Izervay (avacincaptad pegol) is a brand-name drug prescribed for adults with geographic atrophy (GA) from age-related macular degeneration (AMD). Izervay is typically given once per month as an eye injection by a doctor.
Izervay belongs to a drug class called complement inhibitors. Izervay isn’t available in a generic version.
Keep reading for specific information about the dosage of Izervay, including its strength and how the medication is given. For a comprehensive look at Izervay, see this article.
Note: This article describes the typical dosage of Izervay provided by the drug’s manufacturer. However, your doctor will prescribe the Izervay dosage that’s right for you.
Below is information about Izervay’s form, strength, and dosage.
Izervay form
Izervay comes as a solution in a single-dose vial. It’s given as an eye injection by an eye doctor.
Izervay strength
Izervay comes in one strength of 2 milligrams (mg), which is 0.1 milliliters (mL) of a 20 mg/mL solution.
Typical dosages
The following information describes the dosage that’s commonly prescribed or recommended. However, your doctor will determine the best dosage to fit your needs.
Dosage for geographic atrophy
Doctors may use Izervay to treat GA, which can occur when AMD progresses. Your doctor will determine whether one or both eyes need treatment with Izervay.
The recommended dose for GA is one injection of 2 mg (0.1 mL of a 20 mg/mL solution) given into the affected eye. You’ll receive an injection about every 28 days (per month).
For more information about your specific dosage, talk with your doctor.
Long-term treatment
Izervay is typically given for up to 12 months of treatment. If you and your doctor determine that it’s safe and effective for you, you’ll likely receive Izervay for no more than 12 months.
Talk with your doctor if you have questions about how long you can expect to take Izervay.
Your eye doctor will give you the injection of Izervay in their office. Before every injection, your doctor will check the pressure within your eye.
For the injection, they’ll give medications to numb your eye and prevent infection. If both eyes need Izervay, these steps will be repeated for the second eye. Since each vial of Izervay supplies a single dose, the second eye will require a new vial.
After the injection, your doctor will monitor your eye pressure again.
Tell your doctor right away about pain, redness, blurry vision, or light sensitivity following the injection. These symptoms may be serious side effects of the drug that need to be treated immediately.
If you have questions about how Izervay is given, talk with your doctor. There’s also more information about starting Izervay on the manufacturer’s website.
To learn more about your condition, explore this list of GA articles.
Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.