Vtama (tapinarof) is a brand-name drug that’s prescribed for plaque psoriasis in adults. Vtama comes as a topical cream that’s typically applied to affected areas of skin once per day.

Vtama belongs to a drug class called aryl hydrocarbon receptor agonists. Vtama isn’t available in a generic version.

Keep reading for specific information about the dosage of Vtama, including its strength and how to apply the medication. For a comprehensive look at Vtama, see this article.

Note: This article describes typical dosages for Vtama provided by the drug’s manufacturer. When applying Vtama, always follow the dosage prescribed by your doctor.

Below is information about Vtama’s form, strength, and dosage.

Vtama form

Vtama comes as a topical cream that you apply to your skin.

Vtama strength

Vtama comes in one strength of 1%.

Typical dosages

The following information describes dosages that are commonly prescribed or recommended in adults. However, be sure to apply the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs.

Dosage for plaque psoriasis

Doctors may prescribe Vtama to treat plaque psoriasis.

If your doctor prescribes Vtama cream for plaque psoriasis, you’ll apply a thin layer to the affected areas of skin once per day.

For more information about your specific dosage, talk with your doctor.

How to apply Vtama

To apply Vtama, apply a thin layer of the cream to the areas of skin affected by psoriasis. Do not apply Vtama to your eyes, mouth, vagina, or areas of skin without psoriasis. Wash your hands afterward.

If you have questions about how to apply Vtama, talk with your doctor or pharmacist. There’s also a helpful video and step-by-step instructions on the manufacturer’s website.

Long-term treatment

Vtama is typically prescribed for about 12 weeks to treat plaque psoriasis. Because people applied Vtama to their skin for up to 1 year in clinical trials, your doctor may recommend restarting it if your psoriasis comes back.

Talk with your doctor if you have questions about how long you can expect to apply Vtama.


Some pharmacies offer labels with large print, braille, or a code you scan with a smartphone to convert text to speech. If your local pharmacy doesn’t have these options, your doctor or pharmacist might be able to recommend a pharmacy that does.

It’s important that you do not apply more Vtama than your doctor prescribes. For some medications, applying more than the recommended amount may lead to harmful effects or overdose.

If you apply more than the recommended amount of Vtama

Call your doctor right away if you believe you’ve applied too much Vtama. Another option is to call America’s Poison Centers at 800-222-1222 or use its online tool. If you have severe symptoms, immediately call 911 or your local emergency number, or go to the nearest emergency room.

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.