Galafold (migalastat) is a brand-name drug that’s prescribed to treat Fabry disease in certain adults. Galafold comes as a capsule that’s typically taken once every other day.

Galafold belongs to a drug class called alpha-galactosidase A (alpha-Gal A) pharmacological chaperones. Galafold is not available in a generic version.

Keep reading for specific information about the dosage of Galafold, including its strength and how to take the medication. For a comprehensive look at Galafold, see this article.

Note: This article describes typical dosages for Galafold provided by the drug’s manufacturer. When taking Galafold, always follow the dosage prescribed by your doctor.

The typically recommended dosage for Galafold is described below.

Galafold form

Galafold comes as an oral capsule.

Galafold strength

Galafold comes in one strength of 123 milligrams (mg).

Typical dosages

The following information describes the dosage that is commonly prescribed or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs.

Dosage for Fabry disease

The recommended dosage of Galafold for Fabry disease is 123 mg taken once every other day.

For more information about your specific dosage, talk with your doctor.

Long-term treatment

Galafold is meant to be taken as a long-term treatment. If you and your doctor determine that Galafold is safe and effective for you, you’ll likely take it long term.

Before you start taking Galafold, your doctor will discuss your treatment plan with you.

Galafold comes as an oral capsule that you swallow whole. Do not divide, crush, chew, or place the capsule in water. Your doctor will likely recommend taking Galafold on an empty stomach. This means 2 hours before and at least 2 hours after a meal.

It may be helpful to take Galafold around the same time of day. This helps maintain a steady level of the drug in your body so Galafold can work effectively.

If you have trouble swallowing capsules, see this article for tips on how to take this form of medication.


Some pharmacies offer labels with large print, braille, or a code you scan with a smartphone to convert text to speech. If your local pharmacy doesn’t have these options, your doctor or pharmacist might be able to recommend a pharmacy that does.

If you’re having trouble opening medication bottles, ask your pharmacist about putting Galafold in an easy-open container. They also may recommend tools that can make it easier to open bottles.

If you miss a dose of Galafold, take it only if it’s within 12 hours of the time your scheduled dose should have been taken. If it’s been more than 12 hours since your regularly scheduled time, skip the missed dose. Then, take your dose on your next scheduled dosing day according to the every-other-day schedule.

Do not take two doses to make up for the missed one, or take Galafold 2 days in a row. If you’re not sure whether you should take a missed dose or skip it, talk with your doctor or pharmacist.

To help make sure that you don’t miss a dose, try using a medication reminder. This can include setting an alarm or putting a note where you’ll see it, such as on your bathroom mirror or bedside table.

The manufacturer of Galafold also has an app, called Galafold MyDay, that can help you remember when to take your dose. You can find more information about the app here.

It’s important that you do not take more Galafold than your doctor prescribes. For some medications, taking more than the recommended amount may lead to harmful effects or overdose.

If you take more than the recommended amount of Galafold

Call your doctor right away if you believe you’ve taken too much Galafold. Another option is to call America’s Poison Centers at 800-222-1222 or use its online tool. If you have severe symptoms, immediately call 911 or your local emergency number, or go to the nearest emergency room.

Below are some frequently asked questions about Galafold.

Should I take my dose of Galafold before or after food?

Galafold should be taken on an empty stomach. You should not eat any food for at least 2 hours before taking Galafold. After taking your dose, you should wait another 2 hours to eat.

During the time you can’t eat (4 hours total), you can drink clear liquids, such as water, fruit juices without pulp, and carbonated beverages that don’t contain caffeine.

Talk with your doctor if you have any questions about what you can eat or drink around the time of your Galafold dose.

How long does it take for Galafold to start working?

Galafold starts to work after your first dose. Because of how the drug works, you likely won’t feel the drug working in your body. But your doctor will monitor you during treatment to check whether the drug is working to treat your condition.

Talk with your doctor if you have questions about what to expect with Galafold treatment.

The dosages in this article are typical dosages provided by the drug’s manufacturer. If your doctor recommends Galafold for you, they will prescribe the dosage that’s right for you. Always follow the dosage that your doctor prescribes.

As with any drug, never change your dosage of Galafold without your doctor’s recommendation. If you have questions about the dosage of Galafold that’s best for you, talk with your doctor.

Besides learning about dosage, you may want other information about Galafold. These additional articles might be helpful:

  • More about Galafold: For information about other aspects of Galafold, refer to this article.
  • Side effects: To learn about side effects of Galafold, see the Galafold prescribing information.

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.