Linezolid is a generic drug that’s prescribed for certain types of infections in adults and children. The medication is available as the brand-name drug Zyvox. The cost of linezolid with and without insurance can depend on several factors.

Specifically, linezolid is approved by the Food and Drug Administraiton (FDA) to treat the following infections in adults and children:

  • hospital-acquired pneumonia caused by Staphylococcus aureus or Streptococcus pneumoniae
  • community-acquired pneumonia caused by Streptococcus pneumoniae or methicillin-susceptible Staphylococcus aureus
  • infections of the skin and skin structures caused by Staphylococcus aureus, Streptococcus pyogenes, or Streptococcus agalactiae
  • Vancomycin-resistant enterococcus faecium infections

Linezolid retail price
Save up to $434 per fill off of the retail price
The retail price of Linezolid is $1396. Save up to $434 per fill off of the retail price.

As with all medications, the cost of linezolid can vary. Factors that may affect the price you’ll pay include your treatment plan, your insurance coverage, and the pharmacy you use. It may also depend on the cost of the visit to your healthcare professional to receive doses of linezolid, if your doctor prescribes the intravenous form of this medication.

To find out what the cost of linezolid will be for you, talk with your doctor, pharmacist, or insurance provider. Or look below in the next section to learn how much you can save by using an Optum Perks coupon.

To save money on your Linezolid prescription, explore these Optum Perks coupons.

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Save on Linezolid without insurance.

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3000ml linezolid (2 Packages)

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Simply show the Optum Perks coupon at your preferred pharmacy and instantly save without using insurance. The coupon doesn’t expire, so be sure to save it for use with refills.

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Retail price refers to the manufacturer’s published list price and is up to date as of 3/2023. Retail and discounted prices are U.S.-only and can vary based on region and pharmacy. We cannot guarantee that the discounted price listed here will exactly match the price at your pharmacy. Please contact your pharmacy for the exact price.

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Linezolid is a generic drug, which means it’s an exact copy of the active drug in a brand-name medication. A generic drug is considered to be as safe and effective as the original drug. And generics tend to cost less than brand-name drugs.

Linezolid is available as the brand-name drug Zyvox. If your doctor has prescribed linezolid and you’re interested in using Zyvox instead, talk with your doctor. They may have a preference for one version or the other. You’ll also need to check with your insurance provider, as it may only cover one or the other.

To find out how the cost of this brand-name drug compares with the cost of linezolid, talk with your doctor, pharmacist, or insurance provider.

If you need financial support to pay for linezolid, consider looking into websites that offer cost resources and information. Two such organizations are:

These sites can provide details about drug assistance programs, ways to make the most of your insurance coverage, and links to savings cards and other services.

Here are answers to some frequently asked questions about drug cost and linezolid.

Does the linezolid 600-mg oral tablet cost less than the injection form of the drug?

It depends. Your cost of linezolid can vary based on the strength, form, and quantity of drug your doctor prescribes for you. It also depends on your insurance plan, if you have one.

If you have questions about which form of linezolid is best for your condition, talk with your doctor. To find out more about the cost of linezolid, contact your insurance plan administrator or your pharmacist.

What is the cost of linezolid without insurance?

The price you’ll pay for linezolid if you don’t have insurance can vary based on several factors. But typically, the cost is higher for those without insurance.

There are other factors that could affect what you pay for this drug. These include:

  • the quantity you’re prescribed (such as a 90-day or 30-day supply)
  • whether you apply and qualify for any available savings programs
  • your dosage
  • the pharmacy you use
  • the form of the drug you’re prescribed (such as oral tablet, oral suspension, or intravenous (IV) injection)

To learn the exact cost you’d pay for this medication without insurance, ask your doctor or pharmacist. You may also want to contact several pharmacies to compare their prices for linezolid.

Check out Optum Perks* for estimates of linezolid’s price when using coupons from the site. (Optum Perks coupons cannot be used with insurance benefits or copays.)

* Optum Perks is a sister site of Medical News Today.

How does linezolid’s cost compare with that of medications such as vancomycin?

The price you’d pay for linezolid versus that of vancomycin depends on various factors.

For instance, the form of the drug may affect its price. Linezolid is available as an oral tablet, oral liquid suspension, and IV injection. Vancomycin is available as an oral capsule, oral solution, and IV injection.

There are additional factors that can affect your prescription cost, including:

  • the length of your treatment
  • whether there are payment assistance programs for your prescribed treatment
  • whether you’re paying out of pocket or have insurance

To learn more about the cost of linezolid compared with other treatments for your condition, talk with your doctor, pharmacist, or insurance provider.

Below is information you may want to consider if you have insurance and receive linezolid.

Prior authorization. If you have insurance, your insurance company may require prior authorization before it covers linezolid. This means the company and your doctor will discuss linezolid in regard to your treatment. The insurance company will then determine whether the medication is covered. If a drug requires prior authorization but you start treatment without the prior approval, you could pay the full cost of the medication. You can ask your insurance company whether linezolid requires prior authorization.

Type of insurance coverage. Linezolid may be given by your doctor or another healthcare professional. If you have insurance, the price of your linezolid doses may be billed through your medical coverage instead of the prescription drug portion of your insurance plan. This depends on your specific insurance plan and where you receive your linezolid doses, such as an infusion clinic or a hospital. If you have questions about this process, contact your doctor or your insurance provider.

Now that you’ve learned about cost and linezolid, you may still have some questions. Talk with your doctor or pharmacist, who can provide personalized guidance about cost issues related to linezolid. But if you have health insurance, you’ll need to talk with your insurance provider to learn the actual cost you’d pay for linezolid.

Here are some other resources you may find helpful:

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.