Xospata (gilteritinib) is a brand-name prescription medication. The Food and Drug Administration (FDA) has approved it to treat acute myeloid leukemia (AML) in certain adults.

Specifically, Xospata can be used in people with a mutation in their cancer called an FLT3 mutation. Your doctor can test your AML to determine if you have an FLT3 mutation and if Xospata may work for you.

Xospata comes as an oral tablet. It belongs to a class of drugs called tyrosine kinase inhibitors.

Xospata is available in a brand-name form only. There’s currently no generic version of Xospata.

Dosage summary

The following chart summarizes Xospata’s dosage. Your doctor will determine the dosage that’s best for you.

Xospata formStrengthTypical dosage
oral tablet40 milligrams (mg)120 mg once daily

For information about the dosage and administration of Xospata, keep reading. For a comprehensive look at Xospata, see this article.

Your doctor will recommend the best dosage of Xospata for you. Below is some information about the typical dosing of Xospata.

Xospata form

Xospata comes as an oral tablet.

Xospata strength

Xospata comes in one strength: 40 milligrams (mg).

Typical dosages

Typically, your doctor will start you taking the recommended dosage of Xospata. In some cases, they may need to adjust your dose over time to reach the amount and frequency that’s right for you. Your doctor will ultimately prescribe the smallest dosage that provides the desired effect.

The following information describes dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs.

Dosage for acute myeloid leukemia

The typical dosage of Xospata for adults with acute myeloid leukemia is 120 mg taken once per day. Since this medication is available only in a tablet strength of 40 mg, the typical dosage is 3 tablets once per day.

In some cases, such as if you have side effects from Xospata, your doctor may recommend a lower dose of medication.

Long-term treatment

Xospata is meant to be a long-term treatment. The drug is typically taken for at least 6 months. If you and your doctor determine that Xospata is safe and effective for you, you’ll likely take it long term.

Here are some frequently asked questions about Xospata.

Is Xospata prescribed for anxiety? If so, what’s its dosage?

No, Xospata is not prescribed for anxiety. This medication is only approved to treat a type of cancer called acute myeloid leukemia.

If you are experiencing anxiety during your treatment with Xospata, talk with your doctor. They can recommend a different medication to help manage your symptoms of anxiety. In some cases, they may recommend that you contact a different doctor, such as a psychiatrist, to discuss your anxiety.

Is Xospata’s dosage based on body weight?

No, your dosage of Xospata is not based on your body weight. Although some medications may have dosages based on your body weight, Xospata is not one of them.

In most cases, your dosage will be 120 milligrams of Xospata once per day, regardless of your body weight. However, in some cases, such as if you have side effects from Xospata, your doctor may recommend a lower dose of medication. Your doctor can help determine the best dosage of Xospata for you.

The Xospata dosage your doctor prescribes will depend on several factors, including side effects that you experience from taking Xospata.

Other medical conditions you take can also affect your Xospata dosage.

Dosage adjustments

Your doctor may recommend a dosage adjustment if you have certain side effects during your treatment with Xospata. Specifically, your doctor may decrease your dose of Xospata if you experience:

  • a heart rhythm change called long QT syndrome
  • pancreatitis (swelling of your pancreas)
  • other side effects that your doctor determines are serious

To learn more about Xospata’s side effects, see this article.

You should take your dose of Xospata once each day. You can take your dose with food or without food.

It may be helpful to take Xospata around the same time of day. This helps maintain a steady level of the drug in your body so Xospata can work effectively.

Be sure to swallow your Xospata tablets whole. Do not break, crush, or chew your tablets.

If you have trouble swallowing tablets, see this article for tips on how to take this form of medication. You can also talk with your doctor or pharmacist.


If you’re having trouble reading your prescription label, talk with your doctor or pharmacist. Some pharmacies offer labels with large print, braille, or a code you scan with a smartphone to convert text to speech. If your local pharmacy doesn’t have these options, your doctor or pharmacist might be able to recommend a pharmacy that does.

If you’re having trouble opening medication bottles, ask your pharmacist about putting Xospata in an easy-open container. They also may recommend tools that can make it easier to open bottles.

If you miss your dose of Xospata and it’s 12 hours or more before your next scheduled dose, take your dose as soon as you remember. Then, return to your typical dosing time the next day. However, if you miss a dose of Xospata and it’s less than 12 hours before your next scheduled dose, skip the missed dose. Do not take more than one dose of Xospata within 12 hours.

If you missed your dose of Xospata and you have questions about when to take your next dose, talk with your doctor or pharmacist. They can help determine the next time you should take your dose of Xospata.

To help make sure that you don’t miss a dose, try using a medication reminder. This can include setting an alarm or using a timer. You could also download a reminder app on your phone.

It’s important that you do not take more Xospata than your doctor prescribes. For some medications, taking more than the recommended amount may lead to side effects or overdose.

If you take more than the recommended amount of Xospata

Call your doctor right away if you believe you’ve taken too much Xospata. Another option is to call the American Association of Poison Control Centers at 800-222-1222 or use its online tool. If you have severe symptoms, immediately call 911 or your local emergency number, or go to the nearest emergency room.

The dosages in this article are typical dosages provided by the drug manufacturer. If your doctor recommends Xospata for you, they will prescribe the dosage that’s right for you. Always follow the dosage that your doctor prescribes for you.

As with any drug, never change your dosage of Xospata without your doctor’s recommendation. If you have questions about the dosage of Xospata that’s best for you, talk with your doctor.

Besides learning about dosage, you may want other information about Xospata. These additional articles might be helpful to you:

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.