Tyrvaya (varenicline solution) is a brand-name nasal spray that’s prescribed for dry eye disease. The cost of the drug with and without insurance can depend on several factors, such as whether Tyrvaya has a savings program.

Tyrvaya belongs to a drug class called partial nicotinic receptor agonists. Tyrvaya is not available in a generic version.

Read on to learn about Tyrvaya nasal spray and cost, as well as how to save money on prescriptions. If you’d like other information about Tyrvaya, refer to this article.

As with all medications, the cost of Tyrvaya can vary. Factors that may affect the price you’ll pay include:

  • your insurance coverage
  • the pharmacy you use
  • whether Tyrvaya has a savings program (see the “Financial and insurance assistance” section below)

To find out what the cost of Tyrvaya will be for you, talk with your doctor, pharmacist, or insurance provider.

Note: If you have insurance, your insurance company may require prior authorization before it covers Tyrvaya. This means the company and your doctor will discuss Tyrvaya in regard to your treatment. The insurance company will then determine whether the medication is covered. If a drug requires prior authorization and you start treatment without the prior approval, you could pay the full cost of the medication. You can ask your insurance company whether Tyrvaya requires prior authorization.

Here are answers to some frequently asked questions about drug cost and Tyrvaya.

Is there a copay card for Tyrvaya?

Yes. The manufacturer of Tyrvaya has a copay card savings program if you have private insurance coverage. This can save you money on the cost of Tyrvaya.

If you don’t have insurance coverage or have public insurance, such as Medicare or Medicaid, you don’t qualify for the copay card savings program.

Check with the program website or your insurance provider for more details on the copay card and savings.

What’s the cost of Tyrvaya with Medicare?

The cost of Tyrvaya with Medicare depends on your individual plan and benefits. For example, your cost may vary if you have a set copay for brand-name drugs such as Tyrvaya or if you must pay a percentage of the total cost of the drug.

Your cost may also depend on whether you must meet any prior authorization requirements before the drug is covered. This can affect your cost.

Reach out to your Medicare plan provider to find out about the cost of Tyrvaya for you.

Tyrvaya is only available as a brand-name drug. It doesn’t come in a generic version. A generic drug is an exact copy of the active drug in a brand-name medication.

Generics tend to cost less than brand-name drugs.


Brand-name drugs can be expensive because of the research needed to test their safety and effectiveness. The manufacturer of a brand-name drug can sell it for up to 20 years. When the brand-name drug’s patent expires, multiple manufacturers can create generic versions. This marketplace competition may lead to lower costs for generics. Also, because generics contain the same active ingredients as brand-name drugs, they don’t require the same costly testing.

If you take Tyrvaya long term, you may be able to lower its cost in the following ways.

Getting a 3-month supply

You may be able to get a 90-day supply of Tyrvaya. If approved by your insurance company, getting a 90-day supply of the drug could reduce your number of trips to the pharmacy and help lower the cost. If you’re interested in this option, check with your doctor, pharmacist, or insurance provider.

Using a mail-order pharmacy

Tyrvaya may be available through a mail-order pharmacy program called PhilRx. Using this type of service may help lower the drug’s cost and allow you to receive your medication without leaving home. You may also be able to get Tyrvaya through other mail-order pharmacies. Ask your doctor or insurance provider for more information on mail-order pharmacy programs that may provide cost savings.

Some Medicare plans may help cover the cost of mail-order medications. You may also be able to get a 90-day supply of the drug via mail order.

If you don’t have health insurance, talk with your doctor or pharmacist. They may be able to suggest online pharmacy options that could work for you.

If you need financial support to pay for Tyrvaya, or if you need help understanding your insurance coverage, help is available. For example:

  • A program called TEAMTyrvaya is available for Tyrvaya. For more information and to find out whether you’re eligible for support, call 877-393-0123 or visit the program website.
  • Some websites provide details about drug assistance programs, ways to make the most of your insurance coverage, and links to savings cards and other services. Two such websites are:

To learn more about saving money on prescriptions with or without insurance, check out this article.

Now that you’ve learned about cost and Tyrvaya, you may still have some questions. Talk with your doctor or pharmacist, who can provide personalized guidance about cost issues related to Tyrvaya.

However, if you have health insurance, you’ll need to talk with your insurance provider to learn the actual cost you would pay for Tyrvaya.

Here are some other resources you may find helpful:

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.