Glyxambi (empagliflozin/linagliptin) is a brand-name prescription medication. The Food and Drug Administration (FDA) has approved it in adults with type 2 diabetes to:

Glyxambi contains two medications: empagliflozin and linagliptin. Empagliflozin belongs to a class of drugs known as sodium glucose cotransporter 2 inhibitors. And linagliptin is classified as a dipeptidyl peptidase-4 inhibitor.

Glyxambi comes as a tablet that you swallow. There is no generic form of Glyxambi at this time.

* In this case, empagliflozin reduces the risk of death due to cardiovascular disease.

Dosage summary

The following chart summarizes Glyxambi’s dosage. Milligrams is abbreviated as mg. Your doctor will determine the dosage that’s best for you.

Starting dosageMaximum dosage
10 mg empagliflozin/5 mg linagliptin once per day25 mg empagliflozin/5 mg linagliptin once per day

For information about the dosage of Glyxambi, including its strengths and how to take the drug, keep reading. For a comprehensive look at Glyxambi, see this article.

This article describes typical dosages for Glyxambi provided by the drug’s manufacturer. When taking Glyxambi, always follow the dosage prescribed by your doctor.

Below is information about Glyxambi’s recommended dosages for its approved uses.

Glyxambi form

Glyxambi comes as an oral tablet.

Glyxambi strengths

Glyxambi comes in two strengths:

  • 10 mg empagliflozin/5 mg linagliptin (This strength may also be written as 10-5 mg.)
  • 25 mg empagliflozin/5 mg linagliptin (This strength may also be written as 25-5 mg.)

Typical dosages

The following information describes dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs.

Typically, your doctor will start you on a dosage of 10 mg empagliflozin/5 mg linagliptin once per day. If this amount doesn’t work for you, they’ll likely increase your dose to the maximum dose of 25 mg empagliflozin/5 mg linagliptin. Your doctor will ultimately prescribe the smallest dosage that provides the desired effect.

Long-term treatment

Glyxambi is meant to be a long-term treatment. If you and your doctor determine that Glyxambi is safe and effective for you, you’ll likely take it long term.

Glyxambi comes as a tablet that you swallow. You’ll typically take your dose once per day, in the morning. You can take your dose with or without food.

If you have trouble swallowing tablets, see this article for tips on how to take this form of medication. You can also talk with your doctor or pharmacist.

Accessible drug labels and containers

If you’re having trouble reading your prescription label, talk with your doctor or pharmacist. Some pharmacies offer labels with large print, braille, or a code you scan with a smartphone to convert text to speech. If your local pharmacy doesn’t have these options, your doctor or pharmacist might be able to recommend a pharmacy that does.

If you’re having trouble opening medication bottles, ask your pharmacist about putting Glyxambi in an easy-open container. They also may recommend tools that can make it easier to open bottles.

If you miss a dose of Glyxambi, take it as soon as you remember. If it’s almost time for the next dose, take that dose and skip the missed dose. Do not take more than one dose to make up for the missed one. Doing so may increase your risk of side effects.

To help make sure that you don’t miss a dose, try using a medication reminder. This can include setting an alarm or using a timer. You could also download a reminder app on your phone.

It’s important that you don’t use more Glyxambi than your doctor prescribes. For some medications, taking more than the recommended amount may lead to side effects or overdose.

If you take more than the recommended amount of Glyxambi

Call your doctor right away if you believe you’ve taken too much Glyxambi. Another option is to call the American Association of Poison Control Centers at 800-222-1222 or use its online tool. If you have severe symptoms, immediately call 911 or your local emergency number, or go to the nearest emergency room.

The dosages in this article are typical dosages provided by the drug’s manufacturer. If your doctor recommends Glyxambi for you, they will prescribe the dosage that’s right for you. Always follow the dosage that your doctor prescribes for you.

As with any drug, never change your dosage of Glyxambi without your doctor’s recommendation. If you have questions about the dosage of Glyxambi that’s right for you, talk with your doctor.

Besides learning about dosage, you may want other information about Glyxambi. These additional articles might be helpful:

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.