Evenity (romosozumab-aqqg) is a brand-name drug that’s prescribed for osteoporosis after menopause in some adults. Evenity comes as a subcutaneous injection that’s given by your doctor or another healthcare professional.

Evenity is a biologic and belongs to a drug class called sclerostin inhibitors. Evenity is not available in a biosimilar version.

Keep reading for specific information about the dosage of Evenity, including its strength and how the medication is given. For a comprehensive look at Evenity, see this article.

Note: This article describes typical dosages for Evenity provided by the drug’s manufacturer. However, your doctor will prescribe the Evenity dosage that’s right for you.

Below is information about Evenity’s form, strength, and dosage.

Evenity’s form

Evenity comes as a liquid solution in single-use prefilled syringes for subcutaneous injection. Your doctor or another healthcare professional will give your injections at your doctor’s office or in a clinic or hospital.

Evenity’s strength

Evenity prefilled syringes come in one strength: 105 milligrams (mg) per 1.17 milliliters (mg/mL)

Typical dosage

The following information describes the dosage of Evenity that’s commonly prescribed or recommended.

Dosage for postmenopausal osteoporosis

Evenity’s typical dosage for postmenopausal osteoporosis is 210 mg per month. Each 210-mg dose requires two prefilled syringes. So your doctor will give you two injections, one after the other.

Long-term treatment

Evenity is meant to be given once a month for 12 months. If you and your doctor determine that Evenity is safe and effective for you, you’ll receive Evenity for 12 months.

Talk with your doctor if you have questions about your treatment plan.

Evenity is given by subcutaneous injection.

Your doctor will inject the medication under the skin of your upper arm, abdomen, or thigh. They’ll take care to avoid skin that’s red, tender, hard, or bruised. They’ll also avoid areas with stretch marks or scars.

If you have questions about how Evenity is given, talk with your doctor.

If you miss an appointment for your Evenity injection, reschedule it as soon as possible. Your next dose will be 1 month after the rescheduled dose.

To help make sure that you don’t miss a dose, try using a medication reminder. This can include setting an alarm or putting a note where you’ll see it, such as on your bathroom mirror or bedside table. You could also download a reminder app on your phone.

The manufacturer of Evenity has an appointment reminder program called the Bone Matters Program. To learn more and sign up to receive appointment reminders, visit the program website.

Below are some questions about Evenity’s dosage.

Is the dosage of Evenity similar to the dosage of Prolia?

No, the dosage of Evenity is different than Prolia’s dosage. Similar to Evenity, Prolia is given as a subcutaneous injection that can be used to treat osteoporosis in certain adults. With Evenity, you’ll receive two injections once a month for 12 months. Prolia’s typical dosage is one injection every 6 months for as long as your doctor recommends the treatment. To learn more about Prolia dosages, see this article.

If you have questions about which drug is best for you, talk with your doctor.

Does Evenity have a recommended dosage for males?

No, Evenity doesn’t have a recommended dosage for males.* The drug hasn’t been studied in males and isn’t approved by the Food and Drug Administration (FDA) to treat osteoporosis in males. It’s approved to treat postmenopausal osteoporosis in females.* You can learn more about Evenity’s uses in this article.

Talk with your doctor about osteoporosis treatment options that are right for you. To learn more about osteoporosis in males, read this article.

* Sex and gender exist on spectrums. Use of the term “female” and “male” in this article refers to sex assigned at birth.

The dosages in this article are typical dosages provided by the drug manufacturer. If your doctor recommends Evenity for you, they’ll prescribe the dosage that’s right for you. If you have questions about the dosage of Evenity that’s best for you, talk with your doctor.

Besides learning about dosage, you may want other information about Evenity. These additional articles might be helpful:

  • More about Evenity. For information about other aspects of Evenity, refer to this article.
  • Side effects. To learn about side effects of Evenity, see this article. You can also look at the Evenity prescribing information.
  • Drug comparison. Find out how Evenity compares with Prolia and Forteo.
  • Cost. If you’d like to learn about Evenity and cost, see this article.
  • Details about your condition. For details about your condition, see our list of osteoporosis articles.

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.