Nurtec ODT (rimegepant) is a prescription brand-name medication. The Food and Drug Administration (FDA) has approved it to treat migraine episodes that occur with or without aura in adults. It is also approved to help prevent episodic migraine in adults.

Nurtec ODT is an orally disintegrating tablet.

Nurtec ODT belongs to a class of drugs called calcitonin gene-related peptide (CGRP) receptor antagonists. There is no generic form of Nurtec ODT at this time.

Dosage summary

The following chart summarizes Nurtec ODT’s dosage. Milligrams is abbreviated as mg. Your doctor will determine the dosage that’s best for you.

SituationRecommended dosageMaximum dosageMaximum doses in a 30-day period
acute treatment of migraine75 mg once per day as needed75 mg every 24 hours18 doses
prevention of episodic migraine75 mg every other dayunknownunknown

For information about the dosage of Nurtec ODT, including its strength and how to take the drug, keep reading. For a comprehensive look at Nurtec ODT, see this article.

This article describes typical dosages for Nurtec ODT provided by the drug’s manufacturer. When taking Nurtec ODT, always follow the dosage and administration instructions prescribed by your doctor.

Below is important information about Nurtec ODT dosage for its approved uses.

Nurtec ODT form

Nurtec ODT is an orally disintegrating tablet. (This means it dissolves when placed in your mouth, on or under your tongue.)

Nurtec ODT strength

Nurtec ODT comes in one strength: 75 milligrams (mg).

Typical dosages

The following information describes dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs.

Dosage for acute migraine treatment

The typical dosage of Nurtec ODT for acute (immediate) migraine treatment is 75 mg, once per day as needed. This means you will take Nurtec ODT only when you have a migraine attack. The maximum dose is 75 mg every 24 hours.

Dosage for migraine prevention

Nurtec ODT’s dosing for preventing episodic migraine is 75 mg every other day. In this case, you will take Nurtec ODT on a schedule (every other day).

Long-term treatment

Nurtec ODT is meant to be used as needed to treat acute migraine attacks. This means you may use it as needed over a long period. To prevent episodic migraine, you may use Nurtec ODT on a schedule over a long period.

If you and your doctor determine that Nurtec ODT is safe and effective for you, you’ll likely take it long term since migraine can be a chronic condition.

The Nurtec ODT dosage your doctor prescribes will depend on several factors. These include:

  • the type and severity of the condition you’re using Nurtec ODT to treat
  • other drugs you’re taking
  • how well your kidneys and liver function

Other medical conditions you have can also affect your Nurtec ODT dosage.

Dosage adjustments

Your doctor may need to adjust your dosage if you take other medications in combination with Nurtec ODT. Some drugs may cause you to have too much or too little Nurtec ODT in your body.

Certain medications that affect enzymes in the body can interact with Nurtec ODT. These drugs are known as CYP3A4 inhibitors and CYP3A inducers. Examples of CYP3A4 inhibitors include Nizoral (ketoconazole) and Verelan (verapamil). And examples of CYP3A inducers include Rifadin (rifampin) or Dilantin (phenytoin).

Drugs that affect P-glycoprotein can also increase levels of Nurtec ODT in your body. These drugs include Noxafil (posaconazole) and propafenone.

Tell your doctor about all of the medications you take before starting treatment with Nurtec ODT. They may adjust how often you take the drug.

Nurtec ODT comes an an orally disintegrating tablet. You can take this tablet by letting it dissolve under your tongue or on top of your tongue. Let the tablet dissolve fully on your tongue, and then swallow it without water. You should avoid eating or drinking until you’ve swallowed the dissolved tablet. Do not crush, split, or chew Nurtec ODT tablets.

To treat an acute (immediate) migraine attack, take Nurtec ODT as soon as you have symptoms of migraine or aura. To prevent episodic migraine, take Nurtec ODT every other day, as scheduled.

Accessible drug labels and containers

If you’re having trouble reading your prescription label, talk with your doctor or pharmacist. Some pharmacies offer labels with large print, braille, or a code you scan with a smartphone to convert text to speech. If your local pharmacy doesn’t have these options, your doctor or pharmacist might be able to recommend a pharmacy that does.

If you’re having trouble opening medication bottles, ask your pharmacist about putting Nurtec ODT in an easy-open container. They also may recommend tools that can make it easier to open bottles.

If you miss a Nurtec ODT dose for prevention of episodic migraine and have questions about what to do, talk with your doctor or pharmacist.

To help make sure that you don’t miss a dose, try using a medication reminder. This can include setting an alarm or using a timer. You could also download a reminder app on your phone.

It is important that you do not use more Nurtec ODT than your doctor prescribes. Taking more than the recommended amount of some medications may lead to side effects or overdose.

If you take more than the recommended amount of Nurtec ODT

Call your doctor right away if you believe you’ve taken too much Nurtec ODT. Another option is to call the American Association of Poison Control Centers at 800-222-1222 or use its online tool. If you have severe symptoms, immediately call 911 or your local emergency number, or go to the nearest emergency room.

The dosages in this article are typical dosages provided by the drug’s manufacturer. If your doctor recommends Nurtec ODT for you, they will prescribe the right dosage for you. Always follow the dosage that your doctor prescribes for you.

As with any drug, never change your dosage of Nurtec ODT without your doctor’s recommendation. If you have questions about the dosage of Nurtec ODT that’s right for you, talk with your doctor.

Besides learning about dosage, you may want other information about Nurtec ODT. These additional articles might be helpful to you:

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.