Tabrecta (capmatinib) is a brand-name prescription medication. The Food and Drug Administration (FDA) has approved it to treat a type of metastatic non-small cell lung cancer* in adults. The cancer must have a mesenchymal-epithelial transition (MET) gene mutation.

Tabrecta contains the active ingredient capmatinib and belongs to a drug class called kinase inhibitors.

Tabrecta comes as an oral tablet. It’s not currently available as a generic medication.

* Tabrecta received accelerated approval for this use based on early clinical trials. Continued approval of the drug will depend on additional clinical trial data.

Dosage summary

The following chart summarizes Tabrecta’s dosage. “Milligrams” is abbreviated as “mg.” Your doctor will determine the dosage that’s best for you.

Tabrecta formTabrecta strengthsRecommended doseDosing schedule
oral tablet150 mg, 200 mg400 mgtwo times per day

For information about the dosage of Tabrecta, including its strengths and how to take the drug, keep reading. For a comprehensive look at Tabrecta, see this article.

This article describes the typical dosage for Tabrecta provided by the drug’s manufacturer. When taking Tabrecta, always follow the dosage prescribed by your doctor.

This section describes the typical dosage of Tabrecta.

Tabrecta form

Tabrecta comes as an oral tablet.

Tabrecta strengths

Tabrecta is available in two strengths: 150 milligrams (mg) and 200 mg.

Typical dosages

The following information describes the dosage that’s commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs.

Dosage for metastatic non-small cell lung cancer

Tabrecta is approved to treat a type of metastatic non-small cell lung cancer with a certain gene mutation.

For this purpose, the recommended dose of Tabrecta is 400 mg. You’ll likely be advised to take the medication two times per day.

Be sure to tell your doctor if you have any side effects while taking Tabrecta. They may prescribe a lower dosage: 200 mg or 300 mg, two times per day. (For information about Tabrecta’s side effects, you can refer to this article.)

Children’s dosage

Tabrecta is not approved for use in children.

Long-term treatment

Tabrecta is meant to be used as a long-term treatment. If you and your doctor determine that Tabrecta is safe and effective for you, you’ll likely take it long term.

The Tabrecta dosage your doctor prescribes will depend on a few factors. These include:

  • how well you tolerate Tabrecta
  • other medications you take

Other medical conditions you have can also affect your Tabrecta dosage.

Dosage adjustments

Your doctor may decrease your Tabrecta dose if you experience certain side effects, such as nausea or increased levels of liver enzymes (proteins). If you still have side effects with the lower dose, your doctor may have you stop taking Tabrecta permanently.

For information about Tabrecta’s side effects, you can refer to this article.

Tabrecta comes as an oral tablet that you swallow whole. You should not crush, chew, or split the medication. You can take Tabrecta with or without food.

Try to take Tabrecta at the same time each day, about 12 hours apart. This helps maintain a steady level of the drug in your body so Tabrecta can work effectively.

If you have trouble swallowing tablets, see this article for tips on how to take this form of medication. You can also talk with your doctor or pharmacist.

Accessible drug labels and containers

If you’re having trouble reading your prescription label, talk with your doctor or pharmacist. Some pharmacies offer labels with large print, braille, or a code you scan with a smartphone to convert text to speech. If your local pharmacy doesn’t have these options, your doctor or pharmacist might be able to recommend a pharmacy that does.

If you’re having trouble opening medication bottles, ask your pharmacist about putting Tabrecta in an easy-open container. They also may recommend tools that can make it easier to open bottles.

If you miss a dose of Tabrecta or vomit after a dose, wait until your next scheduled time to take the next dose. You should not take a second dose to make up for a missed dose.

To help make sure that you don’t miss a dose, try using a medication reminder. This can include setting an alarm or using a timer. You could also download a reminder app on your phone.

It’s important that you don’t take more Tabrecta than your doctor prescribes. For some medications, taking more than the recommended amount may lead to side effects or overdose.

If you take more than the recommended amount of Tabrecta

Call your doctor right away if you believe you’ve taken too much Tabrecta. Another option is to call the American Association of Poison Control Centers at 800-222-1222 or use its online tool. If you have severe symptoms, immediately call 911 or your local emergency number, or go to the nearest emergency room.

The dosage in this article is the typical dosage provided by the drug manufacturer. If your doctor recommends Tabrecta for you, they’ll prescribe the dosage that’s right for you. Always follow the dosage that your doctor prescribes for you.

As with any drug, never change your dosage of Tabrecta without your doctor’s recommendation. If you have questions about the dosage of Tabrecta that’s best for you, talk with your doctor.

Besides learning about dosage, you may want other information about Tabrecta. These additional articles might be helpful:

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.