Ubrelvy (ubrogepant) is a brand-name drug that’s prescribed for migraine in adults. Ubrelvy comes as an oral tablet that’s typically taken as needed to treat migraine episodes. The dosage can vary depending on migraine severity.

Ubrelvy belongs to a drug class called calcitonin gene-related peptide (CGRP) antagonists. Ubrelvy is not available in a generic version.

Keep reading for specific information about the dosage of Ubrelvy, including its strengths and how to take the medication. For a comprehensive look at Ubrelvy, including details about its uses, see this article.

Note: This article describes typical dosages for Ubrelvy provided by the drug’s manufacturer. When taking Ubrelvy, always follow the dosage prescribed by your doctor.

Below is information about Ubrelvy’s recommended dosages.

Ubrelvy form

Ubrelvy comes as an oral tablet.

Ubrelvy strengths

Ubrelvy comes in two strengths:

  • 50 milligrams (mg)
  • 100 mg

Typical dosages

Typically, your doctor will start by prescribing a low dosage of Ubrelvy. Then they’ll adjust it over time to reach the amount that’s right for you. Your doctor will ultimately prescribe the smallest dosage that provides the desired effect.

The following information describes dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs.

Dosage for treatment of migraine

The typical dose of Ubrelvy to treat migraine in adults is 50 mg or 100 mg. You’ll take the drug as soon as you feel the symptoms of migraine, such as a headache.

If your symptoms don’t ease or they come back, your doctor may recommend taking a second dose. For example, if your doctor prescribes 50 mg, you’ll take another 50-mg dose as needed. However, you’ll need to wait at least 2 hours before taking your second dose.

Ubrelvy’s maximum dosage per day is 200 mg.

Note: It’s not known whether Ubrelvy is safe for treating more than eight migraine headaches per month. If you have frequent migraine episodes, your doctor may recommend another treatment for you. You can learn more about migraine frequency and treatment options in this article.

Long-term treatment

Ubrelvy isn’t meant to be taken as a long-term treatment. The drug treats migraine episodes as they occur. It’s not approved to help prevent them. If you and your doctor determine that Ubrelvy is safe and effective for you, you’ll likely take the drug only as needed.

If you have questions about your migraine treatment plan with Ubrelvy, talk with your doctor.

The Ubrelvy dosage your doctor prescribes will depend on several factors. These include:

Other medical conditions you have can also affect your Ubrelvy dosage.

* To find out about drug interactions with Ubrelvy, you can refer to this article.

Dosage adjustments

If you have serious liver or kidney problems, your doctor may prescribe a lower dosage of Ubrelvy.

Your doctor may prescribe a lower dose to start if you’re age 65 years or older. This is because there weren’t enough older adults taking Ubrelvy in clinical trials. So, it’s unclear whether this age group may respond differently to the medication.

If you have questions about dosage adjustments with Ubrelvy, talk with your doctor or pharmacist.

Ubrelvy comes as an oral tablet that you’ll swallow whole. Do not crush, chew, or split the tablets. You can take this medication with or without food.

At the first sign of migraine, you’ll take one dose of Ubrelvy. If your symptoms continue or ease then return, you may take a second dose according to your doctor’s instructions. However, be sure to wait at least 2 hours after the first dose before taking the second.

You should not take more than 200 milligrams (mg) of Ubrelvy in a 24-hour period.

If you have trouble swallowing tablets, see this article for tips on how to take this form of medication. You can also talk with your doctor or pharmacist.


Some pharmacies offer labels with large print, braille, or a code you scan with a smartphone to convert text to speech. If your local pharmacy doesn’t have these options, your doctor or pharmacist might be able to recommend a pharmacy that does.

It’s important that you do not take more Ubrelvy than your doctor prescribes. For some medications, taking more than the recommended amount may lead to side effects or overdose. To find out about possible side effects with Ubrelvy, see this article.

If you take more than the recommended amount of Ubrelvy

Call your doctor right away if you believe you’ve taken too much Ubrelvy. Another option is to call America’s Poison Centers at 800-222-1222 or use its online tool. If you have severe symptoms, immediately call 911 or your local emergency number, or go to the nearest emergency room.

Below are some frequently asked questions about Ubrelvy’s dosage.

Can I take Ubrelvy with ibuprofen? If so, do I need to adjust my dose of Ubrelvy?

Maybe. You might be able to take Ubrelvy with ibuprofen (Motrin, Advil) if your doctor recommends it. There’s no known interaction between the two drugs.* So doctors typically don’t adjust Ubrelvy dosages with ibuprofen use.

However, be sure to talk with your doctor before taking ibuprofen during Ubrelvy treatment. Your doctor can determine whether taking both drugs is safe for you. And take care to read the dosing information about ibuprofen that comes on the label. You can also ask your pharmacist or doctor what ibuprofen dosage they’d recommend for you.

* For information about drug interactions with Ubrelvy, you can refer to this article.

Is there a recommended dosing chart for Ubrelvy?

No, there’s no dosing chart for Ubrelvy. The recommended dosage is either 50 milligrams (mg) or 100 mg as needed. Your doctor will determine the right dosage for you based on several factors. These include the severity of your migraine episodes, other conditions you have, or medications you take.

If you have questions about the Ubrelvy dosage that’s best for you, talk with your doctor. You can also refer to the “Ubrelvy dosage” section above.

What is the maximum dosage of Ubrelvy per month?

The maximum dosage of Ubrelvy per month is about 1,600 milligrams (mg). This is based on the drug’s maximum daily dosage and the number of treatment days. The maximum dosage of Ubrelvy is 200 mg per day. And it’s not recommended to take Ubrelvy to treat more than eight migraine headaches per month. So, if you take 200 mg for eight migraine episodes, that’s 1,600 mg of Ubrelvy per month.

However, be sure to follow your doctor’s instructions for taking Ubrelvy. They’ll determine the Ubrelvy dosage that’s right for you.

If you typically experience frequent migraine episodes, your doctor may recommend a different treatment.

The dosages in this article are typical dosages provided by the drug manufacturer. If your doctor recommends Ubrelvy for you, they’ll prescribe the dosage that’s right for you. Always follow the dosage that your doctor prescribes.

As with any drug, never change your dosage of Ubrelvy without your doctor’s recommendation. If you have questions about the dosage of Ubrelvy that’s best for you, talk with your doctor.

Besides learning about dosage, you may want other information about Ubrelvy. These additional articles might be helpful:

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.