Dupixent (dupilumab) is a brand-name prescription medication. The Food and Drug Administration (FDA) has approved it to treat the following conditions:

  • certain types of asthma in adults and children ages 6 years and older
  • certain types of eczema (atopic dermatitis) in adults and children ages 6 years and older
  • eosinophilic esophagitis in adults and children ages 12 years and older who weigh at least 40 kilograms (kg), about 88 pounds (lb)
  • chronic rhinosinusitis with nasal polyps in adults

Dupixent contains the active ingredient dupilumab, which is a biologic drug. It belongs to a class of drugs called monoclonal antibodies, which work on a specific part of your immune system.

Dupixent is given as a subcutaneous injection. It comes as single-dose prefilled syringes and pens.

For more information about Dupixent’s uses, refer to this article.

Drug details

Here are some details about Dupixent:

  • How it’s given: subcutaneous injection in single-dose prefilled pens or syringes
  • Biosimilar version: not available

Read on to learn about Dupixent and cost, as well as how to save money on prescriptions.

As with all medications, the price of Dupixent can vary. Factors that may affect the Dupixent injection price you’ll pay include:

  • your treatment plan
  • your insurance coverage
  • the pharmacy you use
  • whether Dupixent has a savings program (see the “Financial and insurance assistance” section below)

To find out the Dupixent injection cost you’ll likely pay, talk with your doctor, pharmacist, or insurance provider.

Note: Dupixent is more expensive in the United States than in other countries. This is based on the drug and insurance regulations in each country. Talk with your doctor and insurance provider if you need a prescription filled in a different country.

Here are answers to some frequently asked questions about drug cost and Dupixent.

How can I determine the cost of Dupixent with and without insurance?

If you have a prescription for Dupixent, your pharmacist can tell you the retail price with insurance and without insurance. Even if you have insurance, you may have to pay the out of pocket cost for Dupixent according to your plan’s details. The manufacturer assistance program for Dupixent may be able to help you pay the out of pocket cost if you are eligible for the program.

Talk with your insurance provider as well to determine the exact cost of Dupixent per your plan. They can also tell you if you should fill your prescription at a specific pharmacy to get the lowest cost.

Your insurance provider can tell you what the cost of Dupixent would be per month, per year, and per dose. The annual cost of Dupixent may vary every year based on insurance plan changes, drug price changes, and whether you are eligible for assistance programs.

Do Dupixent’s costs vary based on whether it’s used for eczema, rhinosinusitis with nasal polyps, or asthma?

It’s possible. Because the dosage is different for different conditions, you may need a different amount of the drug. This will likely change the cost based on the number of syringes or pens you need for your dose.

If you have questions about the cost of Dupixent for your condition, talk with your pharmacist or insurance provider.

How much does the 300-mg/2-mL shot of Dupixent cost?

The cost of the 300-milligrams per 2-milliliters (mg/mL) shot of Dupixent will vary based on several factors. The cost of Dupixent may vary based on the strength and dosage form you use. Talk with your insurance provider or pharmacist for specific cost information.

Dupixent is only available as a brand-name drug. Dupixent contains the active ingredient dupilumab, which is a biologic drug. It doesn’t come in a biosimilar version. A biosimilar medication is a drug that’s similar to a brand-name medication (the parent drug).

Biologics are made from living cells. It’s not possible to make an exact copy of these drugs. A generic, on the other hand, refers to medications made from chemicals. A generic is an exact copy of the active drug in a brand-name medication.

Biosimilars are considered to be just as safe and effective as their parent drug. And like generics, biosimilars tend to cost less than brand-name medications.

Why are costs different for brand-name drugs vs. generic drugs?

Brand-name drugs can be expensive because of the research needed to test their safety and effectiveness. The manufacturer of a brand-name drug can sell it for up to 20 years. When the brand-name drug’s patent expires, multiple manufacturers can create generic versions. This marketplace competition may lead to lower costs for generics. Also, because generics contain the same ingredients as brand-name drugs, they don’t require the same costly testing.

If you take Dupixent long term, you may be able to lower its cost in the following ways:

Getting a 3-month supply

You may be able to get a 90-day supply of Dupixent. If approved by your insurance company, getting a 90-day supply of the drug could reduce your number of trips to the pharmacy and help lower the cost. If you’re interested in this option, check with your doctor, pharmacist, or insurance provider.

Using a mail-order pharmacy

Dupixent is a specialty medication and is typically only available through a mail-order specialty pharmacy. Using this type of service may help lower the drug’s cost and allow you to receive your medication without leaving home. Some Medicare plans may help cover the cost of mail-order medications. You may also be able to get a 90-day supply of the drug via mail order.

If you don’t have health insurance, talk with your doctor or pharmacist. They may be able to suggest online pharmacy options that could work for you.

If you need financial support to pay for Dupixent, or if you need help understanding your insurance coverage, help is available. For example:

  • A program called Dupixent MyWay provides a manufacturer coupon copay card. For more information and to find out if you’re eligible for support, call 844-387-4936 or visit the program website.
  • Some websites provide details about drug assistance programs, ways to make the most of your insurance coverage, and links to savings cards and other services. Two such websites are:

To learn more about saving money on prescriptions, check out this article.

Now that you’ve learned about cost and Dupixent, you may still have some questions. Talk with your doctor or pharmacist, who can provide personalized guidance about cost issues related to Dupixent. But if you have health insurance, you’ll need to talk with your insurance provider to learn the actual cost you would pay for Dupixent.

Here are some other resources you may find helpful:

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.