications or supplements you take. Your doctor can determine if buspirone is safe to take with your other medications.
Buspirone doesn’t cause withdrawal symptoms when you stop taking it. However, if you want to stop taking buspirone, be sure to talk with your doctor first. In some cases, they may recommend slowly reducing your dose over time so your body can adjust to the change.
Buspirone is not known to cause drug dependence (needing the drug in order to feel or function as you typically would). Studies in both humans and animals did not show that buspirone can cause dependence or risk of misuse. However, because buspirone affects your brain, it’s still important for your doctor to monitor you for symptoms of dependence during your treatment.
If you have a history of dependence, tell your doctor before taking buspirone. They may monitor you more closely throughout your treatment.
Using more than the recommended dosage of buspirone oral tablets can lead to serious side effects.
Do not use more buspirone than your doctor recommends. It’s not known what the overdose dosage of buspirone may be.
Symptoms of an overdose of buspirone can include:
- nausea or vomiting
- stomach problems, like stomach pain or cramps
- pinpoint pupils (abnormally small pupils, which are the black part of your eye)
What to do in case of overdose
If you think you’ve taken too much of this drug, call your doctor. You can also call the American Association of Poison Control Centers at 800-222-1222 or use its online tool. But if your symptoms are severe, call 911 or your local emergency number, or go to the nearest emergency room right away.
It’s not known whether buspirone oral tablets are safe to take during pregnancy. Animal studies did not show an increased risk of problems for a fetus when pregnant animals were given buspirone. However, animal studies do not always reflect what may happen in humans.
If you’re pregnant or planning to become pregnant, talk with your doctor before taking buspirone. They may recommend a different medication to treat your condition. If you do take buspirone, your doctor may want to monitor you more closely.
It’s not known if buspirone oral tablets are safe to take during pregnancy. If you’re sexually active and you or your partner can become pregnant, talk with your doctor about your birth control needs during your buspirone treatment.
For more information about taking buspirone during pregnancy, see the “Buspirone and pregnancy” section above.
It’s unknown whether it’s safe to breastfeed while taking buspirone oral tablets. Animal studies have shown that the drug passes into animal milk. However, it’s not known if buspirone may also pass into the breast milk of humans. Animal studies don’t always predict what will happen in humans.
It’s also not known what effects buspirone may have on a child who is breastfed, if any.
If you’re currently breastfeeding or planning to breastfeed, talk with your doctor before using buspirone. They may recommend a different medication for your condition.
Before taking buspirone oral tablets, talk with your doctor about your health history. Buspirone may not be right for you if you have certain medical conditions or other factors affecting your health. These include:
- Liver problems. If you have any liver problems, tell your doctor before you start taking buspirone. This drug is broken down by your liver. If your liver doesn’t work as well as it should, buspirone levels could build up in your body. If you have liver problems, your doctor may recommend a lower dose of buspirone, or they may recommend a different treatment for your condition.
- Kidney problems. Your body gets rid of buspirone through your kidneys. If you have kidney problems, your body may not be able to clear the drug as it typically would. This can cause a buildup of buspirone levels in your body. If you have kidney problems, your doctor may recommend a different medication to treat your condition. Or in some cases, they may prescribe a lower dose of buspirone for you.
- Allergic reaction. If you’ve had an allergic reaction to buspirone or any of its ingredients, you should not take buspirone oral tablets. This is a contraindication to its use. (A contraindication is a condition or factor that would prevent you from taking the medication.) Ask your doctor what other medications are better options for you.
- Pregnancy. It’s not known if buspirone is safe to take during pregnancy. For more information, see the “Buspirone and pregnancy” section above.
- Breastfeeding. It’s not known whether buspirone is safe to use while breastfeeding. For more information, see the “Buspirone and breastfeeding” section above.
- Taking an MAOI. If you’re taking a monoamine oxidase inhibitor (MAOI), you should not take buspirone for at least 14 days after stopping the MAOI. For more information on this drug interaction, see the “Buspirone interactions” section above.
Note: For more information about the potential negative effects of buspirone, see the “Buspirone side effects” section above.
As with all medications, the cost of buspirone oral tablets can vary. The actual price you’ll pay depends on your insurance plan, your location, and the pharmacy you use.
Keep in mind that you may be able to get a 90-day supply of buspirone. If approved by your insurance company, getting a 90-day supply of the drug could reduce your number of trips to the pharmacy and help lower the cost. If you’re interested in this option, check with your doctor or your insurance company.
Before approving coverage for buspirone, your insurance company may require you to get prior authorization. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. The insurance company will review the prior authorization request and decide if the drug will be covered.
If you’re not sure if you’ll need to get prior authorization for buspirone, contact your insurance company.
Financial and insurance assistance
Financial assistance to help you pay for buspirone may be available.
Medicine Assistance Tool and NeedyMeds are two websites offering resources that may help decrease the price you pay for buspirone. They also offer tools to help you find low-cost healthcare, as well as educational resources. To learn more, visit their sites.
Buspirone may be available through a mail-order pharmacy. Using this service may help lower the drug’s cost and allow you to get your medication without leaving home.
If recommended by your doctor, you may be able to receive a 90-day supply of buspirone, so there’s less concern about running out of the medication. If you’re interested in this option, check with your doctor and your insurance company. Some Medicare plans may help cover the cost of mail-order medications.
If you don’t have insurance, you can ask your doctor or pharmacist about online pharmacy options.
You should take buspirone according to the instructions your doctor or healthcare professional gives you.
Buspirone comes as a tablet that’s taken orally (by mouth). In most cases, buspirone should be taken twice per day. However, always take buspirone as your doctor prescribes it.
When to take
In most cases, you should take your dose of buspirone twice per day. Try to take your dose at about the same times each day. This helps make sure you always have a consistent amount of the drug in your body.
To help make sure you don’t miss a dose, try using a medication reminder. This can include setting an alarm or timer on your phone or downloading a reminder app. A kitchen timer can work, too.
Taking buspirone with food
You can take your dose of buspirone with or without food. However, it’s important to stay consistent with how you take your dose.
Food can affect how buspirone is absorbed. If you begin your treatment by taking buspirone with food, you should always take your dose with food. Or if you begin your treatment by taking your dose on an empty stomach, you should continue doing so with each dose.
If you have any questions about taking buspirone, talk with your doctor or pharmacist.
Can buspirone be crushed, split, or chewed?
Some buspirone tablets have a score line on them. (This is a line printed across the tablets.) These tablets can be split along the score line if needed.
The manufacturer of buspirone hasn’t made a recommendation on whether the tablets can be crushed or chewed.
If you’re having trouble swallowing your buspirone tablets, talk with your doctor or pharmacist. They may be able to recommend buspirone tablets with a score line on them, so you can cut them to make them easier to swallow. They can also recommend other medications to treat your condition that may be easier to take.
When you get buspirone oral tablets from the pharmacy, the pharmacist will add an expiration date to the label on the bottle. This date is typically 1 year from the date they dispensed the medication.
The expiration date helps guarantee that the medication is effective during this time. The
How long a medication remains good can depend on many factors, including how and where you store the medication.
Buspirone tablets should be stored at a room temperature of 68°F to 77°F (20°C to 25°C) in a tightly sealed container away from light. Avoid storing this medication in areas where it could get damp or wet, such as bathrooms.
If you no longer need to take buspirone and have leftover medication, it’s important to dispose of it safely. This helps prevent others, including children and pets, from taking the drug by accident. It also helps keep the drug from harming the environment.
This article provides several useful tips on medication disposal. You can also ask your pharmacist for information about how to dispose of your medication.
Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.