Talzenna (talazoparib) is a brand-name drug that’s prescribed for certain types of breast and prostate cancers in adults. It comes as an oral capsule that’s typically taken once per day. The dosage can vary, depending on the condition it’s used to treat.

Talzenna is approved by the Food and Drug Administration (FDA) to treat the following conditions in adults:

Talzenna belongs to a drug class called poly adenosine diphosphate-ribose polymerase (PARP) inhibitors. Talzenna isn’t available in a generic version.

Keep reading for specific information about the dosage of Talzenna, including its strengths and how to take the medication. For a comprehensive look at Talzenna, see this article.

Note: This article describes typical dosages for Talzenna provided by the drug’s manufacturer. When taking Talzenna, always follow the dosage prescribed by your doctor.

Below is information about Talzenna’s form, strengths, and dosages.

Talzenna form

Talzenna comes as an oral capsule.

Talzenna strengths

Talzenna comes in six strengths:

  • 0.1 milligrams (mg)
  • 0.25 mg
  • 0.35 mg
  • 0.5 mg
  • 0.75 mg
  • 1 mg

Typical dosages

The following information describes dosages that are commonly prescribed or recommended in adults. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs. In some cases, doctors may adjust your dosage from those shown below.

Dosage for breast cancer

Doctors may prescribe Talzenna to treat certain types of breast cancer.

If your doctor prescribes Talzenna for your breast cancer, your dosage will likely be 1 mg once per day. If you develop bothersome side effects during Talzenna treatment, your doctor may lower your dose.

For more information about your specific dosage, talk with your doctor.

Dosage for prostate cancer

Talzenna is also approved to help treat certain types of prostate cancer. In this case, the drug is typically taken with another drug called enzalutamide (Xtandi).

If your doctor prescribes Talzenna for your prostate cancer, your dosage will likely be 0.5 mg once per day. If you develop bothersome side effects during Talzenna treatment, your doctor may lower your dose.

Talk with your doctor if you have questions about your dosage.

How to take Talzenna

Talzenna comes as an oral capsule that you swallow whole. Do not divide, open, chew, or dissolve the capsule in water. You may take your dose with or without food.

It may be helpful to take Talzenna around the same time of day. This helps maintain a steady level of the drug in your body so Talzenna can work effectively.

If you vomit or miss a dose of Talzenna, just take your next dose at your usual time. Do not take extra medication, as this can raise your risk of side effects.

If you have trouble swallowing capsules, see this article for tips on how to take this form of medication. You can also talk with your doctor or pharmacist.

Long-term treatment

Talzenna is meant to be taken long-term to help slow cancer growth and help prevent further spread. If the drug is no longer effective, your doctor recommend you stop taking it. They may also stop it if you develop bothersome side effects that can’t be managed with lower dosages

Before you start taking Talzenna, your doctor will discuss your treatment plan with you


Some pharmacies offer labels with large print, braille, or a code you scan with a smartphone to convert text to speech. If your local pharmacy doesn’t have these options, your doctor or pharmacist might be able to recommend a pharmacy that does.

If you’re having trouble opening medication bottles, ask your pharmacist about putting Talzenna in an easy-open container. They also may recommend tools that can make it easier to open bottles.

It’s important that you do not take more Talzenna than your doctor prescribes. For some medications, taking more than the recommended amount may lead to harmful effects or overdose.

If you take more than the recommended amount of Talzenna

Call your doctor right away if you believe you’ve taken too much Talzenna. Another option is to call America’s Poison Centers at 800-222-1222 or use its online tool. If you have severe symptoms, immediately call 911 or your local emergency number, or go to the nearest emergency room.

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.